Vabysmo (faricimab-svoa) is a prescription drug designed to treat certain types of eye conditions. Your dosage and dosing schedule depend on the condition the drug is prescribed to treat.
Vabysmo is prescribed to adults to help treat:
- diabetic macular edema (DME)
- neovascular (wet) age-related macular degeneration (AMD)
- macular edema from retinal vascular occlusion (a blockage in veins in your retina)
The active ingredient in Vabysmo is faricimab-svoa. Vabysmo is a biologic drug made from living cells. It belongs to a group of drugs called vascular endothelial growth factor and angiopoietin-2 inhibitors.
This article describes the dosages of Vabysmo, as well as its strength and how it’s given. To learn more about Vabysmo, see this in-depth article.
This section describes the usual dosages of Vabysmo. Keep reading to learn more.
What’s Vabysmo’s form?
Vabysmo is available as a liquid solution for injection into your eye by a healthcare professional.
What strength does Vabysmo come in?
Vabysmo comes in one strength of 120 milligrams (mg) per milliliter (mL) of solution in single-dose vials. Each single-dose vial contains 6 mg (0.05 mL of 120 mg per mL solution).
What are the usual dosages of Vabysmo?
How often Vabysmo is given depends on the condition the drug is prescribed to treat and your response to the medication. Your doctor will prescribe the recommended dosage to treat your condition.
The information below describes dosages that are commonly prescribed or recommended. In some cases, your doctor may adjust your dosage from those shown below.
Dosage for DME
For adults with DME, there are two dosing options for Vabysmo.
You may receive 6 mg (0.05 mL of 120 mg per mL solution) given as an injection into your eye by a healthcare professional once every 4 weeks for the first four doses. Then, your doctor will check your eyes with an optical coherence tomography (OCT) scan. If your condition improves after four doses of Vabysmo, your doctor may adjust your dosing schedule to every 8 weeks.
The other option for a dosing schedule for DME is 6 mg (0.05 mL of 120 mg per mL solution) given as an injection into your eye by a healthcare professional once every 4 weeks for the first six doses. Then, you’ll receive 6-mg doses once every 8 weeks.
In some cases, your doctor may give doses of Vabysmo once every 4 weeks. However, doses given every 4 weeks weren’t more effective than doses given every 8 weeks.
If you have questions about your Vabyysmo dosage or dosing schedule, talk with your doctor.
Dosage for wet AMD
The typical Vabysmo dosage for adults with wet AMD is 6 mg (0.05 mL of 120 mg per mL solution) given once every 4 weeks for the first four doses. You’ll be given Vabysmo as an injection into your eye by a healthcare professional.
After your first four doses, your doctor will check your eyes with an OCT scan at 8 and 12 weeks.
Based on the OCT scan, you may receive a Vabysmo 6-mg injection once every:
- 8 weeks at weeks 20, 28, 36, and 44
- 12 weeks at weeks 24, 36, and 48
- 16 weeks at weeks 28 and 44
In certain situations, your doctor may give 6-mg doses of Vabysmo every 4 weeks. But in studies, doses given every 4 weeks weren’t more effective than doses given every 8 weeks.
Talk with your doctor if you have questions about Vabysmo dosage and dosing schedule.
Dosage for macular edema from retinal vascular occlusion
The dosage of Vabysmo in adults with macular edema from retinal vascular occlusion is 6 mg (0.05 mL of 120 mg per mL solution) given as an injection into your eye every 4 weeks for 6 months.
Is Vabysmo prescribed long term?
Yes, Vabysmo is usually prescribed as a long-term treatment. If you and your doctor determine that it’s safe and effective for your condition, you’ll likely receive it long term.
Vabysmo is given as an intravitreal injection (injection into your eye). Specifically, it’s given into the vitreous fluid (the space between your lens and retina) of your eye.
The drug is given by a healthcare professional. You’ll be given your Vabysmo injection at your doctor’s office or healthcare facility.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.