Bromelain is a protein-digesting enzyme mixture derived from the stem, fruit, and juice of the pineapple plant. It has a centuries-long history of being used to treat medical ailments, primarily throughout Central and South America. It is currently categorized as a dietary supplement, and generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA).
Bromelain may be used alone or in conjunction with other medications. People use bromelain topically, to remove dead skin from burns, and orally, to reduce inflammation and swelling — particularly of the nasal passages. Bromelain is also used as a digestive aid for osteoarthritis and to reduce soreness in aching muscles.
Bromelain can be purchased in pill or tablet form for oral ingestion. It’s also available as a cream for topical use. Even though it’s extracted from pineapple, eating pineapple or drinking its juice doesn’t supply a large enough dose to be effective.
When using bromelain, it’s important to discuss its use with your doctor and follow the dosing directions provided.
Bromelain is measured in gelatin digesting units (GDUs) per gram. Doses range from 80–400 milligrams per serving, two to three times daily. Your doctor may recommend that you take bromelain with meals in order to aid digestion, or on an empty stomach to reduce inflammation.
Bromelain and its potential health benefits have been studied extensively in multiple areas. These include:
The results of an
Chronic sinusitis (chronic rhinosinusitis)
As with all supplements, it’s important to discuss bromelain with your doctor prior to using it. Bromelain may cause mild side effects in some people, particularly when taken in high doses. These include:
- heavier-than-normal menstrual bleeding
Avoid using bromelain if you take a blood thinner, such as Warfarin, Pradaxa, and others. Bromelain may have an antiplatelet effect on the blood, increasing the potential for excessive bleeding. For this reason, it’s also important to avoid bromelain use before and after surgery.
Bromelain should not be used by people who are allergic to pineapple or to other substances that may elicit an allergic reaction in those allergic to pineapple (cross-reactivity). These substances include:
- grass pollen
Bromelain may also increase the effects of certain medications, such as antibiotics, sedatives, and anti-seizure drugs.
Bromelain is a natural substance derived from pineapples. It has been studied extensively and may have significant, positive effects on multiple health conditions, including burns, osteoarthritis, and cancer. Discuss your use of bromelain with your doctor, particularly if you take prescription medications.