You may have heard that you have high cholesterol, high triglycerides, low HDL cholesterol, or even a high level of lipids in your blood.

You may have also heard of hyperlipidemia and hypercholesterolemia and wondered if these conditions are the same and how they relate to your cholesterol or triglyceride levels.

Hypercholesterolemia is a specific type of hyperlipidemia. The two conditions have many common factors, but there are also some differences.

Read on to learn more about the differences between the two, as well as the risk factors, potential complications, and treatments for these conditions.

Hyperlipidemia is a condition where you have a high level of lipids (fats) in your blood. Specifically, with hyperlipidemia, you have high levels of the following types of lipids:

  • Low-density lipoprotein (LDL) cholesterol. LDL cholesterol is often referred to as the “bad” cholesterol. It plays a key role in the buildup of fatty deposits in arteries, causing them to narrow (atherosclerosis).
  • Triglycerides. When you take in more calories than you burn, your body converts the excess calories into triglycerides, a type of fat. Having high triglyceride levels plus high LDL may increase the risk of plaque buildup in your arteries.

Hyperlipidemia is a common condition. It’s estimated that 50 percent of Americans have hyperlipidemia in some form.

What’s considered a high level of cholesterol and triglycerides?

A blood test called a lipid panel, or a lipid profile, can determine your cholesterol and triglyceride levels. Levels are often measured in milligrams per deciliter (mg/dL).

According to the National Library of Medicine, your total cholesterol, LDL cholesterol, and triglycerides can be classified as follows:

Total CholesterolLDLTriglycerides
NormalUnder 200 mg/dLUnder 100 mg/dLUnder 150 mg/dL
Near optimal/above optimaln/a100–129mg/dLn/a
Borderline high201–239 mg/dL130–159 mg/dL150–199 mg/dL
HighOver 240 mg/dL160–189 mg/dL200–499 mg/dL
Very highOver 190 mg/dLOver 500 mg/dL

Causes and risk factors of hyperlipidemia

Hyperlipidemia can be genetic, meaning it runs in families and is an inherited condition. This type of hyperlipidemia is called primary hyperlipidemia, or familial hyperlipidemia.

But hyperlipidemia is more often the result of lifestyle factors, such as:

  • an unbalanced diet, especially one that’s high in saturated fat
  • too little physical activity
  • having overweight or obesity
  • smoking
  • heavy alcohol use

Other factors that can put you at an increased risk of hyperlipidemia, even if you don’t have other risk factors, include:

Hypercholesterolemia is a specific type of hyperlipidemia. With hypercholesterolemia, you either have too much LDL cholesterol or too little high-density lipoprotein (HDL) cholesterol in your blood.

High-density lipoprotein (HDL) cholesterol is also known as “good” cholesterol. This healthy type of cholesterol helps to remove LDL cholesterol — the “bad“ type — from your arteries. Because HDL cholesterol plays an important role in getting rid of LDL, you want higher levels of HDL in your blood.

The risk factors, potential causes, and possible health impacts are the same for hypercholesterolemia as they are for hyperlipidemia.

What’s considered a healthy level of HDL cholesterol?

A desirable level of HDL cholesterol is considered to be 60 mg/dL or above. A level of 40 mg/dL or lower (for males) and 50 mg/dL or lower (for females) is considered to put you at a higher risk of a heart attack and stroke.

Hypercholesterolemia is a type of hyperlipidemia. In other words, hyperlipidemia is an umbrella term. Various inherited or acquired disorders that cause high lipid levels in the blood fall under this umbrella category.

The key differences between hyperlipidemia and hypercholesterolemia can be summarized as follows:

Hypercholesterolemia vs. hyperlipidemia

  • Hyperlipidemia is above normal lipid (fat) levels in the blood, which include several types of lipids, including triglycerides.
  • Hypercholesterolemia is above normal levels of LDL or total cholesterol in your blood. It doesn‘t include triglycerides.
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Neither hyperlipidemia nor hypercholesterolemia cause symptoms in most people. That’s one reason why it’s important to get your cholesterol and triglyceride levels checked on a regular basis.

Your doctor may order a blood test called a lipid panel to check your lipid levels if you have certain risk factors or if you have a family history of either condition.

These tests are also often part of routine care after you reach a certain age — usually 35 years old for males and 45 years old for females, unless you have other risk factors.

You may need to fast for 9 to 12 hours before your blood test to get an accurate reading.

For many people with hyperlipidemia or hypercholesterolemia, lifestyle changes are enough to help manage their condition.

Lifestyle changes that may help reduce lipid or cholesterol levels include:

  • Reducing your intake of saturated fat and trans fat; this may include eating less:
    • red meat
    • whole milk dairy products
    • fried foods
    • processed foods
  • Eating more vegetables, fruits, whole grains, fish, skinless poultry, nuts, and seeds.
  • Exercising regularly. Aiming for at least 150 minutes of moderate-intensity exercise each week can help reap the most health benefits.
  • Losing weight if you have overweight or obesity.
  • Quitting smoking, if you smoke.
  • Cutting back on your alcohol intake.

If lifestyle changes aren’t enough to reduce your lipid or cholesterol levels, your doctor may consider prescribing medications as well.

Medications that may help manage hyperlipidemia or hypercholesterolemia include:

If left untreated, hyperlipidemia and hypercholesterolemia can both lead to serious health complications, including:

Hyperlipidemia is an umbrella term that includes various disorders that cause high lipid levels in the blood. Hypercholesterolemia is a type of hyperlipidemia that involves above normal levels of cholesterol in the blood.

By maintaining a moderate weight, eating a balanced diet, and exercising regularly, you may be able to help keep both cholesterol and other blood lipids under control and reduce your risk of a heart attack or stroke.

If you have any risk factors for either hyperlipidemia or hypercholesterolemia, talk with a doctor about getting your lipid levels checked.