If you have migraine with or without aura, your doctor might suggest Ubrelvy as a treatment option for you. It’s a prescription drug used in adults for the relief of migraine headaches and other migraine symptoms.

The active ingredient in Ubrelvy is ubrogepant. (An active ingredient is what makes a drug work.) Ubrelvy belongs to a group of drugs called calcitonin gene-related peptide (CGFP) antagonists.

This article describes the dosages of Ubrelvy, as well as its strengths and how to take it. To learn more about Ubrelvy, see this in-depth article. It’s important to note that Ubrelvy is not prescribed for migraine prevention.

Note: This article covers Ubrelvy’s usual dosages, which are provided by the drugmaker. But when taking Ubrelvy, always take the dosage that your doctor prescribes.

The dosing chart below highlights the usual dosages of Ubrelvy. All doses are listed in milligrams (mg).

Be sure to read on for more details.

First dose
(when symptoms begin)
Second dose, as needed
(2 hours after first dose)
Maximum dosage in 24 hours
50 mg or 100 mg50 mg or 100 mg200 mg

What is Ubrelvy’s form?

Ubrelvy comes as tablets that you swallow.

What strengths does Ubrelvy come in?

Ubrelvy is available in two strengths:

  • 50 mg
  • 100 mg

What are the usual dosages of Ubrelvy?

The information below describes dosages that are commonly used or recommended. But be sure to take the dosage your doctor prescribes for you. They’ll determine the best dosage to fit your needs.

The typical starting dose of Ubrelvy is 50 mg or 100 mg. If the first dose doesn’t treat your migraine episode, you can take a second dose after 2 hours. The maximum dose for migraine headaches is 200 mg in 24 hours.

It’s not known whether it’s safe to take Ubrelvy for more than eight migraine episodes in 30 days. Be sure to keep track of all your migraine episodes in a month and how much Ubrelvy you take.

If you’re concerned about the frequency of your migraine episodes, talk with your doctor. They may suggest other treatment options if you’re experiencing more than eight migraine headaches per month.

Is Ubrelvy used long term?

Yes, Ubrelvy is usually prescribed as a long-term treatment. If you and your doctor determine that it’s safe and effectively relieves your migraine symptoms, you’ll likely take it as needed for the long term.

Dosage adjustments

Your doctor may need to adjust your Ubrelvy dosage if you have serious liver disease or kidney disease. With these conditions, Ubrelvy can stay in your body longer and increase your risk of side effects.

If you have stage 4 kidney disease, your doctor will recommend that you take only 50 mg of Ubrelvy for the first dose and, if needed, another 50 mg for the second dose. If you have end-stage kidney disease, your doctor will recommend a different medication for you.

If you have Child-Pugh class C liver disease, your doctor will also recommend that you take only 50 mg for both the first and second doses.

If you have problems with your liver or kidneys, talk with your doctor before taking Ubrelvy. They may want to order blood tests to check the health of your liver and kidneys before prescribing this drug for you.

Below are answers to some commonly asked questions about Ubrelvy’s dosage.

Does Ubrelvy have dosing instructions?

Yes. You can review the dosing chart in the “What is Ubrelvy’s dosage?” section above for dosing instructions.

Dosing directions are also provided in Ubrelvy’s prescribing information.

If you still have questions about the dosing instructions, talk with your doctor or pharmacist.

What is the maximum Ubrelvy dose per month?

Taking Ubrelvy to treat more than eight migraine headaches per month is not recommended. Studies haven’t been done to test the safety of taking Ubrelvy more than this. If you’re experiencing more than eight migraine episodes per month, you can talk with your doctor to discuss other treatment options.

Is there a maximum Ubrelvy dose per day?

Yes. The maximum daily dose of Ubrelvy is 200 milligrams (mg). Taking more than 200 mg in a 24-hour period increases your risk of side effects.

If you have serious kidney disease or liver disease, your doctor may lower the maximum dose of Ubrelvy you can take in 24 hours.

If the maximum dose of Ubrelvy doesn’t treat your migraine, ask your doctor about other treatment options.

The dosage of Ubrelvy that your doctor prescribes may depend on several factors. These include:

  • the severity of your migraine symptoms
  • other medications you may be taking
  • other conditions you may have (see “Dosage adjustments” in the “What is Ubrelvy’s dosage?” section above)

Ubrelvy comes as tablets that you swallow. You can take the medication with or without food.

It’s important to note that you should not take a second dose of Ubrelvy if you’ve eaten grapefruit or drunk grapefruit juice within 24 hours of your first dose. Taking Ubrelvy with grapefruit can increase your risk of side effects because grapefruit slows the removal of the drug from your body.

If you have trouble swallowing tablets, see this article for tips on how to take this form of medication.

For information on the expiration, storage, and disposal of Ubrelvy, see this article.

Accessible drug containers and labels

If you find it hard to read the prescription label on your medication, tell your doctor or pharmacist. Some pharmacies provide medication labels that:

  • have large print or use braille
  • feature a code you can scan with a smartphone to change the text to audio

Your doctor or pharmacist may be able to recommend pharmacies that offer these accessibility features if your current pharmacy doesn’t.

Do not take more Ubrelvy than your doctor prescribes, as this can lead to serious side effects. If you have liver or kidney problems, your risk of side effects is greater because the drug can stay in your body longer.

If Ubrelvy isn’t working to treat your migraine symptoms, do not take more than the maximum allowable dosage. Instead, talk with your doctor about other options to manage migraine.

What to do in case you take too much Ubrelvy

Call your doctor right away if you think you’ve taken too much Ubrelvy. You can also call 800-222-1222 to reach America’s Poison Centers or use its online resource. But if you have severe symptoms, immediately call 911 (or your local emergency number) or go to the nearest emergency room.

The sections above describe the usual dosages provided by the drugmaker. If your doctor recommends Ubrelvy for you, they’ll prescribe the dosage that’s right for you.

Remember, you should not change your dosage of Ubrelvy without your doctor’s recommendation. Only take Ubrelvy exactly as prescribed. Talk with your doctor if you have questions or concerns about your current dosage.

Here are some examples of questions you may want to ask your doctor:

  • Would I need to take a lower dose of Ubrelvy if I’m taking other migraine medications?
  • If the 50-mg dose of Ubrelvy doesn’t work to treat my migrainesymptoms, do I need to start with a higher dose next time?
  • Will taking 100 mg of Ubrelvy increase my risk of side effects?
  • Can I take 50 mg of Ubrelvy for my first dose and 100 mg of Ubrelvy for my second dose?

To learn more about Ubrelvy, see these articles:

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.