Sovaldi (sofosbuvir) is a prescription drug used in combination with other drugs to treat chronic hepatitis C virus (HCV). It comes as an oral tablet and pellets. It’s usually taken once daily.

Sovaldi is used to treat chronic (long lasting) HCV caused by certain genotypes (strains) of the virus.

  • For adults: Sovaldi is prescribed for HCV caused by genotypes 1, 2, 3, or 4, either without cirrhosis or with compensated cirrhosis.
  • For children ages 3 years and older: Sovaldi is prescribed for HCV caused by genotypes 2 or 3 without cirrhosis or with compensated cirrhosis.

The active ingredient in Sovaldi is sofosbuvir. Sovaldi belongs to a group of drugs called nucleotide polymerase inhibitors.

This article describes the dosages of Sovaldi, as well as its strengths and how to take it. To learn more about Sovaldi, see this in-depth article.

This section describes the usual dosages of Sovaldi Keep reading to learn more.

What are Sovaldi’s forms?

Sovaldi is available as an oral tablet. It’s also available in a pellet form for children who have difficulty swallowing tablets.

What strengths does Sovaldi come in?

Sovaldi tablets come in two strengths: 200 milligrams (mg) and 400 mg. Sovaldi pellets come in packets containing 150 mg or 200 mg.

What are the usual dosages of Sovaldi for adults?

The information below describes dosages that are commonly used or recommended. Be sure to take the dosage your doctor prescribes for you. They’ll determine the best dosage to fit your needs. In some cases, your doctor may adjust your dosage from those shown below.

Dosage for hepatitis C virus (HCV)

The recommended dosage of Sovaldi for adults with HCV is 400 mg taken once per day. The dose can be taken with or without food.

For adults with genotype 1 or 4, Sovaldi is prescribed along with peginterferon alfa and ribavirin. For adults with genotype 2 or 3, the drug is prescribed with ribavirin only.

What’s the dosage of Sovaldi for children?

Sovaldi is prescribed to treat HCV caused by genotype 2 or 3 in children ages 3 to 17 years. The dosage used in children is based on their body weight. Your child’s doctor will calculate the appropriate dosage for them.

When used in children, Sovaldi is prescribed along with ribavirin.

For more information about Sovaldi’s dosage for children, talk with your child’s doctor or a pharmacist.

Is Sovaldi used long term?

It depends. Sovaldi is usually prescribed for either 12 or 24 weeks only. However, people who are waiting for a liver transplant may be prescribed Sovaldi for up to 48 weeks. You can ask your doctor how long your treatment will likely last.

Do not take more Sovaldi than your doctor prescribes, as this can lead to harmful effects.

What to do in case you take too much Sovaldi

Call your doctor right away if you think you’ve taken too much Sovaldi. You can also call 800-222-1222 to reach America’s Poison Centers or use its online resource. But if you have severe symptoms, immediately call 911 (or your local emergency number) or go to the nearest emergency room.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.