Highlights for meloxicam
- Meloxicam oral tablet is available as both a generic and brand-name drug. Brand name: Mobic.
- Meloxicam is also available as a capsule and liquid suspension. The capsule is only available as the brand-name drug Vivlodex. The suspension is only available as the brand-name drug Mobic.
- Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID). It’s used to treat pain and inflammation caused by osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
FDA warnings: Potentially fatal heart risk and stomach problems
- This drug has a Black Box Warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients to potentially dangerous effects.
- This drug may increase your risk of developing a blood clot, heart attack, or stroke, which can be fatal. Your risk may be higher if you’re taking it long term, at high doses, or if you already have heart problems or risk factors for heart disease, such as high blood pressure. You shouldn’t take meloxicam for pain before, during, or after heart bypass surgery. This can increase your risk for a heart attack or stroke.
- This medication may increase your risk of developing stomach and intestinal problems. These include bleeding, ulcers, and holes in your stomach or intestines, which can be fatal. These effects can occur any time while you’re taking this drug. They may happen without any signs or symptoms. Adults aged 65 years and older are at higher risk of these stomach or intestinal problems.
- Allergy warning: Don’t take meloxicam if you’ve had itchy skin, symptoms of asthma, or an allergic reaction to aspirin or other NSAIDs. A second reaction could be much more severe.
- May cause liver damage: This drug may affect your liver. Symptoms may include yellowing of your skin or whites of your eyes and liver inflammation, damage, or failure. Your doctor may check your liver function while you take this drug.
- Blood pressure warning: This medication may increase or worsen your blood pressure. This can increase your risk of heart attack or stroke. Your doctor may check your blood pressure while you’re taking meloxicam. Some medicines for high blood pressure may not work as well as they should when you’re taking meloxicam.
What is meloxicam?
Meloxicam oral tablet is a prescription drug that’s available as the brand-name drug Mobic. It’s also available as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name versions.
It also comes in a capsule and a liquid suspension. The suspension is only available as the brand-name drug Mobic. The capsule is only available as the brand name drug Vivlodex.
Why it's used
Meloxicam decreases inflammation and pain. It’s approved to treat:
- rheumatoid arthritis
- juvenile arthritis in people aged 2 years or older
How it works
Meloxicam belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs help reduce pain, inflammation, and fever.
It isn’t known how this medication works to decrease pain. It may help reduce swelling by lowering levels of prostaglandin, a hormone-like substance that usually causes inflammation.
Meloxicam side effects
Meloxicam oral tablet doesn’t cause drowsiness. However, it can cause other side effects.
Most common side effects
The most common side effects that occur with meloxicam include:
- abdominal pain
- indigestion or heartburn
- itching or rash
Serious side effects
If you experience any of these serious side effects, call your doctor right away. If your symptoms are potentially life threatening, or if you think you’re experiencing a medical emergency, call 9-1-1.
- heart attack. Symptoms may include:
- chest pain or discomfort
- trouble breathing
- cold sweat
- pain or discomfort in one or both arms, your back, shoulders, neck, jaw, or area above your belly button
- stroke. Symptoms may include:
- numbness or weakness of your face, arm, or leg on one side of your body
- sudden confusion
- trouble speaking or understanding speech
- vision difficulty in one or both eyes
- difficulty walking or loss of balance or coordination
- severe headache with no other cause
- stomach and intestinal problems, such as bleeding, ulcers, or tearing. Symptoms may include:
- severe stomach pain
- vomiting blood
- bloody stools
- black, sticky stools
- liver damage. Symptoms may include:
- dark urine or pale stools
- not wanting to eat
- pain in your stomach area
- yellowing of your skin or whites of your eyes
- increased blood pressure: Symptoms of extreme high blood pressure may include:
- dull headache
- dizzy spells
- water retention or swelling. Symptoms may include:
- rapid weight gain
- swelling in your hands, ankles, or feet
- skin problems, such as blistering, peeling, or red skin rash
- kidney damage. Symptoms may include:
- changes in how much or how often you urinate
- pain with urination
- decreased red blood cells (anemia)
Abdominal pain, diarrhea, upset stomach, and nausea occur very often. Pain, vomiting, and diarrhea may occur more often in children than adults. Sometimes these side effects can cause more serious stomach problems.
