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Healthline only shows you brands and products that we stand behind.

Our team thoroughly researches and evaluates the recommendations we make on our site. To establish that the product manufacturers addressed safety and efficacy standards, we:
  • Evaluate ingredients and composition: Do they have the potential to cause harm?
  • Fact-check all health claims: Do they align with the current body of scientific evidence?
  • Assess the brand: Does it operate with integrity and adhere to industry best practices?
We do the research so you can find trusted products for your health and wellness.

B vitamins are nutrients that play essential roles in your body.

Keep reading for the 10 best dietitian-approved B-complex vitamins to purchase.

There are eight B vitamins plus choline, which is a vitamin-like compound that’s often grouped with B vitamins because it has similar effects on the body (1, 2).

The eight B vitamins are:

  • B1 (thiamine)
  • B2 (riboflavin)
  • B3 (niacin)
  • B5 (pantothenic acid)
  • B6 (pyridoxine)
  • B7 (biotin)
  • B9 (folate)
  • B12 (cobalamin)

Though each B vitamin has unique functions, many of them are involved in the same bodily processes, such as metabolism and acting as cofactors for enzymatic reactions (1).

B-complex supplements contain a combination of B vitamins. Some contain all eight, while others provide just a few. Plus, some contain vitamin-B-like nutrients such as choline and inositol, a type of carbohydrate that was once considered a B vitamin (3, 4, 5).

Although many foods contain B vitamins, a variety of factors — including age, diet, genetic variations, and certain health conditions — can increase your need for B vitamins or negatively affect your absorption of them.

Many populations may need a B-complex supplement, including those who (6, 7):

  • follow a vegan diet
  • have certain genetic mutations
  • are age 65 or older
  • have certain medical conditions
  • are pregnant or breastfeeding
  • take certain medications
  • have substance use disorder

We rounded up the best vitamin B-complex supplements using the following criteria:

  • Vitamin formulations: We prioritized supplements that contain highly absorbable forms of B vitamins, including methylcobalamin, which is the active form of B12, and 5-methyltetrahydrofolate (5-MTHF), which is the biologically active form of folate (8, 9).
  • Additional ingredients: We looked for products that contain minimal amounts of additives, such as fillers, artificial sweeteners, and colors.
  • Dietary needs: We included products to suit a variety of dietary needs and preferences, including gluten-free, major allergen-free, and vegan-friendly.
  • Price: We included supplements to suit a range of budgets.
  • Vetting: The supplements on our list have been vetted to ensure that they align with Healthline’s brand integrity standards and approach to well-being. You can read more about our vetting process.

Why you should trust us

Every brand and product on our list has been vetted to ensure that it aligns with Healthline’s brand integrity standards and approach to well-being. Each product in this article:

  • adheres to allowable health claims and labeling requirements, per Food and Drug Administration (FDA) regulations
  • is manufactured in facilities that adhere to current good manufacturing practices (CGMPs) established by the FDA
  • is produced by a medically credible company that follows ethical, legal, and industry best standards
  • is made by a company that provides objective measures of trust, such as having its supplements validated by third-party labs

A note on price

General price ranges with dollar signs ($–$$$) are indicated below. One dollar sign means the product is rather affordable, whereas three dollar signs indicate a higher price range.

Generally, prices range from $0.30–$1.50 per serving, or $18–$45 per container, though this may vary depending on where you shop.

Liquid formulations and gummies tend to have a higher price per serving than other formulations.

Note that serving sizes vary by product.

Pricing guide

  • $ = under $0.50 per serving
  • $$ = $0.50–$1 per serving
  • $$$ = over $1 per serving

Best subscription vitamin B complex

Care/of B-Complex Vitamin

  • Price: $
  • Type: capsule
  • Active ingredients: thiamine, riboflavin, niacin, vitamin B6, folate, vitamin B12, biotin, pantothenic acid, choline, inositol

Care/of is a vitamin subscription service that provides non-GMO, sugar-free, gluten-free vitamins that don’t contain unnecessary fillers.

Each capsule of the brand’s B-complex vitamin includes 10 mg of vitamin B2, 15 mg of vitamin B6, and 120 mcg of vitamin B12. Care/of claims that this product is great for boosting energy and hair health and supporting the nervous system and metabolism.

Care/of B-Complex Vitamin is cultured with whole and organic foods and is vegan. The company also states that all final products are third-party tested.

Pros

  • third-party tested
  • monthly packs automatically shipped to your door
  • gluten-free
  • non-GMO
  • vegan-friendly
  • contains all eight B vitamins
  • also includes choline and inositol

Cons

  • requires a subscription

Best overall

Nordic Naturals Vitamin B Complex

  • Price: $$
  • Type: capsule
  • Active ingredients: thiamine, riboflavin, niacin, vitamin B6, folate, vitamin B12, biotin, pantothenic acid

Nordic Naturals is best known for its fish oil supplements, but it makes an excellent B-complex supplement as well.

