If you have a certain kind of autoimmune disease, your doctor may prescribe Simponi or Simponi Aria for you.

Simponi and Simponi Aria are prescription drugs used to treat the following conditions in adults:

Simponi is also prescribed to treat ulcerative colitis in adults. And Simponi Aria is also prescribed to treat PsA and polyarticular juvenile idiopathic arthritis in some children.

Simponi and Simponi Aria are prescribed to treat the conditions above in certain situations. To learn more, see “Is Simponi used for ulcerative colitis?” and “Are Simponi and Simponi Aria used for other conditions?” below.

Simponi and Simponi Aria basics

Simponi and Simponi Aria belong to a group of drugs called tumor necrosis factor (TNF) blockers.

Simponi and Simponi Aria contain the active drug golimumab, which is a biologic drug. A biologic medication is made from parts of living cells.

Simponi and Simponi Aria aren’t available in biosimilar forms. (Biosimilars are like generic drugs. But unlike generics, which are made for nonbiologics, biosimilars are made for biologic medications.) Instead, golimumab is available only as the brand-name drugs Simponi and Simponi Aria.

Simponi injection vs. Simponi Aria infusion

Simponi comes as a liquid solution inside single-use, prefilled auto-injector pens and syringes. You or a caregiver will inject Simponi under your skin.

Simponi Aria comes as a liquid solution given as an intravenous (IV) infusion. (An IV infusion is an injection into your vein given over a period of time.)

You’ll receive Simponi Aria at a hospital, a clinic, or an infusion center. You won’t give yourself doses of Simponi Aria.

Read on to learn about side effects, uses, and more for Simponi and Simponi Aria.

Costs of prescription drugs can vary depending on many factors. These factors include what your insurance plan covers and which pharmacy you use. With Simponi Aria, your infusion cost will also depend on the price of your appointment to receive your dose.

If you have questions about how to pay for your prescription, talk with your doctor or pharmacist. You can also visit the Simponi and Simponi Aria manufacturer’s websites to see if they have support options.

Check out this article to learn more about saving money on prescriptions.

Simponi has several indications, including ulcerative colitis (UC). (A drug’s indications are the conditions it’s approved to treat.) Simponi is approved to treat UC in adults. It’s important to note that Simponi Aria isn’t prescribed to treat UC.

Keep reading to learn more about Simponi’s use for UC. And to learn about the other conditions Simponi and Simponi Aria are prescribed to treat, see the “Are Simponi and Simponi Aria used for other conditions?” section below.

UC is a form of inflammatory bowel disease. It usually causes swelling and ulcers (sores) in the lining of your large intestine.

Symptoms of UC can include:

  • weight loss
  • diarrhea
  • bloody stool
  • rectal pain
  • belly pain
  • fever

Simponi is prescribed to treat moderate to severe UC in one of the following situations:

  • UC that requires daily treatment with steroids, such as prednisone (Rayos), to ease symptoms.
  • UC where symptoms haven’t been relieved with other treatments in the past, or past treatments caused bothersome side effects. These include:
    • mercaptopurine (Purinethol, Purixan)
    • azathioprine (Azasan, Imuran)
    • aminosalicylates, such as balsalazide (Colazal) or mesalamine (Asacol HD, Lialda)

Simponi works by blocking a certain protein found in your immune system. Too much of this protein can lead to symptoms of UC. For details, see “How do Simponi and Simponi Aria work?” in the “What are some frequently asked questions about Simponi and Simponi Aria?” section below.

Simponi and Simponi Aria have several indications. (A drug’s indications are the conditions it’s approved to treat.) Simponi is also prescribed to treat ulcerative colitis (UC) in adults, which is described in the “Is Simponi used for ulcerative colitis?” section directly above.

Keep reading to learn how Simponi and Simponi Aria are prescribed to treat conditions other than UC.

Simponi and Simponi Aria are prescribed to treat:

  • Psoriatic arthritis (PsA). For treating PsA, Simponi can be used in adults, and Simponi Aria can be used in adults and in children ages 2 years and older. Simponi can be used alone or with methotrexate (Trexall, Otrexup) or other disease-modifying antirheumatic drugs (DMARDs). Your doctor can determine if Simponi Aria should be used with other treatments for your condition.
  • Rheumatoid arthritis (RA). For RA, Simponi and Simponi Aria can be used in adults. Simponi and Simponi Aria can be used with methotrexate for moderate to severe RA. You may also take other DMARDs for this condition.
  • Ankylosing spondylitis (AS). For treating AS, Simponi and Simponi Aria can be used in adults. Simponi can be used alone or with methotrexate or other DMARDs. Your doctor can determine if Simponi Aria should be used with other treatments for your condition.

