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Bonafide’s nonhormonal products claim to offer relief from common menopause symptoms. Learn more about the supplement company challenging status-quo treatment for women’s health concerns.

While lifestyle approaches like diet and exercise may help with some menopause discomfort, for severe symptoms of hot flashes, mood changes, or vaginal dryness, hormone replacement therapy (HRT) is often recommended.

But this treatment isn’t without detractors. Among other things, there is some concern that HRT could increase your risk of breast cancer and stroke, making it a difficult choice for many women.

Bonafide is a supplement company focused exclusively on supporting menopause with natural ingredients and, notably, without hormones. Bonafide is also unique in the supplement market for its rigorous clinical research and testing.

Even so, Bonafide’s products, like all supplements, are not regulated by the Food and Drug Administration (FDA).

In this article, we review Bonafide’s line of products, including Revaree and Ristella, and explain what’s known — and not known — about nonhormonal treatments for menopause symptoms.

Pros

  • Bonafide does extensive research and in-house testing.
  • comprehensive line of supplements designed for women
  • clear instructions and indications for which supplements to use
  • many positive reviews online

Cons

  • supplements, in general, are not regulated by the FDA for safety or efficacy
  • Some supplement ingredients may have unknown side effects.
  • can be expensive

Menopause support

Hot flashes? Decreased libido? Mood changes? If you’re experiencing these and other menopause symptoms, get the information you need in Healthline’s Roadmap to Menopause.

Bonafide Health LLC was established in March 2017. The company is not accredited by the Better Business Bureau (BBB), although it has an A- rating on the BBB for responding to customer complaints, addressing concerns, and being transparent with its business practices.

However, the BBB states that it reached out to Bonafide in March 2023 asking the company to prove the following claims: “safe and hormone-free,” “scientifically validated,” “recommended by over 8,300 doctors,” and “7 out of 10 experience symptom relief in 2 months or less.”

The BBB says these statements violate its code of conduct for advertising. Bonafide didn’t respond to the Better Business Bureau or change its advertising claims.

Bonafide states that it does quality testing on all of its ingredients prior to use. It also says it works with current good manufacturing practices (CGMP) compliant third-party labs to test every batch of products and that each batch has a certificate of analysis (COA).

The FDA doesn’t have to evaluate or approve supplements before being sold in the United States. So it’s worth researching a supplement company before buying and using its products.

Bonafide says it’s committed to high quality products. The company indicates that it uses an ISO-17025 certified laboratory for its testing. It also states that it uses ingredients that are GRAS (generally recognized as safe) by the FDA.

Bonafide supplements are evaluated by the National Sanitation Foundation, a rigorous third-party testing measure that requires ongoing evaluation and compliance to maintain certification.

It also claims that its products are USP certified. USP (United States Pharmacopeia) is a nonprofit scientific organization that sets public quality standards for medicines, foods, and supplements.

Since the 1960s, HRT has been one of the most effective and widely used methods for treating severe symptoms of menopause. However, it’s not effective for everyone and is not without risks.

There’s some evidence that HRT may increase the risk of cancer, blood clots, and gallbladder disease. Given the potentially serious risks of HRT, many women prefer to try vitamins or supplements to help alleviate menopause symptoms.

A 2018 review of three randomized, controlled trials evaluating omega-3 fatty acid supplementation to help with symptoms of menopause didn’t find very promising results. Some women did experience a decrease in night sweats, but more research is needed.

Following a nutritious, well-balanced diet can help reduce menopause symptoms. To help make sure you’re getting proper nutrients, you may also want to consider taking a multivitamin if you’re over age 50.

There are a number of nonmedical interventions that may help with menopause discomfort, such as yoga, meditation, hypnosis, and CBT, though there’s not much research supporting their use.

People have used a number of other herbs and vitamins throughout history to help address menopause symptoms. These include black cohosh, St. John’s wort, evening primrose oil, vitamin E, dong quai, and red clover leaf extract.

But a large 2017 review didn’t find any conclusive evidence to support these substances as treatments for symptoms of menopause. It concluded that more research is needed to understand their effects.

Specifically for vaginal dryness, there are a number of topical creams or gels on the market that may relieve sexual discomfort.

The main ingredient in Revaree is hyaluronic acid. A 2013 study of hyaluronic acid used to treat vaginal dryness didn’t find any significant side effects.

Some users experience dripping if they get up during the night or move around a lot while the insert is in place.

Hyaluronic acid, the main ingredient in Revaree, is well known for its moisture retention properties. More than 1,500 online reviews indicate positive results when using Revaree to relieve postmenopausal vaginal dryness.

The FDA doesn’t regulate supplements before they hit the market in the United States. However, Bonafide does go to great lengths to ensure its product quality and safety, such as meeting all FDA manufacturing safety requirements, in-house testing, and third-party testing and certifications. These include NSF and USP certifications.

If you’ve been looking for relief from common menopause symptoms, such as hot flashes, vaginal dryness, sleep issues, mood changes, or hair and skin changes, Bonafide supplements may help.

The company has a strong commitment to quality and safety, and has scientific research backing up its ingredient selections. If you have questions about whether a certain supplement is safe for you, talk with your healthcare professional.