Spravato (esketamine) is prescribed to treat certain types of depression. Spravato’s cost may depend on factors such as your dosage and whether you have health insurance.

The price you pay for Spravato can vary. Your cost may depend on your treatment plan and your insurance coverage (if you have it). It also will depend on how much you have to pay for an office visit with your doctor to receive Spravato.

To find out how much you’ll pay for Spravato, talk with your doctor or insurance provider.

Below are answers to some frequently asked questions about Spravato and cost.

How much is Spravato without insurance?

What you’ll pay for Spravato without insurance depends on several factors. Generally, your cost will be higher without insurance.

Factors that could affect your cost include:

  • your treatment plan and dosage
  • whether you qualify for any savings programs
  • the supply of medication you receive (such as a 30-day or 90-day supply)

To find out the exact cost of Spravato without insurance, ask your doctor.

You can also visit Optum Perks for price estimates for many medications. (Optum Perks is a sister site of Healthline.) It’s important to note that Optum Perks coupons cannot be used with any insurance copays or benefits.

What is Spravato’s cost per dose?

To find out the cost of each dose of Spravato, you must know what you’ll pay for your Spravato prescription. Your cost for Spravato per dose will depend on whether you have drug coverage. The cost of each dose of Spravato also depends on how much you’ll pay to visit your doctor to receive your dose.

Speak with your doctor and insurance provider (if you have one). They can help you determine the cost of Spravato per dose.

What is Spravato’s cost with Medicare?

The cost of Spravato with Medicare depends on various factors. These include:

The cost also may depend on your dosage and other factors, such as your copay. A copay is your share of the cost of a medication.

To learn about the cost of Spravato with Medicare, talk with your Medicare insurance provider or your doctor. They can let you know what you can expect to pay for Spravato.

Spravato comes only as a brand-name drug. It’s not currently available in a generic version. A generic contains an exact copy of the active drug in a brand-name medication but tends to cost less.

Why is there such a cost difference between brand-name drugs and generics?

Years of research and testing are needed to ensure that brand-name drugs are safe and effective. This testing can make the drugs expensive. The manufacturer of a brand-name drug can sell the drug exclusively for up to 20 years. After that, other drugmakers can create generic versions. This competition in the market can lead to lower costs for generics. And because generics have the same active ingredients as brand-name drugs, they don’t need to be studied again. This also can lead to lower generic costs.

If you use Spravato long term, you may be able to lower your costs by using the drugmaker’s cost savings program.

If you need help covering the cost of Spravato or understanding your insurance, check out these resources:

On these pages, you can find insurance information, details on drug assistance programs, and links to savings cards and other services.

If you have questions about how to pay for your prescription, talk with your doctor.

If you have insurance, you may need to get prior authorization before your insurance provider will cover Spravato. This means your insurer and your doctor will discuss Spravato in regard to your treatment. Then the insurance company will determine whether the drug is covered. If Spravato requires prior authorization and you don’t receive it before you start treatment, you could pay the full cost of the drug.

Be sure to ask your insurance company whether Spravato requires prior authorization.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.