Simponi Aria is also approved to treat polyarticular juvenile idiopathic arthritis in children ages 2 years and older.

Simponi and Simponi Aria work by blocking a certain protein found in your immune system. Too much of this protein can lead to symptoms of the conditions listed above. For details, see “How do Simponi and Simponi Aria work?” in the “What are some frequently asked questions about Simponi and Simponi Aria?” section below.

As with most drugs, Simponi and Simponi Aria may cause mild or serious side effects. The lists below describe some of the more common side effects that Simponi and Simponi Aria may cause. These lists don’t include all possible side effects.

Keep in mind that side effects of a drug can depend on:

  • your age
  • other health conditions you have
  • other medications you take

Your doctor or pharmacist can tell you more about the potential side effects of Simponi and Simponi Aria. They can also suggest ways to help reduce side effects.

Mild side effects

Here’s a short list of some of the mild side effects that Simponi and Simponi Aria can cause. To learn about other mild side effects, talk with your doctor or pharmacist, or read Simponi and Simponi Aria’s prescribing information.

Mild side effects of Simponi that have been reported include:

Mild side effects of Simponi Aria that have been reported include:

  • mild infection, such as the common cold or flu
  • infusion reaction, which may happen during or shortly after your Simponi Aria infusion, such as:

Mild side effects of many drugs may go away within a few days to a couple of weeks. But if they become bothersome, talk with your doctor or pharmacist.

Serious side effects

Serious side effects from Simponi and Simponi Aria can occur, but they aren’t common. If you have serious side effects from Simponi or Simponi Aria, call your doctor right away. But if you think you’re having a medical emergency, call 911 or your local emergency number.

Serious side effects of Simponi and Simponi Aria that have been reported include:

* For more information about this side effect, see the “Side effect focus” section below.

Side effect focus

Learn more about some of the side effects Simponi and Simponi Aria may cause.

Boxed warnings

Simponi and Simponi Aria have boxed warnings. A boxed warning is a serious warning from the Food and Drug Administration (FDA). The drugs’ boxed warnings are described below.

Cancer. Simponi and Simponi area may increase your risk of certain cancers. These include leukemia, lymphoma, and skin cancer. But this side effect was rare in studies of Simponi and Simponi Aria.

In some cases, cancer caused by Simponi or Simponi Aria may be fatal. Talk with your doctor to learn more about your risk.

While taking Simponi or Simponi Aria, watch for symptoms of cancer. Keep in mind that symptoms can vary depending on the specific kind of cancer. Cancer symptoms may include:

  • fever
  • weight loss
  • bruising or bleeding more easily than usual
  • fatigue (low energy)

Serious infections. Simponi and Simponi Area may increase your risk of serious infections. But this side effect was rare in studies of Simponi and Simponi Aria.

Some infections with Simponi and Simponi Aria may be severe enough that you need to stay in the hospital to get care. In rare cases, infections from these drugs can be fatal. Talk with your doctor to learn more about your risk.

Serious infections that can occur with Simponi and Simponi Aria may be caused by bacteria, fungi, or viruses. Examples include pneumonia and cellulitis (a painful skin infection).

Symptoms may depend on the specific infection you have, but can include:

  • fever
  • chills
  • fatigue

Simponi and Simponi area may also cause reactivation of tuberculosis (TB) or hepatitis B virus (HBV) in people who’ve had these conditions in the past.

Your risk of serious infections with Simponi and Simponi may be higher if you:

  • are age 65 years or older
  • recently traveled to areas that have a high rate of TB or other infections
  • have infections that are long lasting or keep coming back
  • have certain health conditions that increase your risk of infection, such as diabetes or HIV
  • take certain medications, including:
    • anakinra (Kineret)

What might help

If you’re concerned about your risk of cancer or serious infections with Simponi or Simponi Aria, talk with your doctor.

If you have symptoms of cancer or infection, tell your doctor right away. They can determine whether it’s safe for you to continue treatment.

Your doctor may test you for TB and HBV before and during your treatment with Simponi or Simponi Aria. If you have either condition, your doctor may want to treat it before starting either of these drugs. And they’ll continue to monitor you for TB and HBV during your treatment.

High blood pressure

Some people may have high blood pressure with Simponi or Simponi Aria. But this wasn’t among the most common side effects reported in studies of Simponi and Simponi Aria.

High blood pressure doesn’t usually cause any symptoms unless it’s severe. Symptoms that can occur with severely high blood pressure include dizziness and flushing (temporary warmth, redness, or deepening of skin color).

What might help

If you have symptoms of severely high blood pressure with Simponi or Simponi area, tell your doctor right away. But if your symptoms seem life threatening, call 911 or your local emergency number immediately.

Your doctor will likely check your blood pressure while you’re receiving treatment with Simponi and Simponi Aria. They may also recommend that you monitor your own blood pressure with a home monitor. Your doctor can show you how to use a home monitor and tell you how often to check your blood pressure.

If you’re concerned about your risk of high blood pressure with Simponi or Simponi Aria, talk with your doctor.

Allergic reaction

Some people may have an allergic reaction to Simponi and Simponi Aria. Allergic reaction wasn’t reported in studies of Simponi and Simponi Aria, but it has been reported since the drugs became available for use.

Symptoms of a mild allergic reaction can include:

  • skin rash
  • itchiness
  • flushing (temporary warmth, redness, or deepening of skin color)

A more severe allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include swelling under your skin, usually in your eyelids, lips, hands, or feet. They can also include swelling of your tongue, mouth, or throat, which can cause trouble breathing.

Call your doctor right away if you have an allergic reaction to Simponi and Simponi Aria. But if you think you’re having a medical emergency, call 911 or your local emergency number.

Your doctor will explain how Simponi or Simponi Aria is administered. They’ll also explain how much you’ll be given and how often. Be sure to follow your doctor’s instructions.

Using Simponi and Simponi Aria

Below are details about using Simponi and Simponi Aria.

Injecting Simponi

Simponi comes as a liquid solution inside single-use, prefilled auto-injector pens and syringes. You or a caregiver will inject Simponi under your skin.

You can inject under your skin into these areas:

  • the front of your thighs
  • the back of your upper arms
  • your belly (at least two inches away from your belly button)

Make sure to rotate the injection sites you use. And you shouldn’t inject the drug into skin that is tender, bruised, red or discolored, or hard. For more details about how to give Simponi injections, talk with your doctor or pharmacist. You can also view these step-by-step instructions.

Receiving Simponi Aria

Simponi Aria comes as a liquid solution given as an intravenous (IV) infusion. (An IV infusion is an injection into your vein given over a period of time.)

You’ll receive Simponi Aria at a hospital, clinic, or infusion center. You won’t give yourself doses of the drug.

For details about what to expect with Simponi Aria infusions, talk with your doctor. You can also visit the drug manufacturer’s website.

Accessible medication containers and labels

If it’s hard for you to read the label on your prescription, tell your doctor or pharmacist. Certain pharmacies may provide medication labels that:

  • have large print
  • use braille
  • contain a code you can scan with a smartphone to change the text into audio

Your doctor or pharmacist may be able to recommend a pharmacy that offers these options if your current pharmacy doesn’t.

Using Simponi and Simponi Aria with other drugs

Whether you are prescribed Simponi and Simponi Aria with other drugs will depend on the condition you’ve been prescribed the drugs to treat. Your doctor will tell you whether you’ll use Simponi and Simponi Aria with other drugs for your specific condition.

For example, if you have rheumatoid arthritis, your doctor will usually prescribe Simponi and Simponi Aria with methotrexate (Trexall, Otrexup). Your doctor may also prescribe other disease-modifying antirheumatic drugs (DMARDs) for this condition.

If you have psoriatic arthritis or ankylosing spondylitis, you may be prescribed Simponi alone or with methotrexate or other DMARDs.

Questions about Simponi and Simponi Aria

See below for answers to some questions you may have about Simponi or Simponi Aria.

