There’s no specific recommended Mounjaro diet plan. A healthy diet with Mounjaro generally consists of fresh fruits and vegetables, whole grains, and lean proteins. Avoiding foods high in saturated fat, added sugars, and sodium is also vital.

Mounjaro (tirzepatide) is a GLP-1/GIP receptor agonist. It’s approved by the Food and Drug Administration (FDA) for use with diet and exercise to help manage blood sugar levels in people with type 2 diabetes.

Weight loss is an off-label use of Mounjaro. (Off-label use is when a drug is prescribed to treat a condition other than those it’s approved for.) Another tirzepatide product, called Zepbound, has been recently approved by the FDA for weight loss. (Tirzepatide is the active ingredient in Mounjaro.)

If you’ve been prescribed Mounjaro for weight loss, you may be curious about what you should eat to maximize the drug’s effects. Keep reading to learn more.

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It’s recommended that Mounjaro be used in combination with a healthy diet and exercise. But there’s no single set of guidelines for what you should eat while taking Mounjaro.

Every person taking Mounjaro is different. It’s important to work with your doctor to create an individualized diet plan that addresses your specific dietary needs.

Generally speaking, sticking to a healthy, balanced diet can help you maximize the effects of Mounjaro. This means focusing on foods in the following groups, according to the Dietary Guidelines for Americans.

Vegetables

Vegetables may be fresh, frozen, or canned and include the following:

If you’re taking Mounjaro for diabetes, consider focusing on non-starchy vegetables, as they have a lower carbohydrate content than other vegetable types.

Fruits

Fruits may be fresh, frozen, canned, or dried. This group also includes 100% fruit juice. At least half of your daily fruit intake should be whole fruit. Examples of common fruits include berries, apples, bananas, citrus, and peaches.

The American Diabetes Association notes that the best fruit choices for people with diabetes are those that are fresh, frozen, or canned with no added sugars. The organization also notes that most fruits, except for melons, pineapple, and some dried fruits, have a low glycemic index.

Grains

At least half of your daily grain intake should be whole grains, such as brown rice, oats, and barley. This includes products made with whole grains, such as whole wheat bread.

Other types of grains are refined and include items such as white rice, or are included in products such as white bread and pasta. It’s generally recommended that you limit your intake of refined grains.

Protein

Healthy protein sources include products such as:

Dairy

Dairy includes products such as milk, cheese, and yogurt. In a healthy, balanced diet, most dairy items should be low fat or no fat.

If you want to maximize the effects of Mounjaro, including weight loss, there are certain items you’ll want to avoid. These include:

It’s also important to note that the most common side effects of Mounjaro impact the digestive system. These include nausea, vomiting, indigestion (upset stomach), diarrhea, and constipation. If you experience these side effects, it may be worth avoiding:

Do I need to avoid diet soda during Mounjaro treatment?

You don’t absolutely need to avoid diet soda with Mounjaro. But there are some reasons why you may want to consider limiting your intake, including the following:

  • Higher diet soda intake has been associated with increased abdominal obesity.
  • Researchers have found that sucralose, an artificial sweetener in many diet sodas, may increase appetite.
  • Diet soda consumption has been associated with diabetes and metabolic syndrome.
  • It’s possible that artificial sweeteners may worsen insulin resistance in people with type 2 diabetes.

Below are answers to some of the more frequently asked questions about Mounjaro and weight loss.

Are there any tips and tricks to losing weight with Mounjaro?

In addition to a healthy, balanced diet, it’s important to make other healthy lifestyle changes to lose weight during treatment with Mounjaro. Some examples include:

Approximately how long will it take to lose 25 pounds (lb) with Mounjaro?

Weight loss varies by individual, but drug study results can give us a general idea.

For example, a 2022 study of tirzepatide (the active ingredient in Mounjaro) prescribed for obesity included people with an average weight of 231 lb. After 18 months, participants on the lowest dosage lost an average of 15% (about 35 lb) of their starting body weight. Those on the highest dosage lost an average of 20.9% (about 48 lb) of their starting weight.

How many daily calories should I eat with Mounjaro?

It’s important to talk with your doctor about how many daily calories you should eat during treatment with Mounjaro. In studies of Mounjaro, participants ate a diet with a deficit of 500 calories per day. (This means they ate 500 fewer calories than they burned each day.)

How much protein do I need to eat with Mounjaro?

Currently, the recommended dietary allowance of protein is 0.8 grams (g) per kilogram (kg) of body weight. (One kg equals approximately 2.2 lb). So for an adult weighing 150 lb, that’s roughly 54 g of protein per day. Talk with your doctor about their protein recommendations before starting Mounjaro.

It’s best to focus on a healthy, balanced diet while taking Mounjaro. This includes a diet rich in fresh fruits and vegetables, whole grains, lean protein, and low fat dairy products.

To maximize the effects of Mounjaro, avoid foods that are high in saturated or trans fats, added sugars, and sodium. Individuals with diabetes may also want to avoid food items with a higher glycemic index.

It’s important to talk with your doctor about an appropriate diet plan when starting Mounjaro. They can work with you to recommend a plan that meets your individual dietary needs.