Mild side effects may disappear within a few days or a couple of weeks. Talk to your doctor or pharmacist if they’re more severe or don’t go way.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
Meloxicam may interact with other medications
Meloxicam oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
Examples of drugs that can cause interactions with clopidogrel are listed below.
- sodium polystyrene sulfonate (Kayexalate)
Combining this drug with meloxicam oral suspension can severely damage parts of your intestine, which can be fatal. Do not take meloxicam oral suspension with sodium polystyrene sulfonate.
Nonsteroidal anti-inflammatory drugs (NSAIDs)
Meloxicam should not be taken at the same time as other NSAIDs because of severe stomach problems, ulcers, and bleeding.
Rheumatoid arthritis drug
Combining these drugs may increase the negative effects cyclosporine has on your kidneys. Your risk is increased if you’re dehydrated.
Disease-modifying antirheumatic drug
Meloxicam may cause methotrexate to build up in your body. This may increase side effects of methotrexate, such as decreased red blood cells, abdominal pain, diarrhea, nausea, and liver damage.
Anticoagulant, blood thinners
Combining meloxicam with anticoagulant medications raises your risk of bleeding.
Antidepressants and anxiety drugs
- selective serotonin reuptake inhibitors, such as citalopram
- selective serotonin and norepinephrine reuptake inhibitors, such as venlafaxine
Combining meloxicam with some antidepressant and anxiety medications raises your risk of bleeding.
These include blood pressure medications.
- angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers
- These may not work as well to decrease blood pressure.
- water pills (diuretics), such as hydrochlorothiazide.
- These may not work as well to remove water or lower your blood pressure.
Combining these drugs with meloxicam can also cause kidney damage.
Bipolar disorder drug
Blood levels of lithium may increase when you take higher doses of meloxicam. This can cause upset stomach, confusion, increased reflexes or muscle movements that you can’t control, and other effects.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
Meloxicam oral tablet comes with several warnings.
Meloxicam can cause a severe allergic reaction. Symptoms may include:
- trouble breathing
- swelling of your throat or tongue
Don’t take meloxicam if you have asthma, runny nose, and nasal polyps (aspirin triad). Don’t take it if you’ve had itching, difficulty breathing, or an allergic reaction to aspirin or other NSAIDs.
Warnings for people with certain health conditions
For people with heart or blood vessel diseases: This medication increases your risk of blood clots, which can cause a heart attack or stroke. It may also cause fluid retention, which is common with heart failure.
For people with high blood pressure: This medication may make your blood pressure worse, which can increase your risk of having a heart attack or stroke.
For people with stomach ulcer or bleeding: Meloxicam can make these conditions worse. If you have a history of these conditions, you have a higher chance of having them again if you take this medicine.
For people with liver damage: Meloxicam can cause liver disease and changes in your liver function. It may make your liver damage worse.
For people with kidney disease: If you take meloxicam for a long time, it may decrease your kidney function, making your kidney disease worse. Stopping this drug could reverse kidney damage caused by the drug.
For people with asthma: Meloxicam can cause bronchial spasm and difficulty breathing, especially if your asthma gets worse if you take aspirin.
Warnings for other groups
For pregnant women: Using meloxicam during your third trimester of pregnancy increases the risk of negative effects to your pregnancy. You should not take meloxicam after 29 weeks of pregnancy. If you’re pregnant, talk to your doctor. Meloxicam should be used during pregnancy only if the potential benefit justifies the potential risk.
You should also talk to your doctor if you’re trying to get pregnant. Meloxicam can cause a reversible delay in ovulation. If you’re having a hard time getting pregnant or are getting tested for infertility, don’t take meloxicam.