  • Should I eat before receiving Simponi or Simponi Aria doses? You can receive your Simponi or Simponi Aria doses on an empty stomach or after you’ve eaten. And you don’t need to avoid any foods during your treatment, as these drugs aren’t affected by food.
  • Is there a best time of day to have the Simponi injections? No, there is no best time of day to have Simponi injections. The doses can be administered at any time of day. But it’s recommended that you receive this drug around the same time each day. This ensures there’s a consistent amount of the drug in your body.
Questions for your doctor

You may have questions about your treatment plan with Simponi or Simponi Aria. It’s important to discuss all your concerns with your doctor.

Here are a few tips that might help guide your discussion:

  • Before your appointment, write down questions such as:
    • How will Simponi and Simponi Aria affect my body, mood, or lifestyle?
  • Bring someone with you to your appointment if doing so will help you feel more comfortable.
  • If you don’t understand something related to your condition or treatment, ask your doctor to explain it to you.

Remember, your doctor and other healthcare professionals are available to help you. And they want you to get the best care possible. So don’t be afraid to ask questions or offer feedback on your treatment.

Your doctor will recommend the dosage of Simponi or Simponi Aria that’s right for you. Below are commonly used dosages, but the dosage you receive will be determined by your doctor. Always take the dosage your doctor prescribes.

Forms

Simponi comes as a liquid solution inside single-use, prefilled auto-injector pens and syringes. You or a caregiver will inject Simponi under your skin.

Simponi Aria comes as a liquid solution given as an intravenous (IV) infusion. (An IV infusion is an injection into your vein given over a period of time.)

You’ll receive Simponi Aria at a hospital, clinic, or infusion center. You won’t give yourself doses of this drug.

Recommended dosages

Your exact dosage of Simponi or Simponi Aria depends on several factors. These include:

  • your age
  • your weight (or for children, their body surface area, which is an estimate of body size)
  • the condition you’re receiving the drug to treat
  • whether you receive Simponi or Simponi Aria

With Simponi, you’ll likely inject a dose once per month. But for ulcerative colitis, your first two injections will be given 2 weeks apart. After that, you’ll inject Simponi once per month for the rest of your treatment.

With Simponi Aria, your first two infusions will be given 4 weeks apart. After that, you’ll receive an infusion once every 2 months for the rest of your treatment.

For certain conditions, Simponi and Simponi Aria may be prescribed with other medications. For details, see the “Are Simponi and Simponi Aria used for other conditions?” section above.

Questions about Simponi and Simponi Aria’s dosage

Below are answers to a few questions about Simponi and Simponi Aria’s dosages.

  • What if I miss a dose of Simponi or Simponi Aria? What you’ll do about a missed dose depends on which form of the drug you use.
    • If you miss an injection of Simponi, inject your missed dose as soon as you remember. You can inject the dose after that on your normal schedule. If you aren’t sure when to inject your next dose, talk with your doctor or pharmacist.
    • If you miss an appointment for an infusion of Simponi Aria, call your doctor’s office as soon as you can to reschedule.
  • Will I need to use Simponi or Simponi Aria long term? Yes, most likely. If Simponi or Simponi Aria is working well for you without causing bothersome side effects, your doctor may prescribe the drug long term.
  • How long do Simponi and Simponi Aria take to work? Both Simponi and Simponi Aria start working in your body as soon as you receive a dose. But it may take several weeks for you to notice your symptoms ease. Your doctor can tell you more about what to expect with Simponi or Simponi Aria.

Before taking Simponi and Simponi Aria, talk with your doctor about your health history and other medical conditions you have. Also, tell them about all medications you take.

These considerations are described in more detail below.

Interactions

Taking a medication with certain vaccines, foods, and other things can affect how the medication works. These effects are called interactions.

Before starting Simponi or Simponi Aria, be sure to tell your doctor about all medications you take, including prescription and over-the-counter kinds. Also, describe any vitamins, herbs, or supplements you use. Your doctor or pharmacist can tell you about any interactions these items may cause with Simponi or Simponi Aria.

Interactions with drugs or supplements

Simponi and Simponi Aria can interact with several kinds of drugs.

Doctors usually will not prescribe Simponi or Simponi Aria with the rheumatoid arthritis drugs anakinra (Kineret) and abatacept (Orencia).

Other drugs that may interact with Simponi and Simponi Aria include:

This list does not contain all kinds of drugs that may interact with Simponi and Simponi Aria. Your doctor or pharmacist can tell you more about these interactions and any others that may occur with Simponi or Simponi Aria.

