If you’re living with psoriatic arthritis (PsA), you’ve got quite a number of treatment options. Finding the best one for you and your symptoms may take some trial and error. By working with your healthcare team and learning more about the different types of treatments, you too can achieve PsA relief.

Injectable medications for PsA

There are currently six injectable biologic medications for PsA:

  • adalimumab (Humira)
  • certolizumab (Cimzia)
  • etanercept (Enbrel)
  • golimumab (Simponi)
  • infliximab (Remicade)
  • ustekinumab (Stelara)

The main benefits of biologics are that they can stop inflammation at the cellular level. At the same time, biologics are known to weaken the immune system, which can leave you susceptible to other diseases.

Oral medications for PsA

Nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and disease-modifying antirheumatic drugs (DMARDs) are generally taken by mouth, although some NSAIDs can be applied topically.

NSAIDs include:

  • ibuprofen (Advil, Motrin IB)
  • naproxen (Aleve)
  • celecoxib (Celebrex)

The main benefits of NSAIDs are that most are available over the counter. However, they can cause stomach irritation and bleeding. They may also increase your risk of a heart attack or stroke.

DMARDs include:

  • leflunomide (Arava)
  • cyclosporine (Neoral, Sandimmune)
  • methotrexate (Trexall)
  • sulfasalazine (Azulfidine)
  • apremilast (Otezla)

Biologics are a subset or type of DMARD, so they also work to suppress or reduce inflammation.

Corticosteroids include:

  • prednisone (Rayos)

Also simply known as steroids, these prescription drugs work to reduce inflammation. Again, they are also known to weaken the immune system.