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The best full-spectrum CBD tinctures for your needs can depend on the level of potency and price point you prefer. Read on for our picks of the best tinctures, how to shop, and more.

Healthline has sole editorial control over this article. Potential uses for the products listed here are not health claims made by the manufacturers. The information in this article is intended to be general in nature. It’s not intended to be a substitute for medical advice from a healthcare professional. Healthline encourages you to make any treatment decisions with your healthcare professional.

If you’re on the hunt for a great CBD product, you may have noticed that you have lots of choices. Not only are there different types of products — including oils, gummies, lotions, and even beauty products — but there are also different types of CBD.

Although CBD isolate, broad-spectrum CBD, and full-spectrum CBD each have their own unique qualities, full-spectrum CBD is the only one that has all compounds of the cannabis plant, including both cannabidiol (CBD) and tetrahydrocannabinol (THC). That may make it particularly beneficial, thanks to what is known as the entourage effect.

Read on to learn more about the benefits of full-spectrum CBD and get our take on some of the best full-spectrum CBD tinctures and oils out there.

While the term “CBD tincture” is often used interchangeably with “CBD oil,” the two are actually different.

Tinctures are made by soaking cannabis in alcohol, while oils are made by suspending CBD in a carrier oil like olive oil or coconut oil.

In our search for the best CBD tinctures, we’ve found that many brands have CBD oils for sale that are actually labeled as CBD tinctures.

We continue to actively search for true tinctures that meet our vetting standards. At this time, the products that meet our requirements are oils. So, we chose the oils on this page for their flavor, effect, and quality. You’ll notice that some products are labeled as tinctures, but all are, in fact, CBD oils.

Read more about CBD tinctures versus CBD oils.

We chose these products based on criteria that the manufacturers are prioritizing safety and quality and are honest about their products.

Each product in this article:

  • is made by a company that provides proof of third-party testing by an ISO 17025-compliant lab
  • is made by a company that’s transparent about where its hemp is grown
  • contains no more than 0.3% THC, according to the certificate of analysis (COA)
  • passes tests for pesticides, heavy metals, and molds, according to the COA

We also considered:

  • certifications and manufacturing processes
  • product potency
  • overall ingredients
  • indicators of user trust and brand reputation, such as:

ProductPriceCBD per bottle
Aspen Green Bliss Full-Spectrum CBD Oil$1393,350 mg per 30-mL bottle
Cornbread Hemp Whole Flower CBD Oil$751,500 mg per bottler 30-mL bottle
CBDfx Calming Tincture$69.991,000 mg per 30-mL bottle
Lazarus Naturals High Potency CBD Tincture$401,500 mg per 30-mL bottle
CBDistillery Full Spectrum CBD Oil Tincture$701,000 mg per 30-mL bottle

The entourage effect is a theory that CBD works better when it’s combined with other parts of the cannabis plant. That can include other cannabinoids (like THC), terpenes, and flavonoids.

While research is ongoing, some studies support this theory.

A 2018 study compared the effects of CBD-rich cannabis extracts and CBD isolate extracts in people with refractory epilepsy. Participants appeared to respond better with CBD-rich cannabis extracts at a lower dosage than they did with purified or CBD isolate extracts.

The study authors believed the mixture of CBD and THC created an entourage effect, resulting in a more potent extract.

Full-spectrum CBD is unique because it’s the only type of CBD that contains everything found in the cannabis plant. That means that if you’re looking to reap the benefits of the entourage effect, it may be the best choice.

There are a lot of claims about the benefits of CBD. Apart from anecdotal evidence, here’s what research backs up.

Pain management

There are multiple studies that link CBD with improved pain management. A 2018 review of studies examining cannabis (including both CBD and THC) and pain between 1975 and early 2018 concluded that CBD may help relieve pain related to cancer, neuropathy, and fibromyalgia.

Similarly, a 2020 review noted that animal studies have shown CBD to relieve pain and inflammation. However, it cautions that more human studies are needed to confirm CBD’s effects.

Anxiety and sleep

Research from 2019 reviewed CBD’s efficacy for anxiety and sleep. The study looked at the effects of 25 mg of CBD per day in 72 adults, with 79.2% reporting lower anxiety levels and 66.7% experiencing better sleep after 4 weeks of use.

Other studies indicate CBD may help moderate anxiety during public speaking and reduce anxiety levels overall.

Keep in mind that even though CBD shows promise as a complementary treatment for certain conditions, as well as for helping people sleep better and manage pain, it still requires more research.

