We’ve carefully selected these lupus nonprofits because they’re actively working to educate, inspire, and support people living with lupus and their loved ones. Nominate a notable nonprofit by emailing us at nominations@healthline.com.

Lupus is a chronic disease that affects at least 161,000 people in the United States alone. An autoimmune disease, it triggers inflammation throughout the body and can affect the joints, skin, lungs, and more. This can cause pain, fatigue, and sometimes even death.

Lupus can be difficult to diagnose, and some people live with the symptoms of the disease for years before knowing the real story behind their medical problems. While early diagnosis can lead to more effective treatments, these treatments often cause side effects nearly as unpleasant as the disease itself.

These top lupus nonprofits are all striving to make a difference in the lives of those affected by this disease.

Lupus Foundation of America

The Lupus Foundation of America works to ensure that people with lupus have access to effective and safe treatment, and to reduce the time it takes for people to receive a diagnosis. The foundation has chapters across the country, each contributing to the national level goals and supporting people with lupus in their communities. Their website is a valuable resource and includes a page all about how you can get involved — such as by writing to your lawmakers, participating in clinical trials, raising money, taking part in fundraising walks, and becoming a lupus advocate.

Tweet them @LupusOrg

Lupus Research Alliance

The Lupus Research Alliance, based in New York City, works to raise money to support scientists working to improve treatments and reach for a lupus cure. They believe that well-funded research is the best way they can support the many people living with this disease. Their website has many useful tools, including information on all of their efforts and even links to resources providing financial assistance to people living with lupus.

Tweet them @LupusResearch 

Lupus Foundation of Northern California

Founded in 1978 as the Bay Area Lupus Foundation, the Lupus Foundation of Northern California is a well-known organization with a storied reputation. They strive to provide those with lupus in California with access to social, educational, and medical resources in multiple languages. They hold conferences, support groups, and match people in a Lupus Buddy Program. We love that they offer the option to subscribe to their updates via text message, making staying informed easy and accessible.

Tweet them @LFNC

Lupus Canada

One in 1,000 Canadians lives with lupus, according to Lupus Canada. This organization strives to bring those people together under one roof, where they can get access to educational materials, resources for treatment, and support from people who know what it’s like to live with this disease. Their site is filled with many useful tools including lupus-friendly recipes and links to research updates. We particularly appreciate their catalog of educational videos, featuring both personal stories and informational summaries.

Tweet them @LupusCanada

World Lupus Day

More than five million people across the globe live with lupus. World Lupus Day brings together lupus organizations from all over, each with similar missions of raising awareness, improving access to treatments, and funding lupus research. In 2017, the World Lupus Federation celebrated the 14th annual World Lupus Day, an opportunity for people from different cultures, ethnicities, genders, and nationalities to get together for a common cause. Their website is not only an interactive flyer for this annual event, but a useful resource for anyone affected by the disease.

Tweet them @worldlupusday