Soliqua 100/33 (insulin glargine/lixisenatide) is a prescription drug that’s used to treat type 2 diabetes in adults. The drug’s cost may depend on factors such as your dosage, whether you have health insurance, and the pharmacy you use.

Soliqua 100/33 comes as a liquid solution inside single-use prefilled pens. You’ll inject the drug under your skin. The medication has two active ingredients: insulin glargine and lixisenatide. (An active ingredient is what makes a drug work.)

For more details on Soliqua 100/33, see this in-depth article.

The price you pay for Soliqua 100/33 can vary. Your cost may depend on your treatment plan, your insurance coverage (if you have it), and the pharmacy you use.

To find out how much you’ll pay for Soliqua 100/33, talk with your doctor, pharmacist, or insurance provider.

Note: If you have insurance, you may need to get prior authorization before your insurance provider will cover Soliqua 100/33. This means your insurer and your doctor will discuss Soliqua 100/33 in regard to your treatment. Then the insurance company will determine whether the drug is covered. If Soliqua 100/33 requires prior authorization and you don’t receive it before you start treatment, you could pay the full cost of the drug.

Be sure to ask your insurance company whether Soliqua 100/33 requires prior authorization.

Below are answers to some frequently asked questions about Soliqua 100/33 and cost.

Can Soliqua 100/33 be used for weight loss? If so, does it cost more for this use?

No, Soliqua 100/33 isn’t approved for weight loss. It’s approved only to manage blood sugar levels in people with type 2 diabetes.

However, you may experience weight loss during treatment with Soliqua 100/33 in some cases. For example, the medication is recommended for use along with a diet and exercise program. Eating a balanced diet and exercising may cause some people to lose weight.

Some people may also gain weight when using insulin, including Soliqua 100/33. If you have questions about weight loss or gain during Soliqua 100/33 treatment, talk with your doctor.

The cost you’ll pay for Soliqua 100/33 depends on whether you have insurance and other factors. For more information, see the “How much does Soliqua 100/33 cost?” section above.

Does Soliqua 100/33 cost less than Trulicity?

It’s possible. The cost of Soliqua 100/33 compared with Trulicity depends on several factors. These include whether you have insurance coverage, your dosage, and the pharmacy you use to fill your prescription.

To find out how the cost of Soliqua 100/33 and Trulicity compare, talk with your doctor or insurance provider (if you have one). They can tell you more about the costs of these medications.

Soliqua 100/33 is a biologic drug, which means it’s made from parts of living organisms. It doesn’t come in a biosimilar form. Biosimilars are like generic drugs. Unlike generics, which are made for nonbiologic drugs, biosimilars are made for biologic drugs.

Why is there such a cost difference between biologic drugs and biosimilar drugs?

Biologic drugs can be expensive because of the research and testing needed to ensure their safety and effectiveness. The manufacturer of a biologic drug can sell it exclusively for up to 12 years. When the biologic drug’s patent expires, other drugmakers can create biosimilar versions. This competition in the market may lead to lower costs for biosimilars. And because biosimilars are very similar to biologic drugs, they don’t need to be studied again. This can also lead to lower costs for biosimilars.

If you take Soliqua 100/33 long term, you may be able to lower your costs in the following ways:

Look into getting a 90-day supply of your medication. You may be able to get a 90-day supply of Soliqua 100/33 if approved by your insurance company. This could reduce your number of trips to the pharmacy and help lower the cost of Soliqua 100/33. If you’re interested in getting a 90-day supply of this drug, talk with your doctor, pharmacist, or insurance provider.

Use a mail-order pharmacy to get your medication. Using a mail-order pharmacy might help lower your cost for Soliqua 100/33. Plus, you could get your medication without leaving home. Some Medicare plans may help cover the cost of mail-order drugs. You may also be able to get a 90-day supply of the drug through mail order. If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need help covering the cost of Soliqua 100/33 or understanding your insurance, check out these resources:

On these sites, you can find insurance information, details on drug assistance programs, and links to savings cards and other services.

If you have questions about how to pay for your prescription, talk with your doctor or pharmacist.

If you still have questions about the cost of Soliqua 100/33, talk with your doctor or pharmacist. They may be able to give you a better idea of what you’ll pay for this drug. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you’d pay for Soliqua 100/33.

Examples of questions you may want to ask your doctor or insurance provider include:

  • How does the cost of Xultophy 100/3.6 compare with Soliqua 100/33?
  • Does the cost of Soliqua 100/33 depend on my dosage?
  • Are there lower-cost options to manage my condition if I can’t afford Soliqua 100/33?

To learn more about Soliqua, see these articles:

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.