Nordic Naturals Vitamin B Complex contains all eight B vitamins in absorbable forms, including methylcobalamin and 5-MTHF.

All Nordic Naturals supplements are non-GMO, gluten-free, dairy-free, and free of artificial colors, flavors, and preservatives.

The company also offers customers a certificate of analysis (COA) to verify that its products have undergone specified testing and adhere to product specifications and standards.

Pros

  • third-party tested
  • COA easily accessible online
  • contains all eight B vitamins
  • gluten- and dairy-free
  • certified vegan

Cons

  • none

Best for athletes

Integrative Therapeutics Active B-Complex

  • Price: $$
  • Type: capsule
  • Active ingredients: thiamine, riboflavin, niacin, vitamin B6, folate, vitamin B12, biotin, pantothenic acid, choline, inositol

Integrative Therapeutics is a trusted brand in the medical field.

The brand manufactures its supplements in a CGMP-audited facility and uses both in-house and third-party testing to ensure supplement quality.

This supplement is particularly good for athletes because it is NSF Certified for Sport — a certification that ensures products are free of more than 280 substances banned by major athletics organizations (10).

This is a well-rounded B-complex vitamin that contains bioavailable forms of B vitamins, including 5-MTHF and methylcobalamin. In addition to the eight B vitamins, it provides choline and inositol.

Pros

  • third-party tested
  • NSF Certified for Sport
  • contains all eight B vitamins
  • also includes choline and inositol
  • dairy- and gluten-free
  • vegan-friendly

Cons

  • some complaints that the capsules have an unpleasant chalky taste

Best affordable

Pure Encapsulations B-Complex Plus

  • Price: $
  • Type: capsule
  • Active ingredients: thiamine, riboflavin, niacin, vitamin B6, folate, vitamin B12, biotin, pantothenic acid

Pure Encapsulations B-Complex Plus is a great high quality option that’s also budget-friendly. What’s more, it’s certified gluten-free by the Gluten-Free Certification Organization, so it’s a good choice if you have a gluten-related disorder.

Pure Encapsulations claims to exceed standards set by United States Pharmacopeia (USP), a nonprofit organization that sets strict product-specific standards for the quality, purity, and identity of supplements (11).

The company is also CGMP-certified and states that its ingredients are tested by various third-party labs, including Silliker, Eurofins, Intertek, and Advanced Laboratories.

Pure Encapsulations B-Complex Plus contains all eight B vitamins and uses 5-MTHF and methylcobalamin.

Pros

  • certified gluten-free
  • third-party tested ingredients
  • affordable
  • contains all eight B vitamins
  • vegan-friendly

Cons

  • can be difficult to find in local stores

Best to take on an empty stomach

MegaFood Balanced B Complex

  • Price: $$
  • Type: capsule
  • Active ingredients: thiamine, riboflavin, niacin, vitamin B6, folate, vitamin B12, biotin, pantothenic acid, organic food blend

MegaFood Balanced B Complex is a high quality supplement that’s designed to be gentle on the stomach, so you can take it with or without food.

The supplement contains highly absorbable forms of all eight B vitamins, plus a blend of organic brown rice, kale, and broccoli.

While it isn’t third-party tested for purity and potency, all MegaFood supplements are tested for more than 125 pesticides and herbicides.

Pros

  • contains all eight B vitamins
  • gluten-free
  • vegan
  • can be taken with or without food

Cons

  • not third-party tested

Best liquid

Pure Encapsulations B-Complex Liquid

  • Price: $$$
  • Type: liquid
  • Active ingredients: thiamine, riboflavin, niacin, vitamin B6, vitamin B12, pantothenic acid

Pure Encapsulations B-Complex Liquid is a good option for people who don’t like to or can’t swallow pills. It contains six B vitamins: vitamin B12, thiamine, riboflavin, niacin, vitamin B6, and pantothenic acid.

However, this supplement does not contain biotin or folate. If you have increased folate needs, such as during pregnancy, or if you have a genetic variation that impacts folate metabolism, you’ll need to supplement separately with folate.

Pure Encapsulations B-Complex Liquid is sweetened with juice concentrates and stevia, which give it a pleasant taste without added sugar.

Pros

  • convenient liquid formulation
  • third-party tested ingredients
  • certified gluten-free
  • vegetarian-friendly
  • no added sugar

Cons

  • doesn’t contain folate or biotin
  • expensive
  • not vegan-friendly

BrainChild Nutritionals B-Complex Liquid

  • Price: $$$
  • Type: liquid
  • Active ingredients: vitamin B1, vitamin B2, niacin, vitamin B6, folate, vitamin B12, biotin, pantothenic acid, choline, inositol, L-glycine

BrainChild Nutritionals takes pride in using high quality, highly absorbable ingredients in its supplement products.

