Humira (adalimumab) is a prescription drug that’s used for a variety of conditions. If you or your child has one of the conditions listed below, your doctor might suggest Humira as a treatment option.

Humira is used to treat:

This article describes the dosage of Humira, including its forms, strengths, and how to take the drug. To learn more about Humira, see this in-depth article.

Note: This article covers Humira’s typical dosages, which are provided by the drug’s manufacturer. But when using Humira, always take the dosage that your doctor prescribes.

Humira is a medication that’s injected under your skin. The drug comes in different forms and strengths.

You may receive your first dose of Humira in a doctor’s office or clinic. After that, you may give yourself Humira injections at home. You and your doctor will decide together whether using Humira at home is right for you.

What are the forms of Humira?

Humira comes as a liquid solution in three forms:

  • a single-dose, prefilled injection pen called Humira Pen
  • a single-dose, prefilled syringe
  • a single-dose vial (which is only used if receiving injections from your doctor)

What strengths does Humira come in?

Humira is available in several strengths, depending on the form of Humira you use.

The single-dose, prefilled injection pen comes in the following strengths:

  • 40 milligrams (mg) per 0.4 milliliters (mL) of solution
  • 40 mg per 0.8 mL of solution
  • 80 mg per 0.8 mL of solution

The single-dose, prefilled syringe comes in the following strengths:

  • 10 mg per 0.1 mL of solution
  • 10 mg per 0.2 mL of solution
  • 20 mg per 0.2 mL of solution
  • 20 mg per 0.4 mL of solution
  • 40 mg per 0.4 mL of solution
  • 40 mg per 0.8 mL of solution
  • 80 mg per 0.8 mL of solution

The single-dose vial comes in one strength: 40 mg per 0.8 mL.

What are the typical dosages of Humira?

When used for certain conditions, your first dose of Humira will be higher than your normal dose. This is called a “loading dose,” and it’s given to help the drug start working quickly to treat your condition.

Then, your doctor will lower your dosage over time to reach the right amount for you. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect.

The maximum dosage for Humira will depend on the condition it’s being used to treat.

The information below describes dosing schedules that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Dosage for ulcerative colitis

When Humira is used for ulcerative colitis in adults, treatment starts with a loading dose of 160 mg. This can be given as one dose in a single day or split into two doses over 2 days. For example, you might take 80 mg on day 1 and another 80 mg on day 2.

Two weeks after your loading dose (day 15), you’ll receive an 80-mg injection. And 2 weeks after that (day 29), you’ll start taking 40 mg every other week.

Humira is available in a starter kit that helps you follow this dosing schedule. The kit contains prefilled Humira pens.

Dosage for hidradenitis suppurativa

For treating hidradenitis suppurativa in adults, the first dose of Humira is a loading dose of 160 mg. You can take this as one dose in a single day. Or you can split it into two doses given over 2 days. For example, you might take 80 mg on day 1 and another 80 mg on day 2.

Two weeks after your loading dose (day 15), you’ll receive an 80-mg injection. And 2 weeks after that (day 29), you’ll start taking either 40 mg weekly or 80 mg every other week.

Humira is available in a starter kit that helps you follow this dosing schedule. The kit contains prefilled Humira pens.

Dosage for rheumatoid arthritis

When prescribed to treat rheumatoid arthritis (RA), the typical dosage of Humira is 40 mg every other week.

Your doctor might increase your Humira dosage for RA in certain situations. For example, if you aren’t taking methotrexate (Trexall) with Humira, your doctor may prescribe weekly dosing of 40 mg. Or instead of a weekly dose, they may prescribe 80 mg every other week.

Dosage for plaque psoriasis

For plaque psoriasis, you’ll start with a loading dose of 80 mg of Humira. One week after your loading dose, you’ll start taking 40 mg every other week.

Humira is available in a starter kit that helps you follow this dosing schedule. The kit contains prefilled Humira pens.

Dosage for psoriatic arthritis

When prescribed to treat psoriatic arthritis, the typical dosage of Humira is 40 mg every other week.

Dosage for Crohn’s disease

When used for Crohn’s disease in adults, Humira treatment begins with a loading dose of 160 mg. This can be given as one dose in a single day or split into two doses over 2 days. For example, you might take 80 mg on day 1 and another 80 mg on day 2.

Two weeks after your loading dose (day 15), you’ll receive a single dose of 80 mg. And 2 weeks after that (day 29), you’ll start taking 40 mg every other week.

Humira is available in a starter kit that helps you follow this dosing schedule. The kit contains prefilled Humira pens.

Dosage for uveitis

When Humira is used to treat uveitis in adults, the first dose is a loading dose of 80 mg. One week after your loading dose, you’ll start taking 40 mg every other week.

Humira is available in a starter kit that helps you follow this dosing schedule. The kit contains prefilled Humira pens.

Dosage for ankylosing spondylitis

When used to treat ankylosing spondylitis, the typical dosage of Humira is 40 mg every other week.

What’s the dosage of Humira for children?

The dosage of Humira for children depends on the condition the drug is used to treat. It also depends on the child’s body weight in kilograms (kg).* Below are the recommended Humira dosages for children.

