If you have asthma or chronic obstructive pulmonary disease (COPD), your doctor might suggest Trelegy Ellipta as a treatment option. It’s a prescription drug used for long-term management of asthma and COPD in adults.

Trelegy Ellipta has three active ingredients. An active ingredient is what makes a drug work. These active ingredients and their drug groups are as follows:

  • fluticasone furoate, an inhaled corticosteroid
  • umeclidinium, an anticholinergic
  • vilanterol, a long-acting beta2 agonist

Trelegy Ellipta comes as a dry powder for inhalation.

This article describes the dosages of Trelegy Ellipta, as well as its strengths and how to take it. To learn more about Trelegy Ellipta, see this in-depth article.

Note: This article covers Trelegy Ellipta’s usual dosages, which are provided by the drugmaker. But when taking Trelegy Ellipta, always take the dosage that your doctor prescribes.

The information below describes typical dosages of Trelegy Ellipta.

Note: This chart highlights the basics of Trelegy Ellipta’s dosages. Be sure to read on for more detail.

asthma• 1 inhalation of 100 micrograms (mcg) fluticasone furoate/62.5 mcg umeclidinium/25 mcg vilanterol (100/62.5/25 mcg) once per day, or
• 1 inhalation of 200 mcg fluticasone furoate/62.5 mcg umeclidinium/25 mcg vilanterol (200/62.5/25 mcg) once per day
chronic obstructive pulmonary disease (COPD)• 1 inhalation of 100 mcg fluticasone furoate/62.5 mcg umeclidinium/25 mcg vilanterol (100/62.5/25 mcg) once per day

What is the form of Trelegy Ellipta?

Trelegy Ellipta comes as a dry powder for inhalation. You’ll inhale the drug using an inhaler device. (“Trelegy” is the drug, and “Ellipta” refers to the device you use to take the medication.)

What strengths does Trelegy Ellipta come in?

Trelegy Ellipta is available in two strengths. They are:

  • 100 mcg fluticasone furoate/62.5 mcg umeclidinium/25 mcg vilanterol (100/62.5/25 mcg)
  • 200 mcg fluticasone furoate/62.5 mcg umeclidinium/25 mcg vilanterol (200/62.5/25 mcg)

What are the usual dosages of Trelegy Ellipta?

For asthma, your doctor will likely start you on the lowest possible dosage of Trelegy Ellipta. They’ll monitor you to see how you respond to treatment. It’s possible that your doctor may start you on the higher dose if your symptoms are severe. Ultimately, your doctor will prescribe the right dosage to manage your symptoms.

For chronic obstructive pulmonary disease (COPD), the drugmaker provides only one dosage.

The information below describes dosages that are commonly used or recommended. But be sure to take the dosage your doctor prescribes for you. They’ll determine the best dosage to fit your needs.

Dosage for asthma

The drugmaker provides two recommended starting dosages of Trelegy Ellipta for asthma. They are:

  • one inhalation of 100/62.5/25 mcg taken once per day, or
  • one inhalation of 200/62.5/25 mcg taken once per day

Your starting dosage depends on the severity of your condition and other factors. These include how well treatment manages your condition. If the lower dosage doesn’t manage your symptoms, your doctor may increase it to the higher dosage.

The maximum dosage of Trelegy Ellipta is 200/62.5/25 mcg, which is taken once per day. If the maximum dosage doesn’t manage your symptoms, your doctor will likely discuss other treatments.

Dosage for chronic obstructive pulmonary disease (COPD)

The typical Trelegy Ellipta maintenance dosage for COPD is one inhalation of 100/62.5/25 mcg taken once per day. This is the maximum dosage approved for COPD.

If your symptoms are not managed with this dosage, your doctor may suggest using a rescue inhaler. This can help provide relief when you have shortness of breath. One example of a rescue inhaler is albuterol.

Is Trelegy Ellipta used long term?

Yes, Trelegy Ellipta is usually used as a long-term treatment. You and your doctor can discuss whether Trelegy Ellipta is safe and effective for your condition. If you agree that it is, you’ll likely take it long term.

Below are answers to some questions commonly asked about Trelegy Ellipta’s dosage.

Does Trelegy Ellipta 200/62.5/25 mcg cause different side effects compared with other strengths?

It’s possible that it could. Most side effects reported for both dosages of Trelegy Ellipta were similar. But each person’s response to treatment can differ. You may experience different side effects based on the severity of your condition. Your side effects also could differ if you have other health conditions or are taking other medications.

Ask your doctor or pharmacist if you have more questions about possible side effects of Trelegy Ellipta. You can also read this article to learn more.

Are there dosing instructions for Trelegy Ellipta?

Yes, the drugmaker has dosing instructions for the drug. You’ll use the inhaler that comes with your prescription to take doses. The dosing frequency of Trelegy Ellipta is once per day. That means you’ll take one inhalation per day.