For women who are breastfeeding: It isn’t known if meloxicam passes into breast milk. If it does, it could cause side effects in your child if you breastfeed and take meloxicam. You and your doctor may decide whether you’ll take meloxicam or breastfeed.
For seniors: If you’re aged 65 years or older, you may have a higher risk of side effects from meloxicam.
How to take meloxicam
This dosage information is for meloxicam oral tablet. All possible dosages and forms may not be included here. Your dose, form, and how often you take it will depend on:
- your age
- the condition being treated
- how severe your condition is
- other medical conditions you have
- how you react to the first dose
Forms and strengths
- Form: Oral tablet
- Strengths: 7.5 mg, 15 mg
- Form: Oral tablet
- Strengths: 7.5 mg, 15 mg
- Form: Oral suspension
- Strength: 7.5 mg/ 5 mL
- Form: Oral capsule
- Strengths: 5 mg, 10 mg
Dosage for osteoarthritis
Adult dosage (ages 18 years and older)
- The initial dose is 7.5 mg taken once per day.
- Your doctor may increase your dose to a maximum of 15 mg per day.
Child dosage (ages 0-17 years)
Dosage for people younger than 18 years hasn’t been established.
Dosage for rheumatoid arthritis
Adult dosage (ages 18 years and older)
- The initial dose is 7.5 mg taken once per day.
- The dose may be increased to a maximum of 15 mg per day.
Dosage for juvenile rheumatoid arthritis
Child dosage (ages 2-17 years)
- The initial dose is usually 0.125 milligram per kilogram of body weight taken once per day.
- The maximum dose is 7.5 milligrams per day.
- The oral liquid form of this drug may be preferred for small children.
Child dosage (ages 0-1 years)
Dosage for children younger than 2 years hasn’t been established.
This drug isn’t removed in dialysis. Taking a usual dose of meloxicam while receiving hemodialysis may cause a buildup of the drug in your blood. This could cause worsened side effects. The maximum daily dose for people aged 18 years and older and receiving hemodialysis is 7.5 milligrams per day.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.
Take as directed
Meloxicam oral tablet may be used for short-term or long-term treatment. It comes with risks if you don’t take it as prescribed by your doctor.
If you take too much: Taking extra meloxicam can cause the serious side effects. This may include nausea, vomiting, stomach pain, and stomach bleeding. Overdosing on meloxicam can cause organ failure or serious heart problems. If you take or think you’ve taken too much meloxicam, get medical help right away.
What to do if you miss a dose: If you miss a dose, take it as soon as you can, However, if it’s just a few hours until your next dose, skip the missed dose and take the next one on time.
Never try to catch up by taking two doses at once. This could result in serious side effects.
How to tell if the drug is working: You may be able to tell if this drug is working if you experience less pain and inflammation.
Important considerations for taking meloxicam
Keep these considerations in mind if your doctor prescribes meloxicam oral tablet for you.
- You can take meloxicam with or without food. If it upsets your stomach, take it with food or milk.
- You can cut or crush the oral tablet.
- Store this medication at room temperature, 77°F (25°C).If needed, you can keep it for short periods at temperatures between 59°F and 86°F (15°C and 30°C).
- Make sure not to freeze the suspension.
- Keep this medication away from high temperatures.
- Meloxicam capsules should be kept in their original container. Keep all containers that contain meloxicam tightly closed.
- Keep your medications away from areas where they could get damp, such as bathrooms.
A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.
When traveling with your medicine:
- Always carry it with you or in your carry-on bag.
- Don’t worry about airport X-ray machines. They can’t hurt this drug.
- You may need to show your pharmacy’s preprinted label to identify the drug. Keep the original prescription-labeled box with you when traveling
Your doctor may check your:
- blood pressure
- liver function
- kidney function
- red blood cell count to check for anemia
Before they approve the prescription and pay for this drug, many insurance companies require prior authorization for the brand version and for use in children younger than 12 years old.
Are there any alternatives?
There are other medicines available to treat your condition. Some may be more suitable for you than others. Talk to your doctor about possible alternatives.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.