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Getting a good amount of sleep is incredibly important for your health.
What’s more, getting insufficient sleep has been linked to a higher risk of conditions such as heart disease, diabetes, and obesity (5).
Despite this, sleep quality and quantity are at an all-time low, with more and more people experiencing poor sleep (
Keep in mind that good sleep often starts with good sleep practices and habits. However, for some, that’s not enough.
If you require a little extra help to get a good night’s sleep, consider trying the following 9 natural sleep-promoting supplements.
This hormone’s cycle of production and release is influenced by time of day — melatonin levels naturally rise in the evening and fall in the morning.
What’s more, several studies report that melatonin improves daytime sleep quality and duration. This is particularly beneficial for individuals whose schedules require them to sleep during the daytime, such as shift workers (9).
Moreover, melatonin may improve overall sleep quality in individuals with sleep disorders. Specifically, melatonin appears to reduce the time people need to fall asleep (known as sleep latency) and increase the total amount of sleep time (
While there are also studies that didn’t observe melatonin had a positive effect on sleep, they were generally few in number. Those that did observe beneficial effects generally provided participants 3–10 milligrams (mg) of melatonin before bedtime.
Melatonin supplements may improve sleep quality. They seem to be especially helpful if you have jet lag or are doing shift work.
Valerian is an herb native to Asia and Europe. Its root is commonly used as a natural treatment for symptoms of anxiety, depression, and menopause.
Valerian root is also one of the most commonly used sleep-promoting herbal supplements in the United States and Europe (
However, study results remain inconsistent.
Nevertheless, all the observed improvements in these trials and studies were subjective. They relied on participants’ perception of sleep quality rather than on objective measurements taken during sleep, such as brain waves or heart rate.
Despite the lack of objective measurements behind valerian, adults may consider testing it out for themselves.
However, safety remains uncertain for use long-term and in special populations such as pregnant or lactating women.
Valerian root is a popular supplement that may improve sleep quality and sleep disorder symptoms, at least in some people. More studies are needed on the safety of long-term use.
Magnesium is a mineral involved in hundreds of processes in the human body, and it’s important for brain function and heart health.
Studies show that magnesium’s relaxing effect may be partly due to its ability to regulate the production of melatonin. Magnesium is known to relax muscles and induces sleep (
One study found that a combination of magnesium, melatonin, and vitamin B was effective in treating insomnia regardless of the cause. (
Studies report that insufficient levels of magnesium in your body may be linked to troubled sleep and insomnia (
On the other hand, increasing your magnesium intake by taking supplements may help you optimize the quality and quantity of your sleep.
One study gave 46 participants 500 mg of magnesium or a placebo daily for 8 weeks. Those in the magnesium group benefited from overall better sleep quality. This group also had higher blood levels of melatonin and renin, both hormones that regulate sleep (
In another small study, participants given a supplement containing 225 mg of magnesium slept better than those given a placebo. However, the supplement also contained 5 mg of melatonin and 11.25 mg of zinc, making it difficult to attribute the effect to magnesium alone (
It’s worth noting that both studies were performed on older adults, who may have had lower blood magnesium levels to start with. It’s uncertain whether these effects would be as strong in individuals with a good dietary magnesium intake.
Magnesium has a relaxing effect on the body and brain, which may help improve sleep quality.
The lavender plant can be found on almost all continents. It produces purple flowers that, when dried, have a variety of household uses.
Moreover, lavender’s soothing fragrance is believed to enhance sleep.
In fact, several studies show that simply smelling lavender oil shortly before sleep may be enough to improve sleep quality. This effect appears particularly strong in those with mild insomnia, especially females and young individuals (
A small study in older people with dementia also reports that lavender aromatherapy is effective at improving sleep disturbance symptoms. Total sleep time increased. Fewer people also woke up very early (at 3 a.m.) and found themselves unable to get back to sleep (
Another study gave 221 people with anxiety disorder 80 mg of a lavender oil supplement or a placebo per day.
