Ductal prostate cancer is a rare subtype of prostate cancer that is often diagnosed in later stages than other types.
Ductal adenocarcinoma prostate cancer, or simply ductal prostate cancer, is a rare subtype of prostate cancer that tends to be more aggressive than acinar adenocarcinoma, according to
Ductal prostate cancer tends to be diagnosed at a later stage than acinar adenocarcinoma. Doctors often treat it in the same way as high risk acinar adenocarcinoma, with some combination of:
Read on to learn more about this rare type of prostate cancer and how it differs from acinar adenocarcinoma.
- difficulty starting urination
- trouble emptying your bladder completely
- frequent urination
- weak or interrupted urine flow
- burning during urination
- painful ejaculation
Many people have advanced prostate cancer by the time they receive a diagnosis. Signs of advanced prostate cancer depend on where the cancer spreads, but they can include:
- sore and swollen lymph nodes in your groin
- unexplained weight loss
- leg swelling or weakness
- pain around your pelvis, back, or hips
- feeling out of breath
Learn more about prostate cancer symptoms.
As with most cancers, researchers don’t know exactly why some people develop ductal prostate cancer.
Cancer happens when genetic changes cause your cells to replicate out of control. It’s likely that a combination of your genetics and environmental factors plays a role in these genetic changes.
Researchers have identified certain genetic changes that are common in people with ductal prostate cancer. For example, a fusion of TMPRSS2 and ERG is identified in
Prostate cancer becomes more common with age. In a
Other risk factors for prostate cancer include having a family history of prostate cancer or being of African American and Caribbean men of African ancestry, according to the
Learn more about prostate cancer risk factors.
Ductal prostate cancer is more likely to be diagnosed at a later stage than acinar adenocarcinoma. Cancer that spreads to distant body parts becomes harder to treat.
Prostate cancer can cause many concerns if it spreads beyond the prostate. The specific complications it causes depend on where it spreads. They might include:
Doctors use a variety of tests to diagnose prostate cancer, such as:
- blood tests to measure prostate-specific antigen (PSA) levels
- digital rectal examination, where your doctor examines your prostate with a gloved finger
- magnetic resonance imaging
Ductal prostate cancer
Ductal prostate cancer is usually treated like high risk acinar adenocarcinoma. The
- a type of surgery called radical prostatectomy and radiation therapy for prostate cancer confined to the prostate
- androgen deprivation therapy with chemotherapy for cancer that’s spread to distant body parts
Researchers are continuing to examine the potential benefits of newer treatment options like
Learn more about prostate cancer treatment.
Doctors have improved their understanding of ductal prostate cancer over the years. Researchers now know that it’s an aggressive subtype of prostate cancer, with poorer outlook than acinar adenocarcinoma.
Here are some frequently asked questions people have about ductal prostate cancer:
How fast does ductal prostate cancer grow?
Ductal prostate cancer tends to grow quickly and act aggressively, compared with acinar adenocarcinoma of the prostate. In the
What is the difference between acinar and ductal prostate cancer?
Acinar and ductal adenocarcinoma cells look different when examined under a microscope. For example, ductal cancer cells tend to appear column-like, while acinar adenocarcinoma cells tend to appear more cubic.
What’s the difference between ductal and intraductal prostate cancer?
The terms “ductal prostate cancer” and “intraductal prostate cancer” are often mixed up.
Ductal prostate cancer is a rare type of prostate cancer that tends to be more aggressive than the most common type of prostate cancer, called acinar adenocarcinoma. It’s more often diagnosed in a later stage and tends to spread to distant body parts quicker.
Doctors often treat ductal prostate cancer with surgery and radiation therapy for cancers limited to the prostate. Chemotherapy and hormone therapy are often used to treat cancers that have spread to distant body parts.