Advertisement

Latanoprost, Ophthalmic Solution

Highlights for latanoprost

  1. Latanoprost ophthalmic solution is available as a generic drug and a brand-name drug. Brand name: Xalatan.
  2. This drug is only available as an ophthalmic solution (eye drop).
  3. Latanoprost is used to treat open-angle glaucoma and ocular hypertension.
Advertisement
Advertisement

Important warnings

Important warnings

  • Darkening of your eyes and lashes: This drug can darken the color of your eye or change it from a light color to brown. It can also cause the skin around your eye to darken. It may cause your eyelashes to grow longer, thicker, and darker in color. These changes often occur slowly, but they can be permanent. If you only use this drug in one eye, your eyes may look different from each other. Call your doctor if you have these changes.
  • Contact lenses: If you wear contact lenses, you should remove them from your eyes before using this drug. Wait at least 15 minutes after using your eye drops before you put your contacts in your eyes again.
  • Contamination of dropper tip and solution: Be careful not to let the dropper tip of the eye drops touch your eye, eyelids, or surrounding areas when giving yourself the medication. This could contaminate the dropper tip and the solution and lead to infection.
  • Eye problems: This drug may cause macular edema. In this condition, fluid builds up in your eye and causes it to swell. This can damage your vision. You’re at higher risk of this side effect if you have a history of macular edema or other eye problems. Talk to your doctor before using latanoprost if you have a history of eye problems.

About

What is latanoprost?

Latanoprost is a prescription drug. It comes as an ophthalmic solution (eye drop).

Latanoprost is available as the brand-name drug Xalatan. It’s also available as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version.

Latanoprost may be used as part of a combination therapy. This means you may need to take it with other medications.

Why it's used

Latanoprost is used to treat open-angle glaucoma and ocular hypertension. These conditions are caused by an increase in pressure in your eye. They may cause eye pain or vision changes.

How it works

Latanoprost belongs to a class of drugs called prostaglandin inhibitors. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Latanoprost works by lowering the pressure in your eyes. It does this by helping to increase the natural flow of fluids out of your eye.

Advertisement
Advertisement
Advertisement

Side effects

Latanoprost side effects

Latanoprost ophthalmic solution can cause certain side effects.

More common side effects

The more common side effects of latanoprost can include:

  • changes in your eye color
  • changes in the thickness, length, or color of your eyelashes
  • darkening of the skin around your eyes
  • blurred vision
  • burning or stinging
  • dry eyes

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • Sensitivity to light
  • Eye pain or irritation
  • Trouble seeing or vision loss
  • Pink eye. Symptoms can include:
    • eye itching or redness
    • eye tearing or crusting
  • Redness or swelling of your eyes

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we can not guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

Interactions

Latanoprost may interact with other medications

Latanoprost ophthalmic solution can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Examples of drugs that can cause interactions with latanoprost are listed below.

Drugs that cause more side effects

Taking latanoprost with certain drugs may cause more side effects. These drugs include:

  • Other eye drops. You shouldn’t use latanoprost with eye drops that have an ingredient called thimerosal in them. Using these eye medications together can cause side effects. If you use more than one eye drop, wait at least 5 minutes between using each drug.
  • Prostaglandin analogs. You should not use latanoprost with other prostaglandin analogs. Using these types of eye medications more than once a day may cause the pressure in the eye to increase. These drugs include:
    • bimatoprost
    • tafluprost
    • travoprost

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we can not guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

Advertisement
Advertisement

Other warnings

Latanoprost warnings

This drug comes with several warnings.

Allergy warning

Latanoprost can cause a severe allergic reaction. Note that this drug contains benzalkonium chloride. If you’re allergic to benzalkonium chloride, you shouldn’t use latanoprost.

Symptoms of an allergic reaction can include:

  • trouble breathing
  • swelling of your throat or tongue

If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 911 or go to the nearest emergency room.

Don’t take this drug again if you’ve ever had an allergic reaction to it or to benzalkonium chloride. Taking it again could be fatal (cause death).