By the end of the 10-week study, both groups had experienced improvements in the quality and duration of sleep. However, the lavender group experienced 14–24% greater effects without any reported unpleasant side effects (
Though lavender aromatherapy is considered safe, the oral intake of lavender has been linked to nausea and stomach pain in some cases. Essential oils are intended for aromatherapy and not oral ingestion (
It’s also worth noting that only a limited amount of studies could be found on the effects of lavender supplements on sleep. Thus, more research is needed before strong conclusions can be made.
Lavender aromatherapy may help improve sleep. More studies on lavender supplements are needed to evaluate their efficacy and safety.
Passionflower, also known as Passiflora incarnata or maypop, is a popular herbal remedy for insomnia.
The species of passionflower linked to sleep improvements are native to North America. They’re also currently cultivated in Europe, Asia, Africa, and Australia.
Participants drank each tea about 1 hour before bed for a period of 1 week, taking a 1-week break between the two teas. Each tea bag was allowed to steep for 10 minutes, and researchers took objective measurements of sleep quality.
At the end of the 3-week study, the objective measurements indicated the participants hadn’t experienced improvements in sleep.
However, when they were asked to rate their sleep quality subjectively, they rated it around 5% higher following the passionflower tea week compared with the parsley tea week (
In a recent study of people with insomnia, those who took passionflower extract over a 2-week-period saw significant improvements in certain sleep parameters when compared with a placebo group (
Those parameters were:
- total sleep time
- sleep efficiency, or the percentage of time spent sleeping as opposed to lying awake in bed
- wake time after sleep onset
On the other hand, a 1998 study compared the effects of a 1.2-gram passionflower supplement, conventional sleeping pills, and a placebo. The researchers found no difference between the passionflower supplements and the placebo (
More studies are needed, but it’s worth noting that passionflower intake is generally safe in adults. For now, it seems that passionflower may provide more benefits when consumed as a tea or extract as opposed to a supplement.
Passionflower tea or extract may help slightly improve sleep quality in some individuals. However, the evidence is mixed and some studies have found no effects. Thus, more studies are needed.
Glycine is an amino acid that plays an important role in the nervous system. Studies show it may also help improve sleep.
In one 2006 study, participants experiencing poor sleep consumed 3 grams of glycine or a placebo immediately before bedtime.
Those in the glycine group reported feeling less fatigued the next morning. They also said their liveliness, peppiness, and clear-headedness were higher the next morning (37).
A 2007 study also investigated the effects of glycine in participants experiencing poor sleep. Researchers took measurements of their brain waves, heart rate, and breathing while they slept.
Participants who took 3 grams of glycine before bedtime showed improved objective measures of sleep quality compared with the placebo group. Glycine supplements also helped participants fall asleep faster (38).
Glycine also improves daytime performance in individuals who are temporarily sleep-deprived, according to one small study.
Participants had their sleep restricted for 3 consecutive nights. Each night, before bedtime, they took either 3 grams of glycine or 3 grams of placebo. The glycine group reported greater reductions in fatigue and daytime sleepiness (
You can buy glycine in pill form or as a powder that can be diluted in water. Taking up to 0.8 grams/kg of body weight per day appears to be safe, but more studies are needed. Many sleep study participants only took 3 grams a day (
You can also increase your glycine intake by eating foods rich in the nutrient, including:
- animal products such as bone broth, meat, eggs, poultry, and fish
- fruits like bananas and kiwis
Consuming glycine immediately before bedtime may help you fall asleep faster and improve the overall quality of your sleep.
There are many additional sleep-promoting supplements on the market. However, not all are supported by strong scientific research.
The list below describes a few additional supplements that may be beneficial to sleep but require more scientific investigation.
- Tryptophan: One study reports that doses as low as 1 gram per day of this essential amino acid may help improve sleep quality. This dosage may also help you fall asleep faster (
- Ginkgo biloba: According to older studies, consuming around 240 mg of this natural herb 30–60 minutes before bed may help reduce stress, enhance relaxation, and promote sleep. Animal studies are also promising (
43, 44, 45).
- L-theanine: Consuming a daily supplement containing up to 400 mg of this amino acid may help improve sleep and relaxation. Animal studies suggest it may be more effective when combined with GABA (
Kava is another plant that’s been linked to sleep-promoting effects in some studies. It originates from the South Pacific islands, and its root is traditionally prepared as a tea. It can also be consumed in supplement form.