Other interactions

Below are details about other interactions that can happen with Simponi and Simponi Aria.

Live vaccines

You should avoid getting live vaccines during treatment with Simponi or Simponi Aria. Live vaccines contain a weakened form of the viruses or bacteria. But it should be safe to get inactivated (non-live) vaccines during your treatment.

In people with a healthy immune system, live vaccines won’t usually cause an infection. But because of the way Simponi and Simponi Aria work in the body, the drugs can weaken your immune system. As a result, you may have a higher risk of getting an infection from a live vaccine while you’re receiving these medications.

Examples of live vaccines include:

Before getting any vaccines, talk with your doctor or pharmacist. They can advise if it’s safe to get a specific vaccine during treatment with Simponi or Simponi Aria.

Live vaccines and infants

Infants who were exposed to Simponi or Simponi Aria in the womb* should not get any live vaccines until they’re at least 6 months old. These children may have a higher risk of infections if they’re given vaccines soon after birth.

The rotavirus vaccine and MMR vaccine are examples of live vaccines usually given to infants.

If you have questions about your child’s vaccine needs, talk with their doctor.

* For more information about taking Simponi and Simponi Aria during pregnancy, see “Pregnancy and breastfeeding” below.

Boxed warnings

Simponi and Simponi Aria have boxed warnings for cancer and serious infections. These are serious warnings from the Food and Drug Administration (FDA) about drug effects that may be dangerous.

Boxed warnings include:

  • Cancer. Simponi and Simponi area may increase your risk of certain cancers, such as leukemia, lymphoma, and skin cancer. Symptoms of cancer include fever, weight loss, and fatigue (low energy).
  • Serious infections. Simponi and Simponi Area may increase your risk of serious infections, such as pneumonia and cellulitis (a painful skin infection). Some infections may be severe enough that you’ll need to stay in the hospital for care. In rare cases, infections with these drugs can be fatal. Symptoms of infection include fever, chills, and fatigue.

For more information, see the “What are Simponi’s and Simponi Aria’s side effects?” section above.

Other warnings

Simponi and Simponi Aria may not be right for you if you have certain medical conditions or other factors that affect your health. Talk with your doctor about your health history before you start Simponi or Simponi Aria. Factors to consider include those in the list below.

  • Active infection. If you have any infections, talk with your doctor before starting Simponi or Simponi Aria. They’ll likely treat your infection before you start treatment with the drug.
  • Hepatitis B virus (HBV). Before starting Simponi or Simponi Aria, tell your doctor if you currently have HBV or if you’ve had it in the past. These medications may cause reactivation of HBV. Your doctor may test you for HBV before and during your treatment. If you test positive for HBV, your doctor may want to treat it before you start treatment with Simponi or Simponi Aria.
  • Tuberculosis (TB). Before starting treatment with Simponi or Simponi Aria, tell your doctor if you currently have TB or if you’ve had it in the past. These medications may cause reactivation of TB. Your doctor may test you for TB before and during your treatment. If you do have TB, your doctor may want to treat it before you start Simponi or Simponi Aria.
  • Psoriasis. Simponi and Simponi Aria may worsen symptoms of psoriasis. If you have psoriasis, your doctor may monitor your condition more closely than usual. If your psoriasis gets worse during treatment with Simponi or Simponi Aria, your doctor may recommend a different treatment.
  • Heart failure. Simponi and Simponi Aria may cause new or worsening heart failure. If you have heart failure, your doctor can determine whether it’s safe for you to take Simponi or Simponi Aria.
  • Allergic reaction. If you’ve had an allergic reaction to Simponi, Simponi Aria, or any of their ingredients, your doctor will likely not prescribe either of these drugs for you. Ask your doctor what other medications are better options for you.
  • Conditions that cause a weak immune system. Before starting Simponi or Simponi Aria, tell your doctor if you have a condition that weakens your immune system. Examples include diabetes or HIV. These conditions could raise your risk of serious infections with Simponi or Simponi Aria. Your doctor will tell you if it’s safe to receive these drugs with your condition.
  • Allergy to latex or rubber. If you have an allergy to latex or rubber, you may have an allergic reaction to Simponi. This is because the cover of the needle on Simponi syringes and auto-injectors contains a form of rubber similar to latex. Before you start Simponi, tell your doctor if you have an allergy to latex or rubber. They’ll determine if a drug other than Simponi is a better treatment option for you. Simponi Aria vials do not contain latex or rubber.