This B-complex liquid contains all eight B vitamins in highly absorbable forms, plus biotin, inositol, and L-glycine.

L-glycine is an amino acid that’s necessary for a variety of important processes in your body, including the production of glutathione, a powerful antioxidant (12).

BrainChild Nutritionals supplements undergo independent laboratory testing to ensure quality, purity, and potency. They’re free of eggs, gluten, dairy, yeast, corn, refined sugars, and soy, as well as artificial sweeteners, colors, and flavors.

Pros

  • third-party tested
  • includes all eight B vitamins
  • also contains choline, inositol, and L-glycine
  • pleasant lemon flavor

Cons

  • expensive
  • can be difficult to find
  • may not be suitable for vegans

Best vegan

Thorne B-Complex #12

  • Price: $
  • Type: capsule
  • Active ingredients: thiamine, riboflavin, niacin, vitamin B6, folate, vitamin B12, biotin, pantothenic acid, choline

Vegans are at risk of developing a deficiency in certain B vitamins, including vitamin B12, as these nutrients are most concentrated in animal-based foods (13, 14).

Thorne B-Complex #12 is a vegan B-complex supplement that contains all eight B vitamins in active, absorbable forms. Plus, it doesn’t contain any animal-derived ingredients.

Thorne adheres to the CGMPs and boasts an “A” rating from the Therapeutic Goods Association, a regulatory agency run by the Australian Department of Health.

What’s more, Thorne supplements undergo four rounds of in-house testing to ensure quality and purity.

Pros

  • third-party verified
  • provides all eight B vitamins
  • also includes choline
  • gluten-free
  • vegan-friendly

Cons

  • can be difficult to find in local stores

Best gummy

Pure Encapsulations PureNutrients Gummies

  • Price: $$$
  • Type: gummy
  • Active ingredients: thiamine, riboflavin, niacin, vitamin B6, folate, vitamin B12, biotin, pantothenic acid, choline, iodine, zinc, chromium, sodium, fruit blend, and vitamins A, C, D, E, and K

Pure Encapsulations PureNutrients Gummies contain only 2 grams of added sugar per 4-gummy serving — significantly less than many other popular gummy vitamins.

Although this product is not technically a B-complex vitamin, it contains all eight B vitamins in absorbable forms. Plus, these gummies provide other important nutrients, including vitamin D3, vitamin K, a small amount of choline, and zinc.

Gummy vitamins can be easily mistaken for candy. For this reason, it’s important to keep them out of reach of children to prevent accidental ingestion.

Pros

  • easy-to-take gummy formulation
  • third-party tested ingredients
  • provides all eight B vitamins
  • also includes several other important nutrients, such as vitamin D
  • certified gluten-free
  • vegetarian-friendly

Cons

  • expensive
  • contains added sugar
  • not vegan-friendly

Best without B12 and folate

Seeking Health B-Minus

  • Price: $
  • Type: capsule
  • Active ingredients: thiamine, riboflavin, niacin, vitamin B6, biotin, pantothenic acid

This is a good choice for people who cannot tolerate active forms of folate or vitamin B12 and need to supplement separately with these nutrients.

Plus, B-complex supplements without folate and vitamin B12 are ideal for those who need to customize their dosages and forms of these vitamins, such as people with certain genetic variations (15).

Seeking Health B-Minus contains thiamine, riboflavin, niacin, vitamin B6, pantothenic acid, and biotin but not folate or vitamin B12.

Seeking Health adheres to the CGMPs and offers COAs for its products by request.

Pros

  • appropriate for those who can’t tolerate active forms of vitamin B12 or folate
  • COA available by request
  • vegan-friendly
  • gluten-free

Cons

  • not a complete B-complex supplement
  • not third-party tested

Here’s a quick look at how our top picks compare:

Price rangeTypeB vitaminsAdditional nutrientsThird-party testedDietary considerations
Care/of B-Complex Vitamin$capsuleall 8• choline
• inositol
yes• vegan
• gluten-free
Nordic Naturals Vitamin B Complex$$capsuleall 8noneyes• vegan
• gluten-free
Integrative Therapeutics Active B-Complex$$capsuleall 8• choline
• inositol
yes• vegan
• gluten-free
Pure Encapsulations B-Complex Plus$capsuleall 8noneyes• vegan
• certified gluten-free
MegaFood Balanced B Complex$$capsuleall 8organic food blendno• vegan
• gluten-free
Pure Encapsulations B-Complex Liquid$$$liquid6 (missing folate and biotin)noneyes• gluten-free
• vegetarian
BrainChild Nutritionals B-Complex Liquid$$$liquidall 8• choline
• inositol
• L-glycine
yesgluten-free
Thorne B-Complex #12$capsuleall 8cholineyesgluten-free
Pure Encapsulations PureNutrients Gummies$$$gummyall 8• choline
• iodine
• zinc
• chromium
• sodium
• vitamin A
• vitamin D
• vitamin C
• vitamin E
• vitamin K
yes• gluten-free
• vegetarian
Seeking Health B-Minus$capsule6 (missing B12 and folate)noneno• vegan
• gluten-free

