Nayzilam (midazolam) is a prescription nasal spray used to treat seizures in certain situations. Nayzilam’s cost may depend on factors such as your dosage, whether you have health insurance, and the pharmacy you use.

The price you pay for Nayzilam can vary. Your cost may depend on your treatment plan, your insurance coverage (if you have it), and the pharmacy you use. It will also depend on how much you have to pay for an office visit with your doctor to receive Nayzilam.

To find out how much you’ll pay for Nayzilam, talk with your doctor, pharmacist, or insurance provider. Or check out the section below to learn how much you can save by using an Optum Perks coupon.

To save money on your Nayzilam prescription, explore these Optum Perks coupons.

Save on your Nayzilam prescription

Save on Nayzilam without insurance.

Enter your information:




2 nayzilam (1 Nasal Spray)

Save money without using insurance

Simply show the Optum Perks coupon at your preferred pharmacy or order online and instantly save up to 80% without using insurance. The coupon doesn’t expire, so be sure to save it for refills.

Find your pharmacy

Retail price refers to the manufacturer’s published list price and is up to date as of 3/2023. Retail and discounted prices are U.S.-only and can vary based on region and pharmacy. We cannot guarantee that the discounted price listed here will exactly match the price at your pharmacy. Please contact your pharmacy for the exact price.

Optum Perks and Healthline are subsidiaries of RVO Health.



Was this helpful?

Nayzilam 5-milligram (mg) nasal spray only comes as a brand-name drug. It’s not currently available in a generic version. A generic contains an exact copy of the active drug in a brand-name medication but tends to cost less.

Midazolam is the active ingredient in Nayzilam. Midazolam is available as a generic drug in other forms. But these other forms may not be appropriate for immediate treatment of seizure clusters (what Nayzilam is used for). Talk with your doctor to learn more about the form of midazolam that would be best for your condition.

Why is there such a cost difference between brand-name drugs and generics?

Years of research and testing are needed to ensure that brand-name drugs are safe and effective. This testing can make the drugs expensive. The manufacturer of a brand-name drug can sell the drug exclusively for up to 20 years. After that, other drugmakers can create generic versions. This competition in the market can lead to lower costs for generics. And because generics have the same active ingredients as brand-name drugs, they don’t need to be studied again. This can also lead to lower generic costs.

Below are answers to some frequently asked questions about Nayzilam and cost.

Can you buy midazolam nasal spray online?

Midazolam is the active ingredient in Nayzilam nasal spray. While midazolam is available as a generic in other drug forms, Nayzilam isn’t.

Be careful about purchasing prescription drugs, including Nayzilam (midazolam) nasal spray, online. Only purchase from online pharmacies recommended by your doctor or pharmacist. Some online pharmacies may advertise lower costs, but may also be offering drugs that are unsafe (such as being past their expiration).

You can also check out the Food and Drug Administration (FDA)’s BeSafeRx campaign to learn more about buying prescriptions online safely.

What’s the cost of Nayzilam with insurance?

The cost of Nayzilam with insurance depends on various factors. These include:

Your price may also depend on your dosage and other factors, such as your copay. (A copay is a set amount you pay for each prescription based on the tier the drug is in.)

To learn about the cost of Nayzilam with insurance, talk with your insurance provider or doctor. They can let you know what you can expect to pay for this drug.

Even if you have insurance, check out Optum Perks (a sister site of Healthline) for price estimates for Nayzilam when using coupons from the site. It’s important to note that Optum Perks coupons cannot be used with any insurance copays or benefits.

If you need help covering the cost of Nayzilam or understanding your insurance, check out these resources:

On these pages, you can find insurance information, details on drug assistance programs, and links to savings cards and other services.

If you have questions about how to pay for your prescription, talk with your doctor or pharmacist.

If you take Nayzilam long term, you may be able to lower your costs in the following ways:

Look into getting a 90-day supply of your medication: You may be able to get a 90-day supply of Nayzilam if approved by your insurance company. This could reduce your number of trips to the pharmacy and help lower the cost of Nayzilam. If you’re interested in a 90-day supply of this drug, talk with your doctor, pharmacist, or insurance provider.

Use a mail-order pharmacy to get your medication: Using a mail-order pharmacy might help lower your cost for Nayzilam. Plus, you could get your medication without leaving home. Some Medicare plans may help cover the cost of mail-order drugs. You may also be able to get a 90-day supply of the drug through mail order. If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you have insurance, you may need to get prior authorization before your insurance provider will cover Nayzilam. This means your insurer and your doctor will discuss Nayzilam in regard to your treatment. Then, the insurance company will determine whether the drug is covered. If Nayzilam requires prior authorization and you don’t receive it before you start treatment, you could pay the full cost of the drug.

Be sure to ask your insurance company whether Nayzilam requires prior authorization.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.