Linezolid is a generic prescription drug used to treat certain types of infections in adults and children. Linezolid’s cost may depend on factors including your dosage, whether you have health insurance, and the pharmacy you use.

The price you pay for linezolid can vary. Your cost may depend on your treatment plan, your insurance coverage, and the pharmacy you use. If you’re prescribed the intravenous (IV) infusion form of linezolid, your cost will also depend on how much you have to pay for a healthcare professional to administer the drug.

To find out how much you’ll pay for linezolid, talk with your doctor, pharmacist, or insurance provider. Or look below in the next section to learn how much you can save by using an Optum Perks coupon.

To save money on your linezolid prescription, explore these Optum Perks coupons. (Note: Optum Perks coupons cannot be used with any insurance copays or benefits.)

Save on your linezolid prescription

Save on Linezolid without insurance.

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3000ml linezolid (2 Packages)

Save money without using insurance

Simply show the Optum Perks coupon at your preferred pharmacy or order online and instantly save up to 80% without using insurance. The coupon doesn’t expire, so be sure to save it for refills.

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Retail price refers to the manufacturer’s published list price and is up to date as of 3/2023. Retail and discounted prices are U.S.-only and can vary based on region and pharmacy. We cannot guarantee that the discounted price listed here will exactly match the price at your pharmacy. Please contact your pharmacy for the exact price.

Optum Perks and Healthline are subsidiaries of RVO Health.



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Linezolid is a generic drug. A generic contains an exact copy of the active drug in a brand-name medication. (An active drug is the ingredient that makes a drug work.) A generic is considered just as safe and effective as the original drug but tends to cost less.

Linezolid comes in a brand-name version called Zyvox. To find out how the costs of Zyvox and linezolid compare, talk with your doctor, pharmacist, or insurance provider.

If you’ve been prescribed linezolid and you’re interested in Zyvox instead, talk with your doctor. They may recommend that you try one version instead of the other. You’ll also need to check with your insurance provider, as it may only cover one drug or the other.

Why is there such a cost difference between brand-name drugs and generics?

Years of research and testing are needed to ensure that brand-name drugs are safe and effective. This testing can make the drugs expensive. The manufacturer of a brand-name drug can sell the drug exclusively for up to 20 years. After that, other drugmakers can create generic versions. This competition in the market can lead to lower costs for generics. And because generics have the same active ingredients as brand-name drugs, they don’t need to be studied again. This can also lead to lower generic costs.

If you need help covering the cost of linezolid or understanding your insurance, check out these resources:

On these sites, you can find insurance information, details on drug assistance programs, and links to savings cards and other services.

If you have questions about how to pay for your prescription, talk with your doctor or pharmacist.

Below are answers to some frequently asked questions about linezolid and cost.

How much does linezolid cost without insurance?

The cost of linezolid without insurance depends on several factors. But, in general, your cost will be higher without insurance.

Your cost for linezolid may depend on factors such as:

  • your treatment plan and dosage
  • whether you qualify for any savings programs
  • the form of the drug you’re prescribed
  • the pharmacy you choose

To find out the exact cost of linezolid without insurance, ask your doctor or pharmacist. You may want to check with a few pharmacies to compare prices.

You can also visit Optum Perks* to get price estimates for linezolid when you use coupons from the site. It’s important to note that Optum Perks coupons cannot be used with any insurance copays or benefits.

* Optum Perks is a sister site of Healthline.

Does Medicare cover linezolid?

It’s possible. To find out whether your Medicare plan covers the cost of linezolid, call your plan provider. There are many different types of Medicare plans, and your cost and coverage will depend on your particular plan’s benefits.

If you’re prescribed the IV infusion form of linezolid, your final cost may also depend on how much you have to pay for a healthcare professional to administer the drug.

Keep in mind that your plan may have prior authorization requirements before it will cover linezolid. (See the “Prior authorization” section below for more information.)

You can also ask your doctor about the cost of linezolid if you have Medicare.

If you have insurance, you may need to get prior authorization before your insurance provider will cover linezolid. This means your insurer and your doctor will discuss linezolid in regard to your treatment. Then the insurance company will determine whether the drug is covered. If linezolid requires prior authorization and you don’t receive it before you start treatment, you could pay the full cost of the drug.

Be sure to ask your insurance company whether linezolid requires prior authorization.

If you still have questions about the cost of linezolid, talk with your doctor or pharmacist. They may be able to give you a better idea of what you’ll pay for this drug. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual price you’d pay for linezolid.

Examples of questions you may want to ask your doctor or insurance provider include:

  • How does the cost of linezolid compare with that of similar drugs?
  • What are my options if I can’t afford my medication?
  • How much of a cost difference is there between the different forms of linezolid?

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.