If you’re looking at treatment options for gallstones or for primary biliary cholangitis (PBC), you may want to learn more about ursodiol (Actigall, Urso 250, Urso Forte).

Ursodiol is a generic prescription drug that’s used in the following situations:

  • dissolving gallstones in adults who can’t or don’t want to have gallbladder surgery
  • helping prevent gallstones from forming in adults with obesity who are experiencing rapid weight loss
  • treating PBC (a type of liver disease) in adults

Ursodiol belongs to a group of drugs called bile acids. These drugs work by helping dissolve gallstones.

Keep reading for details on ursodiol and cost, and how to save money on prescriptions.

Note: For more details on ursodiol, talk with your doctor or pharmacist.

The price you pay for ursodiol can vary. Your cost may depend on your treatment plan, your insurance coverage, and the pharmacy you use.

To find out how much you’ll pay for ursodiol, talk with your doctor, pharmacist, or insurance provider.

Below are answers to some frequently asked questions about ursodiol and cost.

Is ursodiol available over the counter?

No, ursodiol isn’t available over the counter (OTC). You can only get ursodiol with a prescription from your doctor.

OTC medications, such as acetaminophen (Tylenol) or ibuprofen (Advil, Motrin), may help with gallbladder pain. But there isn’t an OTC drug that can treat gallstones or primary biliary cholangitis.

Does ursodiol’s cost depend on whether I take tablets (250 mg or 500 mg) or capsules (300 mg)?

Yes, the form you take may increase the price you pay for ursodiol. Typically, ursodiol capsules cost more than the tablets. The price may also increase for higher strengths of the drug.

To learn what you may pay for the form and strength of ursodiol you’ve been prescribed, talk with your doctor or pharmacist.

How much does ursodiol cost without insurance?

The price of ursodiol without insurance can depend on several factors. For example, the cost may depend on the form or strength you’re taking. The pharmacy you choose can also affect the cost.

For more details on what you may pay for ursodiol without insurance, talk with your doctor or pharmacist. Also, see the “Can I get help paying for ursodiol?” section below for resources that may help with the cost of your prescription.

Generic ursodiol is available in brand-name versions called Actigall, Urso 250, Urso Forte. A generic drug is an exact copy of the active drug in a brand-name medication. The generic is considered to be just as safe and effective as the original drug. And generics tend to cost less than brand-name drugs.

To find out how the costs of Actigall, Urso 250, Urso Forte, and ursodiol compare, talk with your doctor, pharmacist, or insurance provider.

If your doctor has prescribed ursodiol and you’re interested in taking one of the brand-name drugs instead, talk with your doctor. They may have a preference for one version or the other. In addition, you’ll need to check with your insurance provider. This is because it may only cover certain versions of the drug.

If you take ursodiol long term, you may be able to lower your costs in the following ways:

  • Look into getting a 90-day supply of your medication. You may be able to get a 90-day supply of ursodiol if approved by your insurance company. This could reduce your number of trips to the pharmacy and help lower the cost of ursodiol. If you’re interested in getting a 90-day supply of this drug, talk with your doctor or insurance provider.
  • Use a mail-order pharmacy to get your medication. Using a mail-order pharmacy might help lower your cost for ursodiol. Plus, you could get your medication without leaving home. Some Medicare plans may help cover the cost of mail-order drugs. You may also be able to get a 90-day supply of the drug through mail order. If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need help covering the cost of ursodiol or understanding your insurance, check out these websites:

On these sites, you can find insurance information, details on drug assistance programs, and links to savings cards and other services.

If you have questions about how you can pay for ursodiol, you may also want to talk with your doctor or pharmacist.

If you still have questions about the cost of ursodiol, talk with your doctor or pharmacist. They may be able to give you a better idea of what you’ll pay for this drug. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you’d pay for ursodiol.

Examples of questions you may want to ask your doctor or insurance provider include:

  • Are there other lower-cost drugs similar to ursodiol that could treat my condition?
  • What are my options if I can’t afford my medication?
  • Are there additional things that don’t cost money that I can do to help my condition (such as diet and lifestyle changes)?
  • Will my dosage of ursodiol affect the cost?

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.