The internal pudendal artery branches off the internal iliac artery and delivers oxygenated blood to the external genitalia of both men and women. However, due to gender, there are some anatomical differences.

The artery tends to be smaller in women. Also, some of the branches of the artery are specific to gender. In males, branches of this artery include the dorsal and deep artery of the penis, while females have a dorsal and deep artery of the clitoris. Women have posterior labial branches, whereas men have scrotal branches. There are also other vessels from this artery specific to the genitals.

The inferior rectal and perineal arteries that branch off the internal pudendal artery are the same in both sexes.