• Restylane and Juvederm are hyaluronic acid-containing dermal fillers used to plump up the skin and reduce the appearance of wrinkles. These are nonsurgical (noninvasive) procedures.
  • Restylane Silk is used for both lip augmentation and lip lines.
  • Juvederm Ultra XC plumps up the lips, while Juvederm Volbella XC is used for vertical lines above the lip as well as mild plumping of the lips.


  • Minor side effects include swelling, redness, and bruising at the injection site.
  • Serious side effects are uncommon. Scars and discoloration are rare. Sometimes Restylane Silk or Juvederm can lead to numbness, which may be associated with the ingredient lidocaine.


  • Restylane and Juvederm are considered out-patient procedures. They’re done within minutes at your provider’s office.
  • Lip treatments take a shorter amount of time compared to dermal fillers for the cheeks or forehead.


  • Restylane injections cost between $300 and $650 per injection.
  • Juvederm lip treatment averages out at about $600 per injection.
  • No downtime is required.
  • Insurance doesn’t cover dermal fillers, so you may need to talk to your provider about payment plans or financing options.


  • Restylane and Juvederm results are seen quickly and last for several months, but with slight variations.
  • Restylane takes a few days longer to work, and lasts around 10 months.
  • Juvederm lasts about one year. The initial results are instant.
  • With either choice, you’ll need follow-up injections in the future in order to maintain your results.

Restylane and Juvederm are hyaluronic acid-containing dermal fillers used for treating signs of skin aging. Hyaluronic acid has a “plumping” effect that’s useful for both wrinkles andvolumizing the lips.

While both fillers have the same basic ingredients, there are differences in terms of use, cost, and potential side effects.

Read on to learn more about how these fillers compare so you can make the most informed decision with your doctor.

Restylane and Juvederm are nonsurgical (noninvasive) procedures. Both are dermal fillers that contain hyaluronic acid to plump up the skin. They also contain lidocaine to alleviate pain during the procedure.

Each brand has different formulas specifically designed for the lips that are approved by the U.S. Food and Drug Administration (FDA).

Restylane Silk for lips

Restylane Silk is the formula used for the lip area. According to their official website, Restylane Silk was the first lip filler approved by the FDA. It promises “silkier, smoother, natural-looking lips.” Restylane Silk can be used for both lip augmentation as well as smoothing out lip lines.

Juvederm Ultra or Volbella XC for lips

Juvederm comes in two forms for the lips:

  • Juvederm Ultra XC is designed for lip augmentation.
  • Juvederm Volbella XC is used for vertical lip lines, as well as slight volume to the lips.

Depending on what results you’re looking for, your provider may recommend one over the other.

Bruising and swelling are common reactions to filler injections and may be apparent for two to three days. How long these symptoms last can depend on where you’re getting the injections.

If you’re treating lip lines, expect these side effects to go away within seven days. If you’re plumping your lips, side effects can last up to 14 days.

Restylane and Juvederm injection procedures take just a few minutes each. You’ll likely need follow-up sessions in the future to maintain the volumizing effects in your lips.

Restylane duration

It’s estimated that Restylane injections last between 15 and 60 minutes per total procedure. Since the lip area is much smaller compared to other injection areas, the duration is likely to fall on the shorter side of this scale. The effects will show up after a few days.

Juvederm duration

In general, Juvederm lip injections take the same amount of time per procedure as Restylane. Unlike Restylane, though, Juvederm lip results are instant.

Both Restylane and Juvederm are said to produce smooth results due to the plumping effects of hyaluronic acid. However, Juvederm tends to last a bit longer overall with slightly quicker results.

Restylane results

After Restylane Silk injections, you’ll likely see results a few days after your procedure. These fillers are said to start wearing off after 10 months.

Juvederm results

Juvederm Ultra XC and Juvederm Volbella start making a difference in your lips almost instantly. The results are said to last for about a year.

While Restylane and Juvederm lip treatments have FDA approval, this doesn’t mean these procedures are right for everyone. Individual risk factors vary between the two treatments.

As a rule of thumb, dermal fillers in general are off-limits for pregnant women due to unknown safety hazards. Your provider can tell you more about your individual risk factors at your consultation.

Restylane candidates

Restylane is only for adults 21 years of age and older. This lip treatment may not be right for you if you have a history of the following:

  • allergies to hyaluronic acid or lidocaine
  • inflammatory skin conditions, such as psoriasis, eczema, or rosacea
  • bleeding disorders

Juvederm candidates

Juvederm is also only meant for adults over the age of 21. Your provider may not recommend lip injections if you have allergies or sensitivities to lidocaine or hyaluronic acid.

Lip treatments with Restylane or Juvederm are considered aesthetic procedures, so these injections aren’t covered by insurance. Still, these options are less expensive than surgery. They also don’t require any downtime.

