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Hims, Roman, and Lemonaid all stand out for the PE pills they provide to help with early climax. See what additional perks each service offers.

Premature ejaculation (PE), sometimes called early climax, occurs when you ejaculate more quickly than you would prefer while enjoying solo play or sex with a partner.

There’s no exact amount of time before ejaculation that counts as premature. Some health experts define PE as ejaculation that happens within 1 minute of penetration (vaginal or anal). But it’s really a matter of preference and what works for you and those you have sex with.

Ejaculating too quickly can make masturbation or sex less pleasurable, affecting your satisfaction and relationships. Several reliable, credible companies sell PE pills that may be able to help you last longer.

Here’s a breakdown of each of the top PE pills so that you can decide how they compare and which one might work best for your sex life.

PricePE treatmentsShippingInsurance
Himsstarting at:
• $24 per month
• $3 per pill (as needed)		• lidocaine spray
• paroxetine
• sertraline		free shipping, discreet packagingnot covered by insurance
Romanstarting at $24 per month for PE treatments• benzocaine wipes
• sertraline
• sildenafil
• tadalafil		free 2-day shipping, discreet packagingnot covered by insurance
Lemonaid• starting at $1 per pill (monthly supply)
• $25 per online consultation (required)		• sertraline
• sildenafil
• tadalafil		free shipping, pickup at local pharmacy or delivery from mail-order pharmacycovered by insurance

*Prices accurate at time of publication.

We vetted every pill or service we recommend with a team of internal experts and chose the top PE pills based on the following factors:

  • How trustworthy or reliable is the product in treating PE?
  • Are reviews generally positive for the product, with negative reviews mainly focused on customer service?
  • Is it easy to regularly use the product to get the best results?
  • Is it affordable to get regular doses of the product without straining your medical expenses?
  • Does research support the use of these products for treating PE or ED?

A serotonin dysfunction in your central nervous system usually causes PE. Serotonin is a neurotransmitter — a chemical messenger that sends signals between nerve cells involved in many processes in your body, including your mood and sleep cycle.

Serotonin works alongside another neurotransmitter, dopamine, which performs many of the same functions. Serotonin and dopamine are both involved in dopamine pathways throughout your body that control physical and reward responses, including ejaculation.

Sertraline can help address disruptions in these dopamine pathways and reduce how quickly you ejaculate.

In a 2021 study, researchers found that sertraline helped with PE whether participants took it daily or as needed. Sertraline was more effective but also had more side effects when taken daily than when taken as needed.

PE can have both physical and psychological causes. Possible physical causes include:

Some causes, such as performance anxiety and feelings of guilt during sex, may be temporary, and you may be able to address them with counseling.

However, some psychological causes may require treatment or long-term counseling, such as:

  • depression
  • stress
  • low self-esteem or a negative body image
  • experience as a perpetrator or survivor of sexual abuse
  • concerns about your romantic relationships

PE can become more noticeable as you get older. PE may also happen with ED, as physiological changes in your body make it harder for you to get and keep an erection. This may make you feel like you have to rush through sex before you lose your erection.

When choosing the right PE pills for your needs, you might consider the following factors:

  • Can you afford the medication?
  • Do you trust the medical care you receive from professionals associated with the company?
  • Are you satisfied with the service you’re receiving from the brand you chose?
  • Can you take the PE pills regularly, considering the potential side effects?
  • Are you willing to take PE pills regularly to get the best results, if needed?
  • Have you consulted a doctor about using PE pills?

Here are some possible side effects of PE pills such as sertraline:

Some of these side effects may become less noticeable or intense after you’ve used PE pills for a few weeks.

It’s advisable to seek medical advice if you’ve tried PE pills and they aren’t working as expected. Underlying medical conditions could also affect your ejaculation timing.

While the services listed in this article offer some access to licensed medical professionals, it’s always best to meet in person with an experienced healthcare professional who you trust and who understands the full picture of your health.

Pills aren’t always the best or only treatment option for PE, and you may need other treatments or visits with specialists, such as cardiologists or urologists, who can check for other health conditions that might affect your sexual performance.

The pills used to help treat PE are used off-label, meaning the use is not approved by the FDA. However, there is some evidence that the pills work.

PE pills work best when used along with lifestyle habits that support healthy sexual function, such as addressing any possible causes of PE that could be related to your mental health and limiting alcohol consumption and recreational drug use.

PE pills such as sertraline may start working immediately — an hour or less after you take them.

But with some pills, you may not notice the effects until you’ve taken them regularly for a few days. How long a PE pill takes to work can also depend on your:

  • diet
  • lifestyle
  • underlying health conditions

Insurance doesn’t cover the cost of prescriptions from Hims or Roman.

Lemonaid does accept some health insurance plans, but it will need to speak with your plan provider to make sure the medications it prescribes are covered. If your insurance does cover the medications, Lemonaid can send them to your local pharmacy of choice.

The Lemonaid websites notes that many customers with insurance decide to pay out of packet due to convenience.

Avoid taking SSRIs such as sertraline and paroxetine if you are taking:

  • monoamine oxidase inhibitors (due to the risk of serotonin syndrome)
  • the antipsychotic medication pimozide
  • the antibiotic linezolid

Also, don’t drink grapefruit juice while taking sertraline because this can cause excessive sertraline to build up in your blood.

To manage PE, you can try exercising your pelvic floor muscles; wearing condoms, which can reduce sensation; and trying different sex positions that may not stimulate your penis nerves as much.

There’s no exact measurement for how quickly is too quickly to ejaculate. But if you’re concerned that you’re finishing too quickly, PE pills may help you last a little longer during masturbation or sex with a partner.

If you can, consult a primary care doctor or any other specialists you may already be seeing before you use online services for PE pills. A healthcare professional can help you avoid possible side effects or interactions with other medications.