You could be more likely to get the flu or other infections while taking Gilenya since it calms your immune system. This calming effect slows down your body’s response to infection. Read More »
A headache is a fairly common side effect of Gilenya. Call 911 or go to an emergency room if you have a severe headache while taking Gilenya. Read More »
If you experience changes in vision after starting Gilenya, like blurred vision, call your doctor right away. This usually stops after the drug is discontinued. Read More »
A virus causes this serious brain infection. Symptoms include progressive weakness or clumsiness on one side of the body and changes in vision or thinking. Read More »
You could have nausea or diarrhea while taking Gilenya. This should improve within a few days or weeks after you start taking the drug.
Read More »
You may have back pain while taking Gilenya. Read More »
Your heart rate can slow down with this drug. This effect can last for a few days or weeks, but it usually returns to normal. Read More »
Symptoms can include nausea, vomiting, stomach pain, tiredness, yellowing of the eyes or skin, and dark urine. See your doctor right away if these happen to you. Read More »
Influenza or Other Infections
Progressive Multifocal Leukoencephalopathy
Nausea or Diarrhea
Slowed Heart Rate
Changes in Liver Enzymes
Gilenya is an oral
drug used to treat relapsing-remitting multiple sclerosis (RRMS). This drug
helps prevent white blood cells from circulating in the body. As your white
blood cell count goes down, this may calm your immune system. The result is
that the drug may prevent white blood cells from entering the central nervous
system and causing the damaging effects of multiple sclerosis (MS).
clinical studies were described in the FDA label for Gilenya. The
first study lasted two years. Those who took Gilenya had fewer relapses than
those who didn’t take it. Those who took Gilenya also had less than one-third
the number of new or enlarged lesions when they were studied on MRI scans. In
the second study, participants took either Gilenya or interferon
beta-1a. When those who took Gilenya were compared with those who took
interferon beta-1a, the people taking Gilenya had half the relapse rate and
also 40 percent fewer new or enlarged lesions.
The dosage of Gilenya is one capsule per day. It can be taken with food. The
drug level in your body will slowly increase and reach its maximum in one or
A headache is a fairly common side effect of Gilenya. You should call 911
or go to the emergency room if you have a severe headache, vision changes, or a
seizure. This is a medical emergency.
Some people may have vision changes after starting Gilenya, such as
blurred vision. Call your doctor right away if this happens. These changes
usually stop once you have quit using the drug. Don’t stop taking Gilenya
without first speaking with your doctor about it.
A very rare side effect of Gilenya is progressive multifocal
leukoencephalopathy (PML). PML is a serious brain infection caused by a virus.
The symptoms of PML include:
- weakness or
clumsiness on one side of the body
- changes in
vision or thinking
You should see your doctor right away if you think you have PML.
Slowed Heart Rate
Your heart rate can slow down with this drug. You will take the first
dose of Gilenya at your doctor’s office so that your heart rate can be monitored.
A reduced heart rate can last for a few days or weeks, but it usually returns
Drugs that slow the heart rate can be dangerous if taken with Gilenya.
Some of these include:
Alcohol doesn’t actually interact with Gilenya, but it can
dehydrate you and increase your risk of changes in the way your heart beats.
Adding this effect to Gilenya’s effect on the heart could be risky.
Gilenya can increase liver enzymes and cause liver damage. Call
your doctor if you have the symptoms of liver damage, which include:
- a loss of
of the eyes or skin
- dark urine
Gilenya may cause diarrhea or abdominal pain. Speak with your doctor if you
have these symptoms.
Gilenya changes the way your immune systems functions. People taking
Gilenya have an increased risk of influenza, or the flu, and other infections
because of this change in your immune system.
Vaccines interact with Gilenya because the immune response may be poor
and you risk infection. Talk to your doctor and pharmacist about Gilenya and
vaccines before you start taking the drug.
Drugs that affect your immune system can interact with Gilenya. These
Corticosteroids, like prednisone, further
reduce your immune function while you’re taking Gilenya. Tell your doctor if you’re taking corticosteroids.