In anatomy, a plexus is defined as a part of the body full of nerve branches and connections. The uterine artery plexus refers to the part of the uterus where the arteries connect and branch off into different directions. The purpose of the uterine artery is to transport healthy, oxygenated blood into the uterus.

The artery connects to the internal iliac artery at the top. It moves down along the uterus, moving across the front of the ureters, which are small tubes that drain urine into the bladder from the kidneys. The artery then wraps around the cardinal ligament, or main ligament of the uterus, and ends at the uterus itself. The parametrium is a band of tissue that divides the bladder from the cervix, and the artery moves through this area.

The uterine artery plexus supplies proper blood flow to the vagina, uterine tube, uterus, uterine ligaments, and the ovaries. Proper blood flow is necessary for a healthy sex life and healthy reproductive system. When the uterus lacks proper blood flow, it may be difficult or even impossible to achieve orgasm.