Prochlorperazine is a generic prescription drug used to treat schizophrenia and severe nausea and vomiting. The drug’s cost may depend on factors such as your dosage, whether you have health insurance, and the pharmacy you use.

The price you pay for prochlorperazine can vary. It may depend on your treatment plan, the form of the drug you’re prescribed, your insurance coverage, and the pharmacy you use. It will also depend on how much you have to pay for an office visit with your doctor to receive prochlorperazine injections* if you receive that form of the drug.

To find out how much you’ll pay for prochlorperazine, talk with your doctor, pharmacist, or insurance provider. Or look below in the next section to learn how much you can save by using an Optum Perks coupon.

* This drug comes in several forms, including tablets and suppositories. It can also be given as an injection into a vein or an injection into a muscle by a healthcare professional.

To save money on your prochlorperazine prescription, explore these Optum Perks coupons.

Save on prochlorperazine with Optum Perks

Save up to 80% without using insurance.

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10mg Prochlorperazine Maleate (30 Tablets)


Save on prochlorperazine

Simply show the Optum Perks coupon at your preferred pharmacy and instantly save without using insurance. The coupon doesn't expire so be sure to save it for use with refills.

best price



Giant Eagle Pharmacy #0058


retail $27





retail $27



Target (CVS)


retail $27



CVS Pharmacy


retail $27

Retail price refers to the manufacturer’s published list price and is updated as of 3/2023. Retail and discounted prices are U.S.-only and can vary based on region and pharmacy. We cannot guarantee that the discounted price listed here will exactly match the price at your pharmacy. Please contact your pharmacy for the exact price.

Optum Perks and Healthline are subsidiaries of RVO Health.



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Prochlorperazine is a generic drug. A generic contains an exact copy of the active ingredient in a brand-name medication. (The active ingredient is what makes the drug work.) A generic is considered just as safe and effective as the original drug but tends to cost less.

Prochlorperazine suppository comes in a brand-name version called Compro. To find out how the costs of Compro and prochlorperazine suppositories compare, talk with your doctor, pharmacist, or insurance provider.

If you’ve been prescribed prochlorperazine suppository and you’re interested in Compro instead, talk with your doctor. They may recommend that you use one version instead of the other. In addition, you’ll need to check with your insurance provider as it may only cover one drug or the other.

Why is there such a cost difference between brand-name drugs and generics?

Years of research and testing are needed to ensure that brand-name drugs are safe and effective. This testing can make the drugs expensive. The manufacturer of a brand-name drug can sell the drug exclusively for up to 20 years. After that, other drugmakers can create generic versions. This competition in the market can lead to lower costs for generics. And because generics have the same active ingredients as brand-name drugs, they don’t need to be studied again. This can also lead to lower generic costs.

If you take prochlorperazine long term, you may be able to lower your costs in the following way:

Look into getting a 90-day supply of your medication. You may be able to get a 90-day supply of prochlorperazine if approved by your insurance company. This could reduce your number of trips to the pharmacy and help lower the cost of the drug. If you’re interested in getting a 90-day supply of prochlorperazine, talk with your doctor, pharmacist, or insurance provider.

If you need help covering the cost of prochlorperazine or understanding your insurance, check out these resources:

On these sites, you can find insurance information, details on drug assistance programs, and links to savings cards and other services.

If you have questions about how to pay for your prescription, talk with your doctor or pharmacist.

Below are answers to some frequently asked questions about prochlorperazine and cost.

How much does prochlorperazine cost without insurance?

Your cost for prochlorperazine will likely be higher without insurance, but what you pay will also depend on several factors. These include:

  • your dosage
  • the form of the drug your doctor prescribes for you
  • the cost of an appointment to receive prochlorperazine injections (if you receive this form of the drug)
  • whether you qualify and apply for any savings programs
  • the pharmacy you use
  • the days’ supply of medication you receive (such as a 30-day or 90-day supply)

To find out the exact cost of prochlorperazine without insurance, ask your doctor or pharmacist. You may also want to check with a few pharmacies to compare prices.

You can also visit Optum Perks* to get price estimates for prochlorperazine when you use coupons from the site. It’s important to note that Optum Perks coupons cannot be used with any insurance copays or benefits.

* Optum Perks is a sister site of Healthline.

Does Medicare cover prochlorperazine?

It’s possible. There are many different types of Medicare plans available, and your cost and coverage depend on your particular plan benefits. To find out whether your Medicare plan covers the cost of prochlorperazine, call your plan provider.

Your final cost may also depend on the price you need to pay to receive prochlorperazine injections* at a doctor’s office or clinic.

Keep in mind that your plan may have prior authorization requirements before it will cover prochlorperazine. (See the section just below for more information.)

You can also ask your doctor or pharmacist about the cost of prochlorperazine if you have Medicare.

* This drug comes in several forms, including tablets and suppositories. It can also be given as an injection into a vein or an injection into a muscle by a healthcare professional.

If you have insurance, you may need to get prior authorization before your insurance provider will cover prochlorperazine. This means your insurer and your doctor will discuss the drug in regard to your treatment. Then your insurance company will determine whether prochlorperazine is covered. If the drug requires prior authorization and you don’t receive it before you start treatment, you could pay the full cost for prochlorperazine.

Be sure to ask your insurance company whether this medication requires prior authorization.

If you still have questions about the cost of prochlorperazine, talk with your doctor or pharmacist. They may be able to give you a better idea of what you’ll pay for this drug. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you’d pay for prochlorperazine.

Examples of questions you may want to ask your doctor or insurance provider include:

  • What other lower cost, generic medications can I try for severe nausea?
  • What is the cost difference between prochlorperazine suppositories and tablets?
  • How does the cost of prochlorperazine tablets compare with other medications to treat schizophrenia?

To learn more about prochlorperazine, see this article.

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.