However, kava use has also been linked to severe liver damage, potentially due to low-quality production or adulteration. Some countries, like Canada and parts of Europe, have even banned its use (
Proceed with extra caution before using kava. Only buy supplements that have been certified by a reputable third-party organization.
Tryptophan, ginkgo biloba, and L-theanine may also help promote sleep. However, they tend to have fewer studies backing them up, so more research is needed before strong conclusions can be made. Use caution before trying kava for sleep.
Other sleep aids that you can find over the counter are diphenhydramine and doxylamine succinate. They’re both antihistamines.
Diphenhydramine is the active ingredient in popular allergy remedies such as Benadryl. Diphenhydramine’s primary use isn’t as a sleep drug, but it does cause drowsiness and has been used to promote sleep.
Diphenhydramine is also found in ZzzQuil, Unisom SleepGels, and Unisom SleepMelts. Doxylamine succinate is the active ingredient in the sleep aid Unisom SleepTabs.
Other side effects may include dizziness, confusion, and dry mouth (
If you’re interested in trying these sleep aids, you should stick to occasional use. They should never be used for more than 2 weeks at a time (54).
However, people with respiratory conditions, high blood pressure, or heart disease should avoid both of these drugs altogether. They may induce a nervous system reaction that leads to tachycardia, or an elevated heart rate (
Older adults, especially those with liver or kidney issues, shouldn’t use diphenhydramine. They’re at an increased risk of its negative side effects (52).
The antihistamines diphenhydramine and doxylamine succinate may help you sleep, although that isn’t their primary purpose. Much stronger evidence is needed. Also, be aware of the possible side effects before taking these drugs.
You should consult your doctor before using any herbs or OTC medications for sleep, especially since there’s the potential for drug interactions with medications such as blood thinners.
Also, let your doctor know if your sleep troubles last for longer than 2 weeks.
Many OTC sleep aids only result in minor side effects. However, it’s important to be cautious, since relatively little is known about the long-term effects of some of them.
Side effects that have been associated with specific sleep aids are listed below. Some of these side effects were only reported anecdotally or in a few studies, or they were only observed in people who received high doses:
- Melatonin: minor side effects, such as headache, nausea, and dizziness (
- Valerian root: diarrhea, headache, nausea, and heart palpitations (
- Magnesium: diarrhea, nausea, and vomiting, when taken in high doses (
- Lavender: nausea and indigestion (
- Passionflower: dizziness and confusion, on rare occasions (
- Glycine: soft stools and abdominal pain, on rare occasions (59)
- Tryptophan: mild nausea, dry mouth, dizziness, and tremor (
- Ginkgo biloba: mild and rare side effects, such as diarrhea, headache, nausea, and rash (
- L-theanine: no confirmed or direct side effects when taken alone; diarrhea and abdominal pain when combined with L-cystine (61)
In general, women who are pregnant or breastfeeding should speak to their doctors before trying these or any other supplements. Most supplements should be avoided since there’s little research to confirm that they’re safe for this population.
Magnesium, glycine, and tryptophan are all important to fetal development and don’t have to be avoided if you’re pregnant or breastfeeding. However, your doctor will still need to advise you of the proper dosage to avoid potential side effects (
Many OTC sleep aids only result in minor side effects when used short term. You should still consult your doctor before using any herbs or OTC medications for sleep. Avoid most of these products entirely if you’re pregnant or breastfeeding.
If you’re interested in trying these out, you can find most of the above in some form online.
Keep in mind that high-quality sleep is just as important for overall health as eating well and exercising regularly.
Nevertheless, many people have trouble falling asleep, wake up frequently, or fail to wake up feeling rested. This makes it challenging to maintain optimal health and well-being.
Before taking any medications, try incorporating good sleep practices into your routine, such as keeping electronics out of the bedroom and limiting caffeine intake before bedtime.
The supplements above are one way to increase the likelihood of achieving restful sleep. That said, they’re probably most effective when used in combination with good sleep practices and habits.