Famotidine, sold under the brand name Pepcid and its generic form, is often the first-line treatment for stomach ulcers.

A stomach ulcer is a painful sore that develops in the stomach lining or small intestine caused by Helicobacter pylori (H. pylori) bacterial infection or chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen.

Famotidine (Pepcid) belongs to a class of drugs called H2 blockers, which work by reducing the amount of acid produced in the stomach. It helps treat existing ulcers heal and is also used to prevent ulcers from forming in people who are at higher risk for them. However, Pepcid does not kill the bacteria that cause ulcers. It’s usually taken in combination with other drugs.

However, if you’re experiencing stomach ulcer symptoms, consider speaking with a healthcare professional for a proper diagnosis and treatment plan.

Here we discuss how Pepcid works, its effectiveness, potential side effects, and who can benefit from it.

Pepcid is a histamine-2 (H2) receptor blocker that works by reducing the production of stomach acid. This decrease in stomach acid helps to alleviate the symptoms of existing ulcers and prevent new ones from forming.

Treating existing stomach ulcers

When you have a stomach ulcer, the lining of your stomach or small intestine is damaged, leading to pain and discomfort. Pepcid treats existing stomach ulcers by reducing the amount of acid produced in the stomach, which helps to alleviate symptoms and promote healing.

Preventing stomach ulcers

Pepcid can help prevent stomach ulcers by reducing the production of stomach acid, which helps protect the stomach lining from damage. By inhibiting the secretion of acid, Pepcid creates a less acidic environment, making it harder for ulcers to develop.

Pepcid is considered effective in treating and preventing stomach ulcers by reducing the production of stomach acid. This reduction in stomach acid can help alleviate the symptoms of ulcers and promote healing.

Pepcid is commonly used to manage stomach and duodenal ulcers and can also be prescribed for conditions where excessive stomach acid production occurs, such as Zollinger-Ellison syndrome.

However, consider speaking with a healthcare professional to determine the appropriate dosage and duration of treatment with Pepcid, as its effectiveness may vary depending on individual circumstances.

The most commonly reported side effects include:

Rare but serious side effects of Pepcid can include:

  • skin rash
  • difficulty swallowing or breathing
  • confusion
  • fainting
  • jaundice

Most people tolerate Pepcid well, and severe side effects are rare. However, contact a doctor immediately if you experience severe or persistent side effects.

People who can benefit from taking Pepcid for stomach ulcers include those who:

  • have been diagnosed with gastric (stomach) or duodenal ulcers
  • are seeking to prevent the recurrence of stomach ulcers after healing
  • have conditions that lead to excessive stomach acid production, such as Zollinger-Ellison syndrome
  • are experiencing symptoms like abdominal pain, nausea, or bloating

While Pepcid is considered generally safe and well-tolerated, there are certain situations where it may not be suitable. If you have a known allergy or hypersensitivity to famotidine or its components, do not take Pepcid.

Additionally, consider speaking with a healthcare professional before starting treatment with Pepcid if you:

  • are pregnant or nursing
  • have kidney or liver disease
  • are taking specific medications

Prescription Pepcid is available in various forms, including tablets and oral suspension.

  • Tablets: The recommended dose of Pepcid tablets for treating stomach ulcers is 40 milligrams (mg) once daily at bedtime. However, it’s important to follow the instructions provided by a healthcare professional, as the dosage may vary depending on your condition.
  • Liquid suspensions: Pepcid oral suspension is typically prepared at 8 mg/mL. The recommended dosage and duration can vary, so it’s important to follow the instructions provided by a healthcare professional.
  • Chewable tablets: OTC Pepcid chewable tablets can treat or prevent gastrointestinal ulcers, gastroesophageal reflux disease (GERD), heartburn, and sour stomach. They’re usually taken once or twice daily. To prevent symptoms, it should be taken 15–60 minutes before taking foods that may trigger heartburn.

It’s recommended you use Pepcid for stomach ulcers only under the guidance and prescription of a healthcare professional. They may also recommend other stomach ulcer treatments, such as antibiotics for H. pylori infection in combination with Pepcid to promote healing.

Here are some frequently asked questions about using Pepcid for stomach ulcers.

What are the most common side effects of famotidine?

The most common side effects of famotidine include headaches, dizziness, constipation, and diarrhea. These side effects are usually mild and temporary. However, contact a healthcare professional if you have any concerns or experience severe or persistent side effects.

How much Pepcid should I take for a stomach ulcer?

The recommended dosage of Pepcid for a stomach ulcer in adults is typically 20–40 mg, taken once or twice daily. However, consider speaking with a healthcare professional for an exact dose based on your medical history and condition.

When should I take Pepcid for a stomach ulcer?

The timing of Pepcid administration will depend on a healthcare professional’s instructions. Generally, you can take Pepcid once or twice daily in the morning or at bedtime, with or without food. It’s important to follow the recommended schedule to ensure optimal effectiveness.

How long does it take to heal an ulcer with Pepcid?

Stomach ulcers, also known as peptic ulcers, typically take about 4–8 weeks to heal using Pepcid. However, larger ulcers may take longer to heal.

Pepcid is a widely used medication for treating and preventing stomach ulcers. It reduces stomach acid production, alleviates symptoms, promotes healing of existing ulcers, and prevents the formation of new ones.

While it’s generally well-tolerated, consider speaking with a healthcare professional to determine whether it’s the right choice for you.