If you’re looking at treatment options for depression, you may want to learn more about Trintellix (vortioxetine).

Trintellix is a prescription drug that’s used to treat major depressive disorder in adults. The drug comes as a tablet that you swallow. The active ingredient in Trintellix is vortioxetine. (An active ingredient is what makes a drug work.)

Keep reading for details on Trintellix and cost, and how to save money on prescriptions.

Note: For more details on Trintellix, see this in-depth article.

The price you pay for Trintellix can vary. Your cost may depend on your treatment plan, your insurance coverage (if you have it), and the pharmacy you use.

To learn what you’ll pay for Trintellix, including what your copay may be with your insurance plan, talk with your doctor, pharmacist, or insurance provider.

Note: If you have insurance, you may need to get prior authorization before your insurance provider will cover Trintellix. This means your insurer and your doctor will discuss Trintellix in regard to your treatment. Then the insurance company will determine whether the drug is covered. If Trintellix requires prior authorization and you don’t receive it before you start treatment, you could pay the full cost of the drug.

Be sure to ask your insurance company whether Trintellix requires prior authorization.

Below are answers to some frequently asked questions about Trintellix and cost.

What’s the cost of Trintellix with insurance vs. without insurance?

The cost of Trintellix can vary depending on whether or not you have insurance coverage for the drug.

If you have insurance, your cost for the drug may depend on your specific plan. Your cost may also vary depending on whether you fill your prescriptions at a local pharmacy or through a mail-order pharmacy. If you have insurance, you may qualify for the tAccess Support Program.

If Trintellix is not covered by your insurance or you don’t have insurance, you may qualify to receive the drug at a discounted price through the Takeda Help at Hand Program.

Does the cost of Trintellix depend on the tablet strength (5 mg, 10 mg, or 20 mg)?

It’s possible. The cost of Trintellix depends on several factors, including:

  • the quantity of tablets your doctor prescribes
  • where you fill your Trintellix prescription
  • if you have insurance coverage for the drug

To learn what the cost of Trintellix will be for the dose you’re prescribed, talk with your doctor or pharmacist.

Is there a coupon card available for Trintellix?

Yes. If you have commercial insurance, you may be eligible for copay assistance through the tAccess Support Program.

If you don’t have commercial insurance, talk with your doctor or pharmacist to see if there are other savings options available. Also, the “Can I get help paying for Trintellix?” section lists resources that may be helpful.

Trintellix only comes as a brand-name drug. It’s not currently available in a generic version. A generic drug is an exact copy of the active drug in a brand-name medication. Generics tend to cost less than brand-name drugs.

Why is there such a cost difference between brand-name drugs and generics?

Years of research and testing are needed to ensure that brand-name drugs are safe and effective. This testing can make the drugs expensive. The manufacturer of a brand-name drug can sell the drug for up to 20 years. After that, other drugmakers can create generic versions. This competition in the market can lead to lower costs for generics. And because generics have the same active ingredients as brand-name drugs, they don’t need to be studied again. This can also lead to lower generic costs.

If you take Trintellix long term, you may be able to lower your costs in the following ways:

  • Look into getting a 90-day supply of your medication. You may be able to get a 90-day supply of Trintellix if approved by your insurance company. This could reduce your number of trips to the pharmacy and help lower the cost of Trintellix. If you’re interested in getting a 90-day supply of this drug, talk with your doctor, pharmacist, or insurance provider.
  • Use a mail-order pharmacy to get your medication. Using a mail-order pharmacy might help lower your cost for Trintellix. Plus, you could get your medication without leaving home. Some Medicare plans may help cover the cost of mail-order drugs. You may also be able to get a 90-day supply of the drug through mail order. If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need help covering the cost of Trintellix or understanding your insurance, check out these resources:

On these sites, you can find insurance information, details on drug assistance programs, and links to savings cards and other services.

If you have concerns about how to pay for your prescription, talk with your doctor or pharmacist.

If you still have questions about the cost of Trintellix, talk with your doctor or pharmacist. They may be able to give you a better idea of what you’ll pay for this drug. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you’d pay for Trintellix.

Examples of questions you may want to ask your doctor or insurance provider include:

  • Are there other lower-cost drugs that could treat my depression?
  • What are my options if I can’t afford my medication?
  • Can I fill Trintellix through a mail-order pharmacy?

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.