Nonalcoholic steatohepatitis (NASH) is an advanced type of nonalcoholic fatty liver disease (NAFLD). NAFLD is characterized by excess fat buildup in your liver that’s not related to alcohol use. In addition to fat, NASH also involves inflammation and damage to the liver.
Most of the current therapies for NASH are based in changing your diet and lifestyle but treating other underlying comorbidities may also help.
Learn more about the available NASH treatment options that you may consider discussing further with a doctor or healthcare professional.
As of 2022, there’s no Food and Drug Administration (FDA)-approved medication or other treatment for NASH or NAFLD. Some possible medications are currently being studied, including those that target glucose (sugar) and lipid (fat) metabolism to help reduce inflammation and fibrosis of the liver.
Until potential medications become available, the treatment for NASH and NAFLD instead consists of management strategies. For NASH, the focus is to reduce further liver injury and possibly reduce any underlying fat and inflammation on the liver.
It’s thought that NASH is
Reaching a moderate weight
Having overweight and obesity are both considered risk factors for developing NASH but losing weight may help you manage it. While a moderate weight is highly individual and can depend on other factors such as your height and genes, gradually losing weight may decrease the effects of NASH.
Speak with a doctor about how you can get started with gradually losing weight. Some strategies may include:
Abstaining from alcohol
While NASH and NAFL are not caused by heavy alcohol consumption, abstaining from alcohol is recommended for anyone with liver disease. As
Lowering sugar intake
Diets that are high in sugary foods and beverages
Lowering total cholesterol
High cholesterol is another condition seen with NASH, though diet and exercise may help. The
Regular exercise is key to managing your weight and lowering the risk of chronic illnesses. While the general recommendation is at least 30 minutes per day, a doctor may encourage more than this amount.
Moderate exercises that increase your heart rate and make you sweat are best and may include fast walking, jogging, and swimming.
However, if you’re new to exercise, speak with a doctor first. They’ll likely recommend starting with lower intensity exercises first before you gradually work your way up to more moderate workouts.
Managing your blood pressure
High blood pressure is another risk factor for metabolic syndrome, which may be associated with NASH. In addition to regular exercise, you may be able to help manage your blood pressure with a healthy diet and a daily sodium intake lower less than
One diagnostic tool that’s used in NASH and not NAFL is a liver biopsy.
When left untreated, the underlying inflammation and damage associated with NASH
This may further cause cirrhosis, or permanent scarring of the liver. Having cirrhosis also
Additionally, having NAFLD
A diagnosis of NASH may raise many questions you may wish to discuss with a doctor. Below are a few common questions and answers to help you get started:
What is NASH?
NASH is a form of NAFLD that also causes inflammation in your liver. This inflammation can lead to permanent liver damage and possibly
Are there medications to treat NASH?
Instead, you may consider speaking with a doctor about ways to manage NASH through diet, exercise, and other lifestyle strategies. Also, be aware of claims surrounding supplements or vitamins as “cures” for NASH, as these may do more harm than good.
Is NASH reversible?
Left untreated, NASH may lead to permanent liver damage. However, the condition itself is reversible. In fact, significant improvements in your metabolic profile could potentially lead to normal liver function again in the future.
What should you eat if you have NASH?
Eating a diet that focuses on vegetables, fruits, and whole grains can help you manage NASH. One recommendation is the Mediterranean diet, which focuses more on plant-based foods that are naturally low in saturated fats rather than animal-based foods.
It’s also recommended that you focus on healthy (plant-based fats), such as olive oil, as these are lower in saturated fat.
NASH is a type of NAFLD that’s often associated with metabolic disorders. It’s characterized by excess fat accumulation, as well as inflammation that can potentially damage healthy liver tissues.
There’s currently no medication available to treat NASH, which makes diet, exercise, and other management strategies important in preventing and reversing damage to your liver. Speak with a doctor for more information about how you may manage specific comorbidities you might have with NASH.