Warning for pregnant women

Latanoprost is a category C pregnancy drug. That means two things:

  1. Research in animals has shown adverse effects to the fetus when the mother takes the drug.
  2. There haven’t been enough studies done in humans to be certain how the drug might affect the fetus.
When to call the doctor

Call your doctor if you:

  • become pregnant while taking this drug.
  • have any changes in your vision, very red eyes, or pain in or around your eyes.
  • develop an eye infection or injure your eye.
  • need to have any type of eye surgery.

Talk to your doctor if you’re pregnant or planning to become pregnant. This drug should only be used if the potential benefit justifies the potential risk to the fetus.

Call your doctor if you become pregnant while taking this drug.

Warning for women who are breastfeeding

It’s unlikely that this drug would pass into breast milk. Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

Warning for children

This medication hasn’t been studied in children. It shouldn’t be used in people younger than 18 years.

Advertisement

Dosage

How to take latanoprost

All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

Drug forms and strengths

Generic: Latanoprost

  • Form: ophthalmic solution
  • Strength: 0.005%

Brand: Xalatan

  • Form: ophthalmic solution
  • Strength: 0.005%

Dosage for open-angle glaucoma

Adult dosage (ages 18 years and older):

Place one drop in the affected eye(s) once per day in the evening.

Child dosage (ages 0–17 years):

This medication hasn’t been studied in children. It shouldn’t be used in people younger than 18 years.

Dosage for ocular hypertension

Adult dosage (ages 18 years and older):

Place one drop in the affected eye(s) once per day in the evening.

Child dosage (ages 0–17 years):

This medication hasn’t been studied in children. It shouldn’t be used in people younger than 18 years.

Dosage warnings

If you need to use a second eye medication, wait at least 5 minutes before putting the second drug in your eye. Don’t use this drug more than once per day. If you use it more often, it won’t be as effective at treating your condition.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we can not guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.

Advertisement
Advertisement

Take as directed

Take as directed

Latanoprost is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed.

If you stop taking the drug or don’t take it at all: The pressure level in your eyes may rise. If your eye pressure level is high and not controlled for a long time, you can have serious complications. These include vision loss.

If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.

If you take too much: If you take too much, you could also have dangerous levels of the drug in your body. Symptoms may include:

  • eye irritation
  • redness

If you think you’ve taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room right away.

What to do if you miss a dose: If you miss your dose, take your next dose as scheduled. Never try to catch up by taking two doses at once. Don’t use this drug more than once a day. Using it more than once a day may cause it not to work as well to lower the pressure in your eyes.

How to tell if the drug is working: Your symptoms may get better. Latanoprost will help control glaucoma and ocular hypertension, but it doesn’t cure either disease. It’s important to keep using latanoprost even if you feel well. Your doctor will test the pressure in your eyes to see if the drug is working.

Important considerations

Important considerations for taking latanoprost

Keep these considerations in mind if your doctor prescribes latanoprost for you.

General

Latanoprost should be used once per day in the evening.

Storage

  • Store the unopened bottle of latanoprost in the refrigerator. Keep it at a temperature between 36°F and 46°F (2°C and 8°C).
  • Once a bottle is opened, this drug may be stored at room temperature. Keep it at 77°F (25°C) for up to 6 weeks.
  • Keep this drug away from light.

Refills

A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

  • Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
  • Don’t worry about airport x-ray machines. They won’t damage your medication.
  • You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled box with you.
  • Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.

Self-management

Your doctor, nurse, or pharmacist will show you how to instill (give yourself) latanoprost eye drops.

If you wear contact lenses, you should remove them from your eyes before using this drug. Wait at least 15 minutes after using your eye drops before you put your contacts in your eyes again.

Clinical monitoring

During your treatment with latanoprost, your doctor will monitor your eye pressure level. This is done to make sure your level is within the range your doctor feels is best for you. It will also tell if your medication is working.

This monitoring may be done using a test called tonometry. This test involves blowing a puff of air into your eyes, or an instrument is used to touch the surface of your eyes.

Availability

Not every pharmacy stocks this drug. When filling your prescription, be sure to call ahead to make sure they carry it.

Prior authorization

Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription.

Advertisement
Advertisement
Advertisement

Alternatives

Are there any alternatives?

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained here in is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

Advertisement
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement