If you have migraine, your doctor might suggest Reyvow as a treatment option.

Reyvow is a drug that’s prescribed to treat migraine episodes in adults as they happen. The drug isn’t taken to prevent migraine episodes.

The active ingredient in Reyvow is lasmiditan. An active ingredient is what makes a drug work.

This article describes the dosages of Reyvow, as well as its strengths and how to take the drug. To learn more about Reyvow, see this in-depth article.

Note: The chart below highlights the basics of Reyvow’s dosage. Be sure to read on for more details. And please keep in mind that this article covers Reyvow’s standard dosage schedule, which is provided by the drug’s manufacturer. But always follow the dosing instructions your doctor prescribes.

Reyvow formReyvow strengthsTypical dosageMaximum dosage
tablet50 milligrams (mg)

100 mg
50 mg, 100 mg, or 200 mg taken by mouth as needed to treat a migraine episodeno more than 1 dose in 24 hours

The information below describes typical dosages of Reyvow.

What is Reyvow’s form?

Reyvow comes as tablets that you swallow.

What strengths does Reyvow come in?

Reyvow comes in two different strengths:

  • 50 milligrams (mg)
  • 100 mg

What are the usual dosages of Reyvow?

The information below describes dosages that are commonly used or recommended. But be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Your doctor will likely start you on the lowest dosage of 50 mg and see how you do. Then they may adjust your dosage to reach the right amount to treat your migraine symptoms, such as severe headache.

Your dosage of Reyvow may be 50 mg, 100 mg, or 200 mg taken once per day. Do not take more than one dose of Reyvow in 24 hours, even if your migraine symptoms return. A second dose has not been shown to be effective. And taking more than one dose can increase your risk of rebound headaches (also referred to as medication overuse headaches).

Your doctor will ultimately prescribe the smallest dosage that eases your migraine symptoms.

Is Reyvow used long term?

Yes, Reyvow is typically used as a long-term treatment. If you and your doctor determine that Reyvow is safe and effective for you, you’ll likely take it long term to treat migraine episodes when they happen.

It’s not recommended that you take more than four doses of Reyvow in 30 days. It’s not known if this is safe.

Keep a migraine journal and talk with your doctor if you have more than four migraine episodes per month. They’ll discuss the best treatment options for your migraine episodes, including the safety of taking Reyvow.

Also, consider using a calendar to keep track of the days in a month that you’re taking Reyvow. This can help you avoid taking too much Reyvow, decreasing your risk of rebound headaches as a result.

Dosage adjustments

If you have certain health conditions, Reyvow may not be safe for you to take, or you may need a dosage adjustment. Examples of such conditions include serious liver disease, slow heart rate, and high blood pressure.

Tell your doctor about all health conditions you have and any other medications you’re taking. They’ll discuss if Reyvow is safe for you to take and whether you need a dose adjustment.

The dosage of Reyvow you’re prescribed may depend on several factors. These include:

  • other medications you may be taking
  • your age
  • other conditions you may have (see “Dosage adjustments” under “What is Reyvow’s dosage?”)

You’ll take Reyvow by mouth as needed to treat a migraine episode. The medication isn’t taken to prevent migraine symptoms.

Do not chew, break, or crush Reyvow tablets. You should swallow them whole, and you can take the medication with or without food.

Do not take more than one dose of Reyvow in a 24-hour period, even if your migraine symptoms return. Instead, contact your doctor. They can suggest other treatment options that you may take safely.

For information on Reyvow expiration, storage, and disposal, see this article.

Accessible drug containers and labels

If you find it hard to read the prescription label on your medication, tell your doctor or pharmacist. Some pharmacies may provide medication labels that:

  • have large print or use braille
  • feature a code that you can scan with a smartphone to change the text to audio

Your doctor or pharmacist may be able to recommend pharmacies that offer these accessibility features if your current pharmacy doesn’t.

If you have trouble opening blister packs, let your pharmacist know. They may be able to supply Reyvow in an easy-open container. Your pharmacist may also have some tips that can help make it simpler to open the drug’s container.

Yes, there is a risk of misuse with Reyvow. Misuse refers to taking a medication other than how it’s prescribed. This includes taking it more often or in higher doses than your doctor has prescribed. It can also mean taking a medication prescribed to someone else. These actions can be dangerous.

Reyvow can cause hallucinations (seeing or hearing things that aren’t there) or euphoria (feeling of intense excitement or joy). Some people may misuse Reyvow to experience these side effects of the drug.

Your doctor will discuss these risks of the drug. They’ll assess your risk of misusing Reyvow before you start taking it and during treatment.

Reyvow is a Schedule V controlled substance in the United States. This means the government strictly controls how the medication is prescribed and dispensed due to the risk of misuse.

Remember, overusing migraine medications like Reyvow can cause rebound headaches. It isn’t known if it’s safe to take more than four doses of Reyvow in 30 days.

Talk with your doctor about this risk and any concerns you have about taking the medication.

Do not take more Reyvow than your doctor prescribes. Taking more than this can lead to serious side effects.

What to do in case you take too much Reyvow

Call your doctor right away if you think you’ve taken too much Reyvow. You can also call 800-222-1222 to reach the American Association of Poison Control Centers, or use its online resource. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

The sections above describe the usual dosages provided by the drug’s manufacturer. If your doctor recommends Reyvow for you, they’ll prescribe the dosage that’s right for you.

Remember, you should not change your dosage of Reyvow without your doctor’s recommendation. Only take Reyvow exactly as prescribed. Talk with your doctor if you have questions or concerns about your current dosage.

Here are some examples of questions you may want to ask your doctor:

  • How long after taking my Reyvow dose will the medication take effect?
  • If a 50-mg dose doesn’t help with my migraine episode, should I take a higher dose next time?
  • Will I experience more side effects if I take a higher dose of Reyvow?

For personal stories and helpful information about migraine, sign up for Healthline’s migraine newsletter. And if you’re looking for a supportive community of others who live with migraine, consider joining Bezzy Migraine.


If Reyvow affects my ability to drive, would a lower dosage of the drug be better for me?



It’s not likely that a lower dosage would be better for you in this case.

Reyvow can cause dizziness or drowsiness regardless of the dosage. And a lower dosage of this drug may not be effective for your migraine symptoms.

You may not be aware of your loss of ability to drive safely when taking Reyvow. So it’s best to wait at least 8 hours after taking Reyvow to drive. The same goes for any activities that require you to be alert.

It’s important to talk with your doctor if you can’t wait 8 hours to drive or operate machinery after taking Reyvow. Your doctor will suggest other treatments to manage your migraine symptoms that are safer to take.

The Healthline Pharmacist TeamAnswers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.
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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.