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Hand, foot, and mouth disease (HFMD) is a highly contagious infection. It’s caused by viruses from the Enterovirus genus, most commonly the coxsackievirus.

These viruses can spread from person to person through direct contact with unwashed hands or surfaces contaminated with feces. It can also be transmitted through contact with a person’s infected saliva, stool, or respiratory secretions.

HFMD is characterized by blisters or sores in the mouth and a rash on the hands and feet. The infection can affect people of all ages, but it usually occurs in children under age 5.

It’s generally a mild condition that goes away on its own within several days.

The symptoms begin to develop 3 to 6 days after the initial infection. This period is known as the incubation period. When symptoms do appear, you or your child may experience:

A fever and sore throat are usually the first symptoms of HFMD. The characteristic blisters and rashes show up later, usually 1 or 2 days after the fever begins.

HFMD is often caused by a strain of coxsackievirus, most commonly coxsackievirus A16. The coxsackievirus is part of a group of viruses called enteroviruses. In some cases, other types of enteroviruses can cause HFMD.

Viruses can be easily spread from person to person. You or your child may get HFMD through contact with a person’s infected:

  • saliva
  • fluid from blisters
  • feces
  • respiratory droplets sprayed into the air after coughing or sneezing

HFMD can also be transmitted through direct contact with unwashed hands or a surface containing traces of the virus.

Young children have the highest risk for getting HFMD. Risk increases if they attend daycare or school, as viruses can spread quickly in these facilities.

Children usually build up immunity to the disease after being exposed to the viruses that cause it. This is why the condition rarely affects people over age 10.

However, it’s still possible for older children and adults to get the infection, especially if they have weakened immune systems.

A doctor can often diagnose HFMD simply by performing a physical exam. They’ll check the mouth and body for the appearance of blisters and rashes. The doctor will also ask you or your child about other symptoms.

The doctor may take a throat swab or stool sample that can be tested for the virus. This will allow them to confirm the diagnosis.

In most cases, the infection will go away without treatment in 7 to 10 days. However, your doctor may recommend certain treatments to help ease symptoms until the disease has run its course. These can include:

  • prescription or over-the-counter topical ointments to soothe blisters and rashes
  • pain medication, such as acetaminophen or ibuprofen, to relieve headaches
  • medicated syrups or lozenges to ease painful sore throats

Aspirin shouldn’t be given to children for viral infections. Aspirin can lead to Reye’s syndrome in children.

Certain at-home treatments can also provide relief from HFMD symptoms. You can try the following home remedies to help make blisters less bothersome:

  • Suck on ice or popsicles.
  • Eat ice cream or sherbet.
  • Drink cold beverages.
  • Avoid citrus fruits, fruit drinks, and soda.
  • Avoid spicy or salty foods.

Swishing warm saltwater around in the mouth may also help relieve the pain associated with mouth blisters and throat sores. Do this several times a day or as often as needed.

You or your child should feel completely better 7 to 10 days after the initial onset of symptoms. Reinfection is uncommon. The body usually builds up immunity to the viruses that cause the disease.

Call a doctor immediately if symptoms get worse or don’t clear up within 10 days. In rare cases, coxsackievirus can cause a medical emergency.

Potential complications of HFMD include:

Practicing good hygiene is the best defense against HFMD. Regular handwashing can greatly reduce your risk for contracting this virus.

Teach your children how to wash their hands using hot water and soap. Hands should always be washed after using the restroom, before eating, and after being out in public. Children should also be taught not to put their hands or other objects in or near their mouths.

It’s also important to disinfect any common areas in your home on a regular basis. Get in the habit of cleaning shared surfaces first with soap and water, then with a diluted solution of bleach and water. You should also disinfect toys, pacifiers, and other objects that may be contaminated with the virus.

If you or your child experience symptoms such as a fever or sore throat, stay home from school or work. You should continue avoiding contact with others once the telltale blisters and rashes develop. This can help you avoid spreading the disease to others.