You’ll need to ask your provider for a specific estimate for your treatment. The American Society of Plastic Surgeons estimates a general average cost for dermal fillers with hyaluronic acid at $682 per treatment. However, your exact cost depends on how many injections you need as well as your provider and area you live.

Restylane costs

Restylane Silk costs between $300 and $650 per injection. This all depends on the area of treatment. One estimate from the West Coast prices Restylane Silk at $650 per 1 milliliter injection. Another provider based in New York prices Restylane Silk at $550 per syringe.

Interested in Restylane injections for other areas? Here’s how much Restylane Lyft costs for the cheeks.

Juvederm costs

Juvederm lip treatments cost slightly more than Restylane on average. A provider on the East Coast prices Juvederm for smile lines (Volbella XC) at $549 per syringe. Another provider based in California prices Juvederm between $600 and $900 per injection.

Keep in mind Juvederm’s results typically last longer than Restylane. This means you may need lip treatments less often, which affects your total cost.

While both Restylane and Juvederm are noninvasive, this doesn’t mean they’re completely risk-free. Side effects, especially minor ones, are possible.

It’s also important to use the right formula for your lips to avoid potential irritation and scarring. Remember that Juvederm Ultra XC and Volbella XC are the types of formulas used for lips. Restylane Silk is the version of Restylane products used for the lips, too.

Restylane side effects

Some of the possible minor side effects from Restylane Silk include:

  • redness
  • swelling
  • tenderness
  • bruising

Serious side effects include:

  • hyperpigmentation (skin color changes)
  • infection
  • death to the surrounding skin tissues (necrosis)

Serious side effects from Restylane are rare, though.

You may be at an increased risk of side effects if you:

  • smoke
  • have a bleeding disorder
  • have an inflammatory skin condition

Tell your doctor if you’re taking any medications that make you prone to infections.

Juvederm side effects

Like Restylane, Juvederm carries the risk of side effects such as swelling and redness. Some people also experience pain and numbness. Volbella XC formulas sometimes cause dry skin.

Serious but rare side effects from Juvederm injections include:

  • hyperpigmentation
  • scars
  • necrosis

Infections and severe allergic reactions are also rare, but possible.

Tell your doctor if you’re taking any medications that make you prone to infections.

Preventing side effects

For either product, avoid strenuous activities, alcohol, and exposure to the sun or tanning beds for at least 24 hours following lip injections to help prevent side effects.

The manufacturer of Restylane recommends people avoid extreme cold weather after the treatment until any redness or swelling has gone away.

On the other hand, the maker of Juvederm recommends avoiding extreme heat.

Minor side effects from lip treatments go away in one to two weeks, but it can depend on where you’re getting the injections. If you’re treating lip lines, expect these side effects to go away within seven days. If you’re plumping your lips, side effects can last up to 14 days.

Procedure typenonsurgical (noninvasive)nonsurgical (noninvasive)
Costapproximately $300 to $650 per injectionaverage $600 per injection
PainWith the help of lidocaine in Restylane Silk, the injections aren’t meant to be painful.Juvederm products also have lidocaine in them to reduce pain and discomfort.
How long the results lastabout 10 monthsabout 1 year
Expected resultsRestylane treatment results may be seen after a few days following the procedure. These last for several months, but less than a year. Juvederm results are seen immediately after the injections. They last slightly longer (about a year).
Who should avoid this treatment Avoid if any of the following applies to you: allergies to key ingredients, pregnancy or breastfeeding, medications that make you prone to infections, history of skin diseases, or bleeding disorders. Talk to your doctor if you have any of these conditions. Restylane is designed for people over the age of 21.Avoid if any of the following applies to you: allergies to key ingredients, pregnancy or breastfeeding, or medications that make you prone to infections. Talk to your doctor if you have any of these conditions. Juvederm is designed for people over the age of 21.
Recovery timeNone, but if bruising or additional swelling occur, it may take some days for it to go down.None, but if bruising or additional swelling occur, it may take some days for it to go down.

Some dermatologists, plastic surgeons, and aestheticians may be trained and certified in dermal lip fillers like Restylane and Juvederm.

If you already have a dermatologist, this can be your first professional to contact. They may refer you to another provider at this time. As a rule of thumb, your selected provider must be both board-certified and experienced in these lip procedures.

Once you’ve found a few prospective providers, here are some tips on how to proceed:

  1. Set up an initial consultation.
  2. At your appointment, ask the provider about their experience with Restylane and/or Juvederm for lips.
  3. Ask to see a portfolio of their work. It should contain before and after photos to give you an idea of what their work looks like.
  4. Disclose your health history and ask your provider about any potential risks associated with each procedure.
  5. Ask for a cost estimate as well as how many injections/number of procedures are needed per calendar year.
  6. If applicable, ask about what discounts or financing options are available to help off-set your costs.
  7. Discuss the expected recovery time.