The drugmaker’s site can help you learn more about how to use the device. Additionally, the “Instructions for Use” section in Trelegy Ellipta’s label has dosing instructions. When you first start treatment, your doctor or pharmacist can show you how to use your inhaler step by step.

How many doses are there per Trelegy Ellipta inhaler?

Each Trelegy Ellipta inhaler has 30 doses. When taking one inhalation per day as prescribed, each inhaler should last you 30 days.

It’s important to take Trelegy Ellipta daily to improve your symptoms long term.

Your pharmacist will show you how to use your inhaler correctly. They’ll also show you how to identify the number of doses left. This will help you avoid running out of medication.

The dosage of Trelegy Ellipta you’re prescribed will depend on certain factors. These include the condition you’re using the drug to treat and its severity.

If you take Trelegy Ellipta for asthma, your doctor may adjust your dosage. They’ll base this adjustment on the severity of your condition and how you respond to treatment.

Trelegy Ellipta has only one recommended dosage for chronic obstructive pulmonary disease (COPD). It is one inhalation of 100/62.5/25 mcg taken once per day. This is also the maximum dosage.

Your doctor or pharmacist will show you how to use the Trelegy Ellipta inhaler. You can also review step-by-step instructions from the drug’s manufacturer on how to use Trelegy Ellipta. The “Instructions for Use” section in Trelegy Ellipta’s label also has dosing instructions.

You’ll take one inhalation of Trelegy Ellipta once per day. Try to take your dose at the same time each day. This helps keep consistent levels of the drug in your body.

The corticosteroid in Trelegy Ellipta is an immunosuppressant. After inhalation, drug residue may be left inside the mouth or the back of your throat. If so, a fungus called Candida can grow, which can cause an infection called thrush. So, after using your inhaler, be sure to rinse your mouth with water, but do not swallow.

Do not use Trelegy Ellipta as a rescue inhaler for sudden symptoms of asthma or chronic obstructive pulmonary disease (COPD). Trelegy Ellipta is a long-term treatment that helps manage your symptoms over time. If you experience life threatening symptoms, seek emergency medical help right away.

For information on the expiration, storage, and disposal of Trelegy Ellipta, see this article.

Accessible drug containers and labels

If you find it hard to read the prescription label on your medication, tell your doctor or pharmacist. Some pharmacies provide medication labels that:

  • have large print or use braille
  • feature a code you can scan with a smartphone to change the text to audio

Find out if your current pharmacy offers these accessibility features. If they don’t, your doctor or pharmacist may be able to recommend pharmacies that do.

If you miss a dose of Trelegy Ellipta, take it as soon as you remember. But if it’s almost time for your next dose, skip the missed dose. Then, take your next dose at its regularly scheduled time. Do not take more than one dose per day to make up for any missed doses. This could lead to serious side effects.

If you’re not sure whether to take a missed dose, ask your doctor or pharmacist.

If you need help remembering to take your dose of Trelegy Ellipta on time, try using a medication reminder. This can include setting an alarm or downloading a reminder app on your phone.

Trelegy Ellipta contains three active ingredients (fluticasone furoate, umeclidinium, and vilanterol). Taking too much of this medication can cause different reactions from these ingredients.

Do not take more Trelegy Ellipta than your doctor prescribes, as this can lead to serious side effects.

If you’ve taken too much Trelegy Ellipta, your doctor will monitor your heart. That’s because it’s possible to have serious heart problems if you take too much of the drug.

Symptoms of overdose

Fluticasone furoate overdose is unlikely. This is because it isn’t absorbed well into the body. It works mainly in the lungs.

Umeclidinium overdose can cause anticholinergic side effects, which may include:

  • blurry vision
  • decreased sweating
  • dry mouth or dry eyes
  • hallucinations
  • trouble urinating

Vilanterol overdose can cause serious symptoms, which may include:

In rare cases, vilanterol overdose may be fatal.

What to do in case you take too much Trelegy Ellipta

Call your doctor right away if you think you’ve taken too much Trelegy Ellipta. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource. But if you have severe symptoms, immediately call 911 (or a local emergency number) or go to the nearest emergency room.

The sections above describe the usual dosages provided by the drugmaker. If your doctor recommends Trelegy Ellipta for you, they’ll prescribe the dosage that’s right for you.

Remember, you should not change your dosage of Trelegy Ellipta without your doctor’s recommendation. Only take Trelegy Ellipta exactly as prescribed. Talk with your doctor if you have questions or concerns about your current dosage.

Here are some examples of questions you may want to ask your doctor:

  • If I have serious side effects, would my dosage be adjusted?
  • Will I need a lower dose of Trelegy Ellipta if I’m taking other asthma medications?
  • Should my dosage of Trelegy Ellipta change if it’s not managing my COPD?

To learn more about Trelegy Ellipta, see these articles:

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.