Inbrija (levodopa inhalation powder) is a prescription drug that’s used to treat off-episodes of Parkinson’s disease. The drug comes as a powder that you’ll inhale into your lungs using an inhaler. Inbrija is typically used as needed.

Inbrija is used in adults to treat off-episodes of Parkinson’s disease (PD) who are also taking carbidopa/levodopa (Rytary, Sinemet).

The active ingredient in Inbrija is levodopa. (An active ingredient is what makes a drug work.) Inbrija belongs to a group of drugs called aromatic amino acids.

This article describes the dosage of Inbrija, as well as its strength and how to use it. To learn more about Inbrija, see this in-depth article.

This section describes the usual dosages of Inbrija. Keep reading to learn more.

What is Inbrija’s form?

Inbrija is available as a powder that comes in a capsule. The capsule is placed in an Inbrija inhaler to be breathed into your lungs as needed to manage off-episodes of PD.

What strength does Inbrija come in?

Inbrija comes in one strength of 42 milligrams (mg) per capsule.

What are the usual dosages of Inbrija?

The information below describes dosages that are commonly used or recommended. But be sure to take the dosage your doctor prescribes for you. They’ll determine the best dosage to fit your needs.

Dosage for Parkinson’s disease

The typical Inbrija dosage for adults to treat off-episodes of PD is two capsules (84 mg) inhaled using the Inbrija inhaler. The maximum daily dose of Inbrija is 420 mg (two capsules used five times per day).

You’ll only use Inbrija as needed to treat off-episodes. It’s not for regular use.

Talk with your doctor if you have questions about your dosage of Inbrija.

Is Inbrija used long term?

Yes, Inbrija is typically used as a long-term treatment. If you and your doctor determine that it’s safe and effective for your condition, you’ll likely use it long term.

Dosage adjustments

In certain cases, you may need dosage adjustments for Inbrija. Your doctor may adjust your dosage if you experience certain side effects from the medication, such as dyskinesia (involuntary movements).

If you have questions about any dosage adjustments you may need for Inbrija, talk with your doctor.

The dosage of Inbrija you’re prescribed may depend on any side effects you experience. These can include dyskinesia (involuntary movements) and impulse control disorders (such as a strong urge to spend money).

Your doctor will determine the best dosage for you. If you have questions about your dosage, talk with your doctor.

Inbrija is available as a capsule that’s used with an Inbrija inhaler. The typical dosage of Inbrija is two capsules (84 mg) inhaled as needed. This dosage can be used up to five times per day to manage off-episodes of PD.

Below are some tips on how to use Inbrija:

  • Don’t swallow Inbrija capsules. You should only use the capsules with the Inbrija inhaler.
  • Your doctor or pharmacist will show you how to take a dose of Inbrija. You’ll place one capsule into the Inbrija inhaler chamber and attach the mouthpiece. Then, you’ll place the mouthpiece into your mouth and inhale the medication. You’ll hold your breath for 5 seconds, then exhale.
  • For more detailed instructions, you can see the section of the prescribing information called instructions for use, or watch this helpful video from the manufacturer of Inbrija.
  • Do not suddenly stop taking Inbrija or rapidly reduce the dose you take. Doing these things can cause effects such as confusion and dangerously high fever. See the “Inbrija and withdrawal and dependence” section below for more information.

For information on the expiration, storage, and disposal of Inbrija, talk with your doctor or pharmacist.

Accessible drug containers and labels

Some pharmacies provide medication labels that:

  • have large print
  • use braille
  • feature a code you can scan with a smartphone to change the text to audio

Your doctor or pharmacist may be able to recommend pharmacies that offer these accessibility features if your current pharmacy doesn’t.

Do not use more Inbrija than your doctor prescribes, as this can lead to harmful effects.

Symptoms of overdose

Symptoms caused by an overdose can include:

What to do in case you use too much Inbrija

Call your doctor right away if you think you’ve used too much Inbrija. You can also call 800-222-1222 to reach America’s Poison Centers or use its online resource. But if you have severe symptoms, immediately call 911 (or your local emergency number) or go to the nearest emergency room.

Rapidly lowering doses or suddenly stopping the use of Inbrija can cause side effects similar to neuroleptic malignant syndrome. These side effects are confusion and a condition called withdrawal-emergent hyperpyrexia.

Symptoms include:

Do not suddenly stop using Inbrija on your own. If you need to stop the medication, your doctor will gradually lower your dose to stop treatment.

If you have questions about this side effect of Inbrija, talk with your doctor to learn more.

Below are answers to some commonly asked questions about Inbrija’s dosage.

Is Inbrija’s dosage similar to the dosage of Apokyn?

No. Although Inbrija (levodopa inhalation powder) and Apokyn (apomorphine hydrochloride) are both used to treat off-episodes of PD, however, there are differences. Their active ingredients, forms, and dosages all differ.

Inbrija comes as capsules that are used with an Inbrija inhaler to inhale the medication into your lungs. The dosage is two capsules (84 mg) used up to five times per day.

Apokyn comes as a liquid solution that’s injected under the skin. The starting dose is 0.2 milliliters (mL). If needed, the dose may be increased slowly to a maximum dosage of 0.6 mL per day.

Your doctor will prescribe the drug and the dosage that’s right for you.

To learn more about how these drugs compare, talk with your doctor.

How long does it take for Inbrija to start working?

Inbrija starts to work after your first dose. Typically, you’ll experience relief from your symptoms within 30 minutes of inhaling Inbrija. Your doctor will monitor you during treatment to check whether the drug is working to treat your condition.

If you have other questions about what to expect from your Inbrija treatment, talk with your doctor.

The sections above describe the usual dosage provided by Inbrija’s manufacturer. If your doctor recommends this drug, they’ll prescribe the dosage that’s right for you.

Remember, you should not change your dosage of Inbrija without your doctor’s recommendation. Only use Inbrija exactly as prescribed. Talk with your doctor if you have questions or concerns about your current dosage.

Here are some examples of questions you may want to ask your doctor:

  • Would I have a higher risk for side effects if I’m using Inbrija five times per day?
  • Will I need a dosage adjustment for Inbrija if I have liver problems?
  • Can I take my dose of Inbrija with other inhaled medications?

To learn more about Inbrija, see this article: Inbrija (levodopa).

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.