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If your regular ol’ CBD oil isn’t doing the trick, you might be ready to experiment with higher potency products. Here are 10 of the strongest CBD oils we recommend.
Healthline has sole editorial control over this article. Potential uses for the products listed here are not health claims made by the manufacturers. The information in this article is intended to be general in nature. It’s not intended to be a substitute for medical advice from a healthcare professional. Healthline encourages you to make any treatment decisions with your healthcare professional.
You can find CBD products — whether broad-spectrum, full-spectrum, or CBD isolate — in a number of different potencies. While there’s no one definition of “strong” CBD, we consider high potency to be at least 50 milligrams (mg) of CBD per 1-milliliter (mL) serving.
However, keep in mind that CBD affects everyone differently, so what feels strong to you may not feel as potent to another person. That’s especially true if you’re brand new to CBD.
Each product in this article contains at least 50 mg of CBD per mL of product.
There are lots of high-potency products out there, so we narrowed things down with criteria we think are good indicators of safety, quality, and transparency.
Each product in this article:
is made by a company that provides proof of third-party testing by an ISO 17025-compliant lab
For now, the FDA does not guarantee the safety, effectiveness, or quality of over-the-counter CBD products.
You can avoid purchasing CBD products that are misrepresented or mislabeled by looking for products that come with an up-to-date COA from a reputable third-party lab.
Once you have the COA, review it to make sure the amount of CBD and THC in the product matches what’s advertised.
Contaminant testing results are another important area to review. These vary by brand, but in general, it’s good practice to keep an eye out for testing results for pesticides, heavy metals, and molds.
It’s also always a good idea to make sure you’re buying from a company that’s transparent about where they grow their hemp and how they produce their products.
This information should be readily available on the brand’s website so you can review it before buying.
CBD dosage
To learn how many drops to use, follow the recommended dosage provided by the manufacturer or your healthcare professional.
Proper serving sizes for CBD vary widely depending on individual factors, like:
intended use
body weight
metabolism
body chemistry
The four factors listed above should be considered on a case-by-case basis as CBD can work differently in individuals.
It’s always best to start with a small dose so that, if needed, you can increase it over time until you reach your preferred results.
Doses should be spaced at least 4–6 hours apart but can be taken at any time of day. Of course, if you’re looking to improve sleep, take CBD before bed.
The immediate effects of CBD typically happen within 30–90 minutes. Depending on your preferred method of administration, the immediate effects may vary.
Long-term results may take a number of weeks to accomplish.
CBD oils can be used by placing them under your tongue using a dropper (most CBD oils come with one) or by mixing them into drinks and food.
Shake the bottle before dropping the dose under your tongue. If you’re looking for maximum absorption, keep it under your tongue for 30 seconds to a few minutes before swallowing.
To store, safely secure the cap on your CBD oil and keep it in a dry, cool place. You can also stick it in the refrigerator to extend its shelf life.
Research on the safety of CBD is limited. However, a 2017 study suggests that most people can safely tolerate dosages of up to 1,500 mg CBD per day.
A 2022 study found that oral 1,500 mg CBD treatments did not seem to produce feelings of intoxication in healthy adults. Researchers also note it’s doubtful that CBD can negatively affect cognitive function or driving ability.
Still, CBD affects everyone differently. You may experience some side effects if you take higher doses of CBD. If you take a higher dose of a full-spectrum CBD oil, you may feel psychoactive effects.
Research around CBD is still ongoing, so the best practice is to check in with a qualified healthcare professional before testing it out.
For example, one 2019 animal study flagged the possibility that CBD may lead to liver damage and interact with certain medications. But this study was done in mice, so research in humans is needed to explore this potential side effect.
It may take some trial and error with CBD oils at varying potency levels to decide if a stronger CBD oil is best for your needs.
Side effects may be more likely at higher dosages.
A 2020 systematic review of human trials showed CBD to be relatively safe at various doses. Most of the studies in this review used daily doses of 300–600 mg.
Note that these doses are specific to the patient populations included in the studies and may not be the right dose for you.
Strong CBD isn’t the best choice for everyone, especially for people new to CBD.
If you’re new to CBD, start with the lowest dose you can before slowly increasing it until it feels right for you. This means beginning with low dose CBD products and avoiding full-spectrum CBD products.
Broad-spectrum CBD and CBD isolate seem to be good options for people new to CBD. Seeing how you react with a low dose option before testing the waters with stronger products is a good rule of thumb.
Strong CBD is also not for people taking other supplements or medications. CBD can interact with some medications, especially those with a grapefruit warning. Talking with your healthcare professional before adding CBD to your routine is always a good idea.
Strong CBD may increase the risk of side effects like fatigue, diarrhea, appetite changes, and weight changes. People looking to avoid side effects shouldn’t take high doses of CBD.
Strong CBD is also not for people looking to avoid THC. Many strong CBD products are full-spectrum, which contain trace amounts of THC. Even if your CBD product is listed as THC-free, it’s still possible that it contains enough THC to show up on a drug test or cause psychoactive effects.
Although there’s no one definition of the “strongest” CBD, we consider high potency to be at least 50 mg of CBD per 1-mL serving.
Remember to start with a small dose so that you can increase it and frequency over time until you reach your desired effect.
Talk with a healthcare professional before trying any CBD products.
Is CBD legal? The 2018 Farm Bill removed hemp from the legal definition of marijuana in the Controlled Substances Act. This made some hemp-derived CBD products with less than 0.3% THC legal at the federal level. However, CBD products containing more than 0.3% THC still fall under the legal definition of marijuana, making them illegal at the federal level. Some states have legalized CBD, so be sure to check state laws, especially when traveling. Also, keep in mind that the FDA has not approved nonprescription CBD products, and some products may be inaccurately labeled.
Breanna Mona is a writer based in Cleveland, Ohio. She holds a master’s degree in media and journalism and writes about health, lifestyle, and entertainment.
Last medically reviewed on November 29, 2023
How we reviewed this article:
Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.
Crockett J, et al. (2020). A phase 1, randomized, pharmacokinetic trial of the effect of different meal compositions, whole milk, and alcohol on cannabidiol exposure and safety in healthy subjects. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065230/
