Skyrizi (risankizumab-rzaa) is a prescription injection used to treat certain kinds of psoriasis or Crohn’s disease. This article gives details on Skyrizi and cost, prices with and without insurance, and resources that could lower the cost of Skyrizi.

Skyrizi is used in adults to treat:

For more details on Skyrizi, see this in-depth article.

The price you pay for Skyrizi can vary. It may depend on your treatment plan, your insurance coverage (if you have it), and the pharmacy you use. It will also depend on how much you have to pay for an office visit with your doctor to receive Skyrizi injections.

To find out how much you’ll pay for Skyrizi, talk with your doctor, pharmacist, or insurance provider.

Note: If you have insurance, you may need to get prior authorization before your insurance provider will cover Skyrizi. This means your insurer and your doctor will discuss the drug in regard to your treatment. Then your insurance company will determine whether the drug is covered. If Skyrizi requires prior authorization and you don’t receive it before you start treatment, you could pay the full cost of the drug.

Be sure to ask your insurance company whether Skyrizi requires prior authorization.

To save money on your Skyrizi prescription, explore these Optum Perks coupons. (Note: Optum Perks coupons cannot be used with any insurance copays or benefits.)

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Retail price refers to the manufacturer’s published list price and is up to date as of 3/2023. Retail and discounted prices are U.S.-only and can vary based on region and pharmacy. We cannot guarantee that the discounted price listed here will exactly match the price at your pharmacy. Please contact your pharmacy for the exact price.

Optum Perks and Healthline are subsidiaries of RVO Health.



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Below are answers to some frequently asked questions about Skyrizi and cost.

How much do Skyrizi injections cost per month without insurance and with insurance?

Prescription drugs usually cost less with insurance coverage than without it. If you have health insurance, call your insurance provider to see if Skyrizi is covered and exactly how much your monthly cost will be. The cost of the drug can vary with different plans. You may have a copay (a fixed amount you pay for certain drugs and services) depending on your type of coverage.

Similar to a manufacturer coupon, the drugmaker has a Skyrizi Complete Savings Card for eligible insured people. The card may reduce your prescription cost with each refill.

If you don’t have health insurance, you may qualify for the drugmaker’s assistance program called myAbbVie Assist. For more information, see the “Can I get help paying for Skyrizi?” section below.

The drugmaker also offers savings programs for people with and without insurance.

Does Medicare cover the cost of Skyrizi?

Whether Medicare covers the cost of Skyrizi depends on the type of prescription drug plan you have and possibly on how you receive your injections. (For more information about how Skyrizi injections are given, see this article.) Talk with your Medicare plan provider to learn if Skyrizi is covered and your exact cost of the drug.

Some Medicare plans may require a review process called prior authorization. Your doctor may need to show that the drug is medically necessary for you before your plan will cover it.

If you have Medicare and still need help paying for your Skyrizi prescription, you may be eligible for a government program called Extra Help.

For more information, talk with your doctor about cost-saving programs.

Skyrizi is a biologic drug, which means it’s made from parts of living organisms. It only comes as a brand-name drug and is not available in a biosimilar version. Biosimilars are like generic drugs in that they are equally effective versions of brand-name drugs. But unlike generics, which are made for nonbiologic drugs, biosimilars are made for biologics.

Why is there such a cost difference between biologic drugs and biosimilar drugs?

Biologic drugs can be expensive because of the research and testing needed to ensure their safety and effectiveness.

The drugmaker of a biologic can sell it for up to 12 years. When the biologic drug’s patent expires, other drugmakers can create biosimilar versions. This competition in the market may lead to lower costs for biosimilars. And because biosimilars are very similar to biologic drugs, they don’t need to be studied again. This can also lead to lower costs for biosimilars.

If you take Skyrizi long term, you may be able to lower your costs in the following ways:

Look into drugmaker discounts: You may be eligible for the Skyrizi Complete Savings Card. This could reduce your out-of-pocket treatment costs. To find out if you’re eligible, talk with your doctor, a pharmacist at a specialty pharmacy that supplies the drug, or a Skyrizi Nurse Ambassador at 866-759-7494.

Use a mail-order pharmacy to get your medication: Using a specialty mail-order pharmacy might help lower your cost for Skyrizi. And you could get your medication without leaving home. Some Medicare plans may help cover the cost of mail-order drugs. You may also be able to get a 90-day supply of the drug through mail order. If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest specialty online pharmacy options that could work for you.

If you need help covering the cost of Skyrizi or understanding your insurance, check out these websites:

On these sites, you can find insurance information, details on drug assistance programs, and links to savings cards and other services.

In addition, you can visit this page to access Optum Perks coupons and get price estimates for Skyrizi when you use the coupons. These coupons can provide significant savings on your prescription costs.

Note: Optum Perks coupons cannot be used with any insurance copays or benefits.

A program called myAbbVie Assist and the Skyrizi Complete Savings Card may also be available for Skyrizi.

If you still have questions about the cost of Skyrizi or how to pay for your prescriptions, talk with your doctor or pharmacist. They may be able to give you a better idea of what you’ll pay for this drug. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you’d pay for Skyrizi.

Examples of questions you may want to ask your doctor or insurance provider include:

  • Is Skyrizi available at all pharmacies or only at specialty pharmacies? And what is the cost difference between these types of pharmacies?
  • Will there be greater cost savings if I go to a doctor’s office for my injections compared with administering them myself?
  • Are there other lower cost drugs that could treat my condition?
  • Will there soon be a biosimilar available for Skyrizi?

To learn more about Skyrizi, see these articles:

To get information on different conditions and tips for improving your health, subscribe to any of Healthline’s newsletters. You may also want to check out the online communities at Bezzy. It’s a place where people with certain conditions can find support and connect with others.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.