There’s only one FDA-approved CBD medication, which is approved to treat two types of seizures associated with epilepsy. Currently, there are no FDA-approved over-the-counter (OTC) CBD products, and the FDA doesn’t regulate CBD the same way it does supplements and other OTC medications.

That’s why it’s important to do research to find the best quality CBD products.

The first thing you’ll want to do is check for a COA. This should be from a reputable third-party lab, and it should be up to date — usually no more than 12 months old.

You can use the COA to verify that the product actually contains the amount of CBD and THC as the label says it does. The COA will also tell you whether the product has passed contaminant testing.

Additionally, look for a company that’s transparent about how it makes its products and where it sources its hemp. The more information it can provide you, the better.

If you’re still uncertain about whether you can trust a brand, browse reviews, and do a Google search to see whether it’s been involved in any lawsuits. Another warning sign is if the company is making false health claims and has been sent an FDA warning letter.

CBD exists in various forms. You’ve probably seen it in oils, tinctures, creams, pills, and gummies.

While pills and gummies are pretty self-explanatory, tinctures can be a little more mystifying. But don’t worry — they’re easy to use. You can add them to food or drinks, or you can place them under your tongue and hold them there for up to 1 minute before swallowing.


Figuring out the right dosage for you will depend on:

  • your body weight
  • the concentration of the CBD you’re taking
  • the reason you’re taking it

Make sure to follow the directions on the bottle. If you’re uncertain, it’s best to be cautious and take the smallest dosage recommended. Once you understand how your body reacts to this amount, you can gradually increase it over time.

CBD is generally considered safe. But it’s still important to take precautions and discuss any medications, vitamins, or supplements you’re taking with your doctor. Some medications can negatively interact with CBD.

In rare circumstances, some people may experience side effects from CBD. These can include:

  • fatigue
  • diarrhea
  • changes in appetite
  • changes in weight

Avoid ingesting CBD with higher fat meals. A 2020 study found that there was an increased risk of higher CBD concentrations in the bloodstream when CBD was taken with a high fat meal. This can increase your chances of side effects.

If you’re pregnant or breastfeeding, don’t take CBD.

People use full-spectrum CBD tincture for all sorts of issues, ranging from pain to anxiety and more. While limited research shows that it may be helpful, more research is needed to say for sure.

CBD tinctures range from low potency (less than 15 mg per mL) to high potency (more than 50 mg per mL). You can find CBD oils with as much as 100 mg of CBD per mL of product.

The difference is in the way each product is made. While CBD oils are made by extracting CBD through carbon dioxide extraction and then infusing it in a carrier oil, CBD tinctures are made by soaking CBD in alcohol.

Full-spectrum CBD does contain THC, the compound associated with feeling “high.” But by federal law, it must be in very small amounts (less than 0.3%).

For most people, that’s not enough to feel intoxicated. However, those effects can depend on a product’s potency and how much you consume at one time. A large enough dose of a very potent product could be enough to produce a euphoric effect.

Both full and broad-spectrum CBD contain various components from the cannabis plant, including different cannabinoids and terpenes. But while full-spectrum CBD contains up to 0.3% THC, broad-spectrum CBD contains no THC.

If you want to avoid THC in a CBD product, even in low amounts, look for broad-spectrum or isolate products.

A 2014 study that looked at the impact of medical cannabis in the treatment of neurological conditions found a possible link between higher levels of THC and anxiety.

Other evidence suggests cannabis may help relieve symptoms of depression and anxiety.

More research is needed for a definitive answer, but if you’re prone to anxiety, you may want to explore CBD options without THC, like broad-spectrum or isolate products.

Yes, it’s possible for the THC in a full-spectrum CBD product to show up on a drug test.

Whether it’s your first time taking CBD or you have experience, it’s helpful to be well informed about the products you buy. Look for a tincture that comes with a clear, comprehensive COA.

If you take any medications, be sure to consult your doctor before adding CBD to your regimen.

Is CBD legal? The 2018 Farm Bill removed hemp from the legal definition of marijuana in the Controlled Substances Act. This made some hemp-derived CBD products with less than 0.3% THC legal at the federal level. However, CBD products containing more than 0.3% THC still fall under the legal definition of marijuana, making them illegal at the federal level. Some states have legalized CBD, so be sure to check state laws, especially when traveling. Also, keep in mind that the FDA has not approved nonprescription CBD products, and some products may be inaccurately labeled.