Prednisone is a generic prescription drug used to treat a wide range of inflammatory conditions, such as asthma. Prednisone’s cost may depend on factors such as your dosage, whether you have health insurance, and the pharmacy you use.

Keep reading for details on prednisone and cost, as well as how to save money on prescriptions. For more information on prednisone, including conditions it treats, see this in-depth article.

The price you pay for prednisone can vary. Your cost may depend on your treatment plan, your insurance coverage, and the pharmacy you use.

To find out how much you’ll pay for prednisone, talk with your doctor, pharmacist, or insurance provider. Or look below in the next section to learn how much you can save by using an Optum Perks coupon.

To save money on your prednisone prescription, explore these Optum Perks coupons.

Save on your prednisone prescription with Optum Perks

Save on prednisone without insurance.

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20mg prednisone (10 Tablets)

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Simply show the Optum Perks coupon at your preferred pharmacy and instantly save without using insurance. The coupon doesn't expire so be sure to save it for use with refills.

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Retail price refers to the manufacturer’s published list price and is up to date as of 3/2023. Retail and discounted prices are U.S.-only and can vary based on region and pharmacy. We cannot guarantee that the discounted price listed here will exactly match the price at your pharmacy. Please contact your pharmacy for the exact price.

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Below are answers to some frequently asked questions about prednisone and cost.

Does prednisone come as a shot or as eye drops? If so, what’s the cost?

No, prednisone doesn’t come as a shot (injection) or as eye drops. Prednisone is a drug that you swallow. It comes in three forms: an immediate-release tablet, a liquid solution, and a concentrated liquid solution.

Prednisone belongs to a group of drugs called corticosteroids (also known as steroids). Another steroid called cortisone can be given as an injection (but it doesn’t contain prednisone).

Prednisone also doesn’t come as an eye drop. But a drug with a similar name, prednisolone (Pred Forte), is available as an eye drop. Prednisolone is a steroid drug that’s similar to prednisone.

For cost information about prednisone, cortisone, or prednisolone, check with your doctor, pharmacist, or insurance plan.

What does prednisone cost without insurance?

The price you pay for prednisone without insurance can vary. Your cost may depend on factors such as the form of the drug you use, your dosage, and which pharmacy you use.

To find out how much you’ll pay for prednisone without insurance, talk with your doctor or pharmacist. Also, you may want to check with a few pharmacies to compare prices.

You can also visit Optum Perks* to get price estimates for prednisone when you use coupons from the site. It’s important to note that Optum Perks coupons cannot be used with any insurance copays or benefits.

* Optum Perks is a sister site of Healthline.

Does the cost of prednisone tablets depend on the strength (1 mg, 2.5 mg, 5 mg, 10 mg, 20 mg, 50 mg)?

Yes, the cost of prednisone tablets can vary with the strength prescribed. For example, 50-milligram (mg) prednisone tablets may be slightly more expensive than 10-mg prednisone tablets. But overall, prednisone is fairly inexpensive, and there isn’t much of a cost difference between strengths.

The cost of prednisone can also vary depending on the form you use. The cost of prednisone liquid solution or the concentrated liquid solution may be higher than the cost of prednisone tablets.

The prednisone immediate-release tablet,* the liquid solution, and the concentrated liquid solution only come as generic drugs. There’s also a prednisone delayed-release tablet,† but it comes only as a brand-name drug called Rayos. (This form isn’t available as a generic drug.)

A generic drug is an exact copy of the active drug in a brand-name medication. The generic is considered to be just as safe and effective as the original drug. Generics also tend to cost less than brand-name drugs.

To find out how the costs of Rayos and prednisone compare, talk with your doctor, pharmacist, or insurance provider.

If your doctor has prescribed prednisone and you’re interested in using Rayos instead, talk with your doctor. They may prefer one version over the other. In addition, you’ll need to check with your insurance provider. This is because it may only cover one drug or the other.

* An immediate-release drug is released into your body right away.
† A delayed-release drug is released into your body slowly over time.

Prednisone may be taken short term or long term, depending on your condition. If you take prednisone long term, you may be able to lower your costs in the following ways:

  • Look into getting a 90-day supply of your medication. You may be able to get a 90-day supply of prednisone if approved by your insurance company. This could reduce your number of trips to the pharmacy and help lower the cost of prednisone. If you’re interested in getting a 90-day supply of this drug, talk with your doctor or insurance provider.
  • Use a mail-order pharmacy to get your medication. Using a mail-order pharmacy might help lower your cost for prednisone. Plus, you could get your medication without leaving home. Some Medicare plans may help cover the cost of mail-order drugs. You may also be able to get a 90-day supply of the drug through mail order. If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need help covering the cost of prednisone or understanding your insurance, check out these websites:

On these sites, you can find insurance information, details on drug assistance programs, and links to savings cards and other services.

If you have questions about how you can pay for prednisone, you may also want to talk with your doctor or pharmacist.

If you still have questions about the cost of prednisone, talk with your doctor or pharmacist. They may be able to give you a better idea of what you’ll pay for this drug. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you’d pay for prednisone.

Examples of questions you may want to ask your doctor or insurance provider include:

  • Will my dosage of prednisone affect the cost?
  • How long will I need to take prednisone?
  • Are there any similar medications that could treat my condition for a lower cost?

Check out Healthline’s online newsletters for multiple sclerosis and allergies and asthma if you take prednisone for one of these conditions.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.