Vyepti (eptinezumab-jjmr) is a prescription drug that’s used to help prevent migraine episodes. Vyepti’s cost may depend on factors such as your dosage and whether you have health insurance.

Vyepti is used in adults to help prevent migraine episodes. It is not used to treat a migraine episode that’s already happening.

Vyepti is given as an intravenous (IV) infusion (an injection into your vein given over time) by a healthcare professional. It contains the active ingredient eptinezumab-jjmr.* (An active ingredient is what makes a drug work.)

For more details on Vyepti, see this in-depth article.

* The reason “-jjmr” appears at the end of the drug’s name is to show that this drug is distinct from similar medications that may be created in the future.

The price you pay for Vyepti can vary. It may depend on your treatment plan and your insurance coverage (if you have insurance). It will also depend on how much you have to pay for an office visit with your doctor to receive Vyepti infusions. This drug is given as an intravenous (IV) infusion (an injection into your vein given over time) by a healthcare professional.

To find out how much you’ll pay for Vyepti, talk with your doctor or insurance provider.

Note: If you have insurance, you may need to get prior authorization before your insurance provider will cover Vyepti. This means your insurer and your doctor will discuss Vyepti in regard to your treatment. Then the insurance company will determine whether the drug is covered. If Vyepti requires prior authorization and you don’t receive it before you start treatment, you could pay the full cost of the drug.

Be sure to ask your insurance company whether Vyepti requires prior authorization.

Below are answers to some frequently asked questions about Vyepti and cost.

Does Vyepti have a copay card available?

Yes. A program called the Vyepti Connect Copay Assistance Program is available from the drug manufacturer. The program works like a copay card to help lower the cost of Vyepti.

If you have private insurance and you’re eligible to enroll in the program, you can save on Vyepti’s cost. The copay assistance program may also help pay for the cost to receive Vyepti infusions at a clinic or doctor’s office.

To learn more, ask your doctor or insurance provider for more details about the program and whether you qualify based on your current insurance.

Is Vyepti covered by Medicare?

Yes, it’s possible. There are several types of Medicare plans available with different types of benefits. For example, if you have Medicare Part B, it may cover some of the cost of an office visit to receive Vyepti infusions from a healthcare professional.

In some cases, you may still need to pay a percentage of the cost of Vyepti. But if you have a Medicare Advantage plan or Medicare supplemental insurance (Medigap), you could pay even less to receive Vyepti.

To find out the cost and coverage details for Vyepti, talk with your Medicare plan provider or your doctor. They can give you more information on what you can expect to pay.

Vyepti is a biologic drug, which means it’s made from parts of living organisms. It doesn’t come in a biosimilar form. Biosimilars are like generic drugs, but unlike generics (which are made for nonbiologic drugs), biosimilars are made for biologics.

Why is there such a cost difference between biologic drugs and biosimilar drugs?

Biologic drugs can be expensive because of the research and testing needed to ensure their safety and effectiveness. The manufacturer of a biologic drug can sell it for up to 12 years. When the biologic drug manufacturer’s patent expires, other drugmakers can create biosimilar versions. This competition in the market may lead to lower costs for biosimilars. And because biosimilars are very similar to biologic drugs, they don’t need to be studied again. This can also lead to lower costs for biosimilars.

If you need help covering the cost of Vyepti or understanding your insurance, check out these resources:

On these sites, you can find insurance information, details on drug assistance programs, and links to savings cards and other services.

If you have questions about how to pay for your prescription, talk with your doctor.

If you still have questions about the cost of Vyepti, talk with your doctor. They may be able to give you a better idea of what you’ll pay for this drug. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you’d pay for Vyepti.

Examples of questions you may want to ask your doctor or insurance provider include:

  • How does the cost of Vyepti compare with the cost of Aimovig?
  • Would the cost of Vyepti infusions be different at a clinic versus a doctor’s office?
  • Does my dosage affect my cost of Vyepti?

To learn more about Vyepti, see these articles:

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.