Methylprednisolone is a generic prescription drug used to treat many conditions by reducing inflammation or suppressing the immune system. The drug’s cost may depend on factors such as your dosage and whether you have health insurance.

The price you pay for methylprednisolone can vary. Your cost may depend on your treatment plan, your insurance coverage (if you have it), and the pharmacy you use. It will also depend on how much you have to pay for a hospital or office visit with your doctor to receive methylprednisolone.

To find out how much you’ll pay for this medication, talk with your doctor, pharmacist, or insurance provider. Or check out the section below to learn how much you can save by using an Optum Perks coupon.

To save money on your methylprednisolone prescription, explore these Optum Perks coupons. (Note: Optum Perks coupons cannot be used with any insurance copays or benefits.)

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Save on methylprednisolone without insurance.

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4mg methylprednisolone (21 Tablets)

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Simply show the Optum Perks coupon at your preferred pharmacy or order online and instantly save up to 80% without using insurance. The coupon doesn’t expire, so be sure to save it for refills.

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Retail price refers to the manufacturer’s published list price and is up to date as of 3/2023. Retail and discounted prices are U.S.-only and can vary based on region and pharmacy. We cannot guarantee that the discounted price listed here will exactly match the price at your pharmacy. Please contact your pharmacy for the exact price.

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Methylprednisolone is a generic drug. A generic contains an exact copy of the active drug in a brand-name medication. A generic is considered just as safe and effective as the original drug but tends to cost less.

Methylprednisolone comes in brand-name versions called Medrol, Depo-Medrol, and Solu-Medrol. To find out how the costs of these drugs and methylprednisolone compare, talk with your doctor, pharmacist, or insurance provider.

If you’ve been prescribed methylprednisolone and you’re interested in taking or receiving Medrol, Depo-Medrol, or Solu-Medrol instead, talk with your doctor. They may recommend using one version instead of the others. You’ll also need to check with your insurance provider, as it may not cover all versions of this drug.

Why is there such a cost difference between brand-name drugs and generics?

Years of research and testing are needed to ensure that brand-name drugs are safe and effective. This testing can make the drugs expensive. The manufacturer of a brand-name drug can sell the drug exclusively for up to 20 years. After that, other drugmakers can create generic versions. This competition in the market can lead to lower costs for generics. And because generics have the same active ingredients as brand-name drugs, they don’t need to be studied again. This can also lead to lower generic costs.

If you take methylprednisolone long term, you may be able to lower your costs in the following ways:

Look into getting a 90-day supply of your medication: You may be able to get a 90-day supply of methylprednisolone if approved by your insurance company. This could reduce your number of trips to the pharmacy and help lower the cost of the drug. If you’re interested in a 90-day supply of methylprednisolone, talk with your doctor, pharmacist, or insurance provider.

Use a mail-order pharmacy to get your medication: Using a mail-order pharmacy might help lower your cost for methylprednisolone. Plus, you could get your medication without leaving home. Some Medicare plans may help cover the cost of mail-order drugs. You may also be able to get a 90-day supply of methylprednisolone through mail order. If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need help covering the cost of methylprednisolone or understanding your insurance, check out these resources:

On these sites, you can find insurance information, details on drug assistance programs, and links to savings cards and other services.

If you have questions about how to pay for your prescription, talk with your doctor or pharmacist.

Below are answers to some frequently asked questions about methylprednisolone and cost.

How much does methylprednisolone cost without insurance?

The cost of methylprednisolone without insurance depends on several factors. But in general, your cost will be higher without insurance.

Your cost for this medication may depend on factors such as:

  • your treatment plan and dosage
  • whether you qualify and apply for any savings programs
  • the form of the drug you’re prescribed
  • the pharmacy you use
  • the supply of medication you receive (such as a 30-day or 90-day supply)
  • where you receive your dose of injectable methylprednisolone (if applicable), such as at a hospital, doctor’s office, or clinic

To find out the exact cost of methylprednisolone without insurance, ask your doctor or pharmacist. You may want to check with a few pharmacies to compare prices.

You can also visit Optum Perks* to get price estimates for methylprednisolone when you use coupons from the site. It’s important to note that Optum Perks coupons cannot be used with any insurance copays or benefits.

* Optum Perks is a sister site of Healthline.

Does Medicare cover methylprednisolone?

It’s possible. To find out whether your Medicare plan covers the cost of methylprednisolone, call your plan provider. There are many types of Medicare plans, and your cost and coverage depend on your particular plan’s benefits.

Your final cost may also depend on the price to receive methylprednisolone at a hospital, doctor’s office, or clinic.

Keep in mind that your plan may have prior authorization requirements before it will cover methylprednisolone. (See the “Prior authorization” section below for more information.)

You can also ask your doctor about the cost of methylprednisolone if you have Medicare.

If you have insurance, you may need to get prior authorization before your insurance provider will cover methylprednisolone.

This means your insurer and your doctor will discuss methylprednisolone in regard to your treatment. Then the insurance company will determine whether the drug is covered. If methylprednisolone requires prior authorization and you don’t receive it before you start treatment, you could pay the full cost of the drug.

Be sure to ask your insurance company whether methylprednisolone requires prior authorization.

If you still have questions about the cost of methylprednisolone, talk with your doctor or pharmacist. They may be able to give you a better idea of what you’ll pay for this drug. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual price you’d pay for methylprednisolone.

Examples of questions you may want to ask your doctor or insurance provider include:

  • Can I be prescribed the least expensive form of methylprednisolone?
  • How long will I need to plan to pay for my treatment with this medication?
  • What are my options if I can’t afford methylprednisolone?

To learn more about methylprednisolone, see these articles:

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.