Simponi, Simponi Aria, and alcohol

There aren’t any known safety issues with drinking alcohol during your treatment with Simponi or Simponi Aria.

But keep in mind that drinking large amounts of alcohol can cause liver problems. And Simponi and Simponi Aria can cause a high level of liver enzymes (proteins), which may be a sign of liver damage. Because of this combined risk of liver problems, it may be best to limit the amount of alcohol you drink while receiving Simponi or Simponi Aria.

If you drink alcohol, talk with your doctor about the amount that may be safe for you to drink during your treatment.

Pregnancy and breastfeeding

It isn’t known if Simponi and Simponi Aria are safe to receive during pregnancy or while breastfeeding.

If you’re pregnant or breastfeeding, or planning to become pregnant or to breastfeed, talk with your doctor before starting treatment with these drugs.

Find answers to some commonly asked questions about Simponi and Simponi Aria.

Can I switch between Simponi and Simponi Aria?

Yes, you may be able to switch between Simponi and Simponi Aria during your treatment. Both drugs are approved to treat psoriatic arthritis, rheumatoid arthritis, and ankylosing spondylitis. If you have any of these conditions, you may be able to switch from one drug to the other.

If you’re interested in switching between these medications, talk with your doctor. If they approve a change from one drug to the other, they’ll tell you how to adjust your treatment plan.

How do Simponi and Simponi Aria work?

Simponi and Simponi Aria work by blocking a certain protein found in your immune system. Too much of this protein can cause your immune system to attack healthy cells in your body. This causes swelling, which can lead to other symptoms of your condition. By blocking this protein, Simponi and Simponi Aria can help relieve your symptoms.

To learn more about how these medications work, you can visit the drug manufacturer’s websites for Simponi and Simponi Aria. You can also talk with your doctor or pharmacist.

Are Simponi and Simponi Aria immunosuppressant drugs?

Yes, Simponi and Simponi Aria are immunosuppressant drugs. They belong to a group of drugs called tumor necrosis factor (TNF) blockers. TNF blockers suppress the activity of your immune system.

Simponi and Simponi Aria work by blocking a certain protein found in your immune system. Too much of this protein can lead to symptoms of UC. For details, see “How do Simponi and Simponi Aria work?” above.

Don’t use more Simponi and Simponi Aria than your doctor prescribes. Using more than this can lead to serious side effects.

What to do in case you receive too much Simponi or Simponi Aria

Call your doctor if you think you’ve received too much Simponi or Simponi Aria. You can also call 800-222-1222 to reach the American Association of Poison Control Centers, or use its online resource. But if you have severe symptoms, immediately call 911 or your local emergency number or go to the nearest emergency room.

If you have a certain kind of autoimmune disease, your doctor may prescribe Simponi or Simponi Aria for you.

Talk with your doctor or pharmacist if you have questions about these medications.

You may also want to ask your doctor about other treatment options for your condition. These articles may be helpful to you:

Below are some questions you may want to ask your doctor about Simponi or Simponi Aria:

  • Will this drug cure my condition?
  • Am I taking any medications that may interact with Simponi or Simponi Aria?
  • Should I use other treatments for my condition during treatment with this drug?

You may also find it helpful to check out Healthline’s communities for psoriatic arthritis and ulcerative colitis.

You can also learn more about one of Simponi and Simponi Aria’s uses by signing up for Healthline’s rheumatoid arthritis newsletter.

Q:

Does my age affect my risk of certain side effects with Simponi or Simponi Aria?

Anonymous

A:

Yes, your age could affect your risk of certain side effects. People ages 65 years and older have a higher risk of infection in general. If you’re in this age group, you may have a higher risk of infection during treatment with Simponi or Simponi Aria.

Some people younger than 18 years old who took a medication similar to Simponi developed cancer. Simponi isn’t approved for use in children. It’s only approved for use in people ages 18 years and older.

Simponi and Simponi Aria also have boxed warnings for the risk of serious infection and cancer. To learn more, see “Side effect focus” under “What are Simponi’s and Simponi Aria’s side effects?” above.

If you have questions about your risk of certain side effects with Simponi or Simponi Aria, talk with your doctor.

Brittany A. Duke, PharmD, RPhAnswers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.
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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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