When searching for a B-complex vitamin, it’s important to consider the following:

  • Brand reputation and quality: Because the FDA doesn’t regulate supplements in the same way as pharmaceuticals, it’s important to buy from trusted brands such as those listed above. This can help ensure you’re taking a high quality supplement that contains readily absorbable forms of nutrients. When possible, choose a product that’s third-party tested.
  • Your needs: Do you need a supplement that contains all eight B vitamins? Or would you prefer a supplement that contains select B vitamins, such as B12 and folate? It’s also important to discuss optimal doses of B vitamins with a healthcare professional.
  • Cost: Some products cost less than others, but it doesn’t mean they’re low quality. Plenty of affordable, well-formulated B-complex vitamins are available.
  • Type of folate: Many B-complex vitamins contain folic acid, the synthetic form of folate found in food. However, studies suggest that folic acid isn’t as readily absorbed as the active form of folate, 5-MTHF. When possible, look for products that contain 5-MTHF (9).

B vitamins are involved in several essential processes in the body, including energy production, DNA synthesis, and optimal brain functioning (1).

Therefore, B-complex supplements are important for anyone who has or is at risk for B vitamin deficiencies.

These vitamins have also been associated with improvements in stress and mental health. Some studies also suggest they may help manage symptoms of anxiety and depression, though more research is needed (15, 16).

B vitamins are water-soluble, and your body excretes whatever it doesn’t need via urine — but B vitamin toxicity can still happen.

This is why many people have bright yellow urine after taking high dose B vitamins. While it may be surprising, it’s a harmless side effect (17).

However, an excessively high intake of certain B vitamins, such as niacin (B3) and pyridoxine (B6), can lead to complications like nerve damage, vomiting, and even liver damage (18, 19).

While these side effects are rare, it’s important to follow the directions on the supplement bottle or the dosing instructions your doctor provides.

This is especially true when taking a multivitamin that contains fat-soluble vitamins, because your body will not excrete these as it will water-soluble vitamins.

Certain people have increased vitamin B needs that they cannot meet through diet alone. Populations that may benefit from a vitamin B-complex supplement include (20, 21, 22):

  • older adults
  • people with anxiety or depression
  • people who are pregnant or breastfeeding
  • people taking certain medications, such as antidiabetic medications and proton pump inhibitors like Prilosec

A healthcare professional can help you determine whether taking a B-complex vitamin is the right choice for you and suggest an optimal dosage.

To learn more about B-complex vitamins and dosing, read this article.

B vitamin deficiencies can result in a number of symptoms.

For example, a deficiency in vitamin B12 can cause vague symptoms such as fatigue, pale skin and conjunctiva (the tissue lining the inside of the eyelids), tingling in the hands, memory problems, and headaches (23).

A deficiency in vitamin B6 can cause cracking of the corners of the mouth, depression, and weakened immune function (24).

A deficiency in folate or B12 can cause elevations in an amino acid called homocysteine, which can increase the risk of heart disease, impaired thinking ability, and skeletal issues (25).

Many potential symptoms related to B vitamin deficiency can also be symptoms of other underlying health issues. Therefore, it’s important not to self-diagnose and to always visit a healthcare professional for appropriate testing.

Useful supplement shopping guides

Check out these two articles to help make supplement shopping a breeze:

Is it better to take B complex or individual B vitamins?

It depends. Some people, such as those who have a B12 deficiency or need extra choline, can benefit from supplementing with single-nutrient products.

In contrast, other people may benefit from taking a B-complex vitamin that covers their needs for all eight B vitamins.

If you’re not sure which B vitamin product you should be taking, reach out to a healthcare professional for advice.

Is it OK to take a B-complex supplement every day?

Yes. B vitamins are water-soluble, meaning that your body does not readily store them in large amounts and excretes what it doesn’t need through your urine (26).

While B-complex vitamins are generally safe to take daily and can be helpful and even necessary for certain populations, most people can meet their vitamin B needs through diet alone and don’t need to supplement with vitamins every day.

B vitamins are necessary for a variety of essential functions in your body, but many people are at risk for deficiency in one or more B vitamins.

Several high quality B-complex supplements are available to suit various dietary restrictions and nutrient needs.

If you’re looking for a high quality B-complex supplement, consider trying one of the products listed above.

If you’re curious whether a B-complex supplement would benefit your health, consult a trusted healthcare professional for advice.