Upneeq (oxymetazoline hydrochloride) is a prescription eye solution that’s used to treat droopy eyelids. Upneeq’s cost may depend on factors such as whether you have health insurance and the pharmacy you use.

The price you pay for Upneeq can vary. Your cost may depend on your treatment plan, your insurance coverage (if you have it), and the pharmacy you use.

To find out how much you’ll pay for Upneeq, talk with your doctor, pharmacist, or insurance provider. Or look below in the next section to learn how much you can save by using an Optum Perks coupon.

To save money on your Upneeq prescription, explore these Optum Perks coupons. (Note: Optum Perks coupons cannot be used with any insurance copays or benefits.)

Save on your Upneeq prescription

Save on Upneeq without insurance.

Enter your information:




30 upneeq (1 Box)

Save money without using insurance

Simply show the Optum Perks coupon at your preferred pharmacy or order online and instantly save up to 80% without using insurance. The coupon doesn’t expire, so be sure to save it for refills.

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Retail price refers to the manufacturer’s published list price and is up to date as of 3/2023. Retail and discounted prices are U.S.-only and can vary based on region and pharmacy. We cannot guarantee that the discounted price listed here will exactly match the price at your pharmacy. Please contact your pharmacy for the exact price.

Optum Perks and Healthline are subsidiaries of RVO Health.

Pricing source:Perks.optum.com


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Upneeq comes only as a brand-name drug. It’s not currently available in a generic version. A generic contains an exact copy of the active drug in a brand-name medication but tends to cost less.

Why is there such a cost difference between brand-name drugs and generics?

Years of research and testing are needed to ensure that brand-name drugs are safe and effective. This testing can make the drugs expensive. The manufacturer of a brand-name drug can sell the drug exclusively for up to 20 years. After that, other drugmakers can create generic versions. This competition in the market can lead to lower costs for generics. And because generics have the same active ingredients as brand-name drugs, they don’t need to be studied again. This can also lead to lower generic costs.

If you use Upneeq long term, you may be able to lower your costs in the following ways:

  • Look into getting a 90-day supply of your medication: You may be able to get a 90-day supply of Upneeq if approved by your insurance company. This could reduce your number of trips to the pharmacy and help lower the cost of Upneeq. If you’re interested in getting a 90-day supply of this drug, talk with your doctor, pharmacist, or insurance provider.
  • Use a mail-order pharmacy to get your medication: Using a mail-order pharmacy might help lower your cost for Upneeq. Plus, you could get your medication without leaving home. Some Medicare plans may help cover the cost of mail-order drugs. You may also be able to get a 90-day supply of the drug through mail order.

For more information, contact RVL Pharmacy at 844-785-3937 (844-RVL-EYES). You can also check the drugmaker’s website for more details.

If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need help covering the cost of Upneeq or understanding your insurance, check out these resources:

On these pages, you can find insurance information, details on drug assistance programs, and links to savings cards and other services.

If you have questions about how to pay for your prescription, talk with your doctor or pharmacist.

Below are answers to some frequently asked questions about Upneeq and cost.

How does the cost of Upneeq compare with that of similar drugs, such as Lumify?

Upneeq contains the active ingredient oxymetazoline hydrochloride, and Lumify contains the active ingredient brimonidine tartrate. (An active ingredient is what makes a drug work.) The cost of each of these drugs can depend on several factors.

For example, Upneeq is a prescription eye solution that treats droopy eyelids in adults. You’ll need to visit an eye doctor, dermatologist, or other healthcare professional to get a prescription for Upneeq.

Lumify treats minor eye redness. You can buy Lumify over the counter at any pharmacy or other retail location that sells the product.

Other factors that may affect how much you pay include:

  • whether any savings programs are available for the products
  • whether you have insurance or are paying out of pocket for Upneeq
  • how long your treatment lasts

For questions about the cost of Upneeq and similar drugs, talk with your doctor, pharmacist, or insurance provider. They can share more details on treatment costs based on your specific situation.

What is the cost of Upneeq with insurance?

The cost of Upneeq with insurance depends on various factors. These include:

  • your specific plan benefits
  • if you qualify for any cost savings programs

The cost may also depend on other factors, such as your copay (your share of the cost of a medication).

To learn about the cost of Upneeq with insurance, talk with your insurance provider or your doctor. They can let you know what you can expect to pay for Upneeq.

Even if you have insurance, you can visit Optum Perks* to get price estimates for Upneeq when you use coupons from the site. It’s important to note that Optum Perks coupons cannot be used with any insurance copays or benefits.

* Optum Perks is a sister site of Healthline.

If you have insurance, you may need to get prior authorization before your insurance provider will cover Upneeq. This means your insurer and your doctor will discuss Upneeq in regard to your treatment. Then the insurance company will determine whether the drug is covered. If Upneeq requires prior authorization and you don’t receive it before you start treatment, you could pay the full cost of the drug.

Be sure to ask your insurance company whether Upneeq requires prior authorization.

If you still have questions about the cost of Upneeq, talk with your doctor or pharmacist. They may be able to give you a better idea of what you’ll pay for this drug. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you’d pay for Upneeq.

Examples of questions you may want to ask your doctor or insurance provider include:

  • What are my options if I can’t afford Upneeq?
  • How does the cost of Upneeq compare with generic oxymetazoline eye solution?
  • Can I get a 1-year supply of Upneeq to save more on cost?

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.