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What to Expect from an Iron Infusion

Overview

Iron infusion is a procedure in which iron is delivered to your body intravenously, meaning into a vein through a needle. This method of delivering medication or supplementation is also known as an intravenous (IV) infusion.

Iron infusions are usually prescribed by doctors to treat iron deficiency anemia. Iron deficiency anemia is typically treated with dietary changes and iron supplements that you take in pill form. In some cases, though, doctors may recommend iron infusions instead.

You may require an IV infusion if you:

  • can’t take iron by mouth
  • can’t absorb iron adequately through the gut
  • can’t absorb enough iron due to blood loss
  • need to increase iron levels fast to avoid medical complications or a blood transfusion
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How to prepare

How to prepare for an iron infusion

Your doctor will give you specific instructions for preparing for your first iron infusion treatment. Some basic things you can do to prepare on the day of your infusion include:

  • eat your breakfast and lunch, as there is no need to fast for an iron infusion
  • take your regular medications
  • be prepared to have a small IV drip put in your arm or hand
  • know how to call for help during your infusion in case you have an adverse reaction

You may feel nervous about your iron infusion. You can help reduce any anxieties by talking about the procedure with your doctor first. They can recommend ways to help you stay comfortable and relaxed during the procedure.

Tips for comfort
  • Wear comfortable, loose-fitting clothing.
  • Have drinking water available.
  • Listen to music.
  • Watch a film or TV show on a tablet or smartphone.
  • Read a book or magazine.

What you need to know about intravenous medication administration »

Procedure

What happens during an iron infusion

An iron infusion usually takes place at a hospital or hemodialysis center. A doctor or other healthcare provider, such as a nurse, will use a needle to insert a small tube into a vein. This small tube is known as a catheter. It’s usually put into a vein in your arm or hand. Then, the healthcare provider will remove the needle, leaving the catheter in your vein.

The catheter is attached to a long tube, which is connected to an IV bag of the iron. The iron has been diluted with a saline solution. This solution is either pumped into your vein or uses gravity to slowly drip down the tube and into your vein.

You may feel a slight pinch in your skin where the IV needle is inserted. There may also be some pressure at the insertion site during the procedure.

The doctor performing the procedure will give you a test dose first to ensure you don’t have any adverse reactions from the iron. If you do, they will stop the procedure.

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How long does it take?

How long does an iron infusion take?

An iron infusion can take up to 3 or 4 hours. You should expect to remain seated for this time. In some cases, the infusion may take a little longer, depending on the level of treatment your doctor thinks you need. The slow infusion rate helps prevent complications.

It often takes several iron infusions to bring the body’s iron levels up to the appropriate levels. You will receive iron infusions over the course of one or a few weeks for your treatments. Iron infusions take time and can be more expensive than other types of anemia treatments.

Side effects

Side effects and complications

After the infusion, you can return to your normal activities straight away. Most people are able to drive themselves home. You can even go back to work after your infusion if you feel up to it.

You may have some side effects right after the procedure. Most of them are mild. These include:

Serious side effects

A rare but serious complication from iron infusions is iron toxicity. The symptoms of iron toxicity may come on quickly, which can cause anaphylactic shock. Or they may come on slowly over time. Iron toxicity that develops over time leads to too much iron in the body’s tissues.

The test dose and the slow infusion rate are both done to prevent this complication. The test dose is also important if you have a history of multiple drug allergies. Your doctor will use the test dose to monitor you for any reactions. These reactions can include:

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Infusion vs. injection

Iron infusion vs. iron injection

Iron infusions involve delivering a dose of iron through the vein with an IV drip. Iron injections involve injecting iron into a muscle with a needle. The injection is usually done into the buttocks. Iron infusions may take up to several hours, whereas iron injections deliver a whole dose immediately.

Iron infusions tend to be less painful than iron injections. Injections can also cause intramuscular bleeding and orange discoloration. Because of these possible complications, doctors often favor iron infusions over iron injections as treatment for iron deficiency anemia.

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In pregnant women

Iron infusions during pregnancy

A pregnant woman’s need for iron increases as her fetus develops. As the fetus absorbs iron from her body, the mother’s iron levels may drop, resulting in anemia. For that reason, doctors sometimes order iron infusions for pregnant women.

Infusions are often preferred over oral iron supplements because taking it by mouth can cause gastrointestinal side effects. However, iron infusions are usually reserved for the second or third trimester of pregnancy. It’s not yet known if it is safe to administer iron infusions during the first trimester.

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Benefits

Iron infusion benefits

An iron infusion is a way to increase the body’s iron levels quickly. It’s a more immediate treatment than supplements or dietary changes. This can be very helpful in situations where anemia is severe.

The physical benefits of an iron infusion include increased energy and easier breathing. You should start feeling these benefits a few weeks after your final infusion treatment. How long these benefits last depends on the cause of your iron deficiency anemia and whether or not you’re using any other therapies to increase your iron levels.

For example, regular blood loss, such as through menstruation, may lead to a chronic drop in iron levels. Depending on your situation, the benefits of an iron infusion may last anywhere from several months to a few years.

Your doctor may recommend additional iron-increasing therapies, such as supplementation and dietary changes, which can prolong the benefits.

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