* One kg is equal to about 2.2 pounds (lb).

Dosage for juvenile idiopathic arthritis

Humira is prescribed to treat juvenile idiopathic arthritis in children ages 2 years and older.

For this purpose, the typical Humira dosages are as follows:

  • In children who weigh 10 kg to 14 kg (about 22 lb to 31 lb): 10 mg every other week
  • In children who weigh 15 kg to 29 kg (about 33 to 64 lb): 20 mg every other week
  • In children who weigh 30 kg (about 66 lb) or more: 40 mg every other week

Children’s dosage for Crohn’s disease

Humira is used to treat Crohn’s disease in children ages 6 years and older.

The typical Humira dosages for this use are as follows:

  • In children who weigh 17 kg to 39 kg (about 37 lb to 86 lb):
    • On day 1: 80 mg
    • On day 15: 40 mg
    • Starting on day 29: 20 mg every other week
  • In children who weigh 40 kg (about 88 lb) or more:
    • On day 1: 160 mg as a single dose or split into two doses given on 2 consecutive days
    • On day 15: 80 mg
    • Starting on day 29: 40 mg every other week

Children’s dosage for hidradenitis suppurativa

Humira is prescribed to treat hidradenitis suppurativa in children ages 12 years and older.

For this purpose, the typical Humira dosages are as follows:

  • In children who weigh 30 kg to 59 kg (about 66 lb to 130 lb):
    • On day 1: 80 mg
    • Starting on day 8: 40 mg every other week
  • In children who weigh 60 kg (about 132 lb) or more:
    • On day 1: 160 mg as a single dose or split into two doses given on 2 consecutive days
    • On day 15: 80 mg
    • Starting on day 29: 40 mg every week or 80 mg every other week

Children’s dosage for uveitis

Humira is prescribed to treat specific types of uveitis in children ages 2 years and older. For this purpose, the typical Humira dosages are as follows:

  • In children who weigh 10 kg to 14 kg (about 22 lb to 31 lb): 10 mg every other week
  • In children who weigh 15 kg to 29 kg (about 33 lb to 64 lb): 20 mg every other week
  • In children who weigh 30 kg (about 66 lb) or more: 40 mg every other week

Children’s dosage for ulcerative colitis

Humira is used to treat ulcerative colitis in children ages 5 years and older. For this purpose, the typical Humira dosages are as follows:

  • In children who weigh 20 kg to 39 kg (about 44 lb to 86 lb):
    • On day 1: 80 mg
    • On day 8: 40 mg
    • On day 15: 40 mg
    • Starting on day 29: 20 mg every week or 40 mg every other week
  • In children who weigh 40 kg (about 88 lb) or more:
    • On day 1: 160 mg as a single dose or split into two doses given on 2 consecutive days
    • On day 8: 80 mg
    • On day 15: 80 mg
    • Starting on day 29: 40 mg every week or 80 mg every other week

Is Humira used long term?

Yes, Humira is typically used as a long-term treatment. If you and your doctor determine that Humira is safe and effective for you, it’s likely that you’ll use it long term.

You may receive your Humira injections in a doctor’s office or clinic. Or you may give yourself Humira injections at home.

Regardless of how the drug is given, it’s important that you don’t miss a dose of Humira. Getting consistent doses of the drug helps keep the levels of Humira in your body steady over time. This is important for treating your condition.

If you do miss an appointment to receive your Humira injection, call your doctor’s office as soon as possible to reschedule.

If you forget to give yourself an injection of Humira, inject your missed dose as soon as you remember. However, if it’s almost time for your next dose, just skip the missed dose. Then inject your next Humira dose at its regular time. You shouldn’t inject two doses of Humira at once to make up for a missed dose. Doing so could raise your risk for serious side effects.

If you are not sure whether you should inject Humira after you’ve missed a dose, call your doctor or pharmacist.

If you need help remembering to go to your Humira appointments or take your dose of Humira on time, try using a medication reminder. This can include setting an alarm, downloading a reminder app, or setting a timer on your phone. A kitchen timer can work, too.

The dosage of Humira you’re prescribed may depend on several factors. These include:

  • the type and severity of the condition you’re using Humira to treat
  • your age
  • the form of Humira you’re using
  • other medications you take
  • in children, their body weight

Humira is injected under your skin. You may receive your first dose of Humira in a doctor’s office or clinic. After that, you may be able to give yourself Humira injections at home.

Humira is injected into your thigh or abdomen (belly). Make sure to rotate where you inject the drug with each use. This will help lower your risk for pain, redness, or swelling after the drug is injected. You shouldn’t inject the drug into areas of your skin that are bruised, hard, red, or tender.

If you’re going to be using Humira at home, your doctor or pharmacist will show you how to give yourself Humira injections. You can also visit the drug manufacturer’s website or read the prescribing information for step-by-step instructions.

Don’t use more Humira than your doctor prescribes. Using more than this can lead to serious side effects.

What to do in case you use too much Humira

Call your doctor right away if you think you’ve taken/used too much Humira. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use their online resource. However, if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

The sections above describe the typical dosages provided by the drug manufacturer. If your doctor recommends Humira for you, they’ll prescribe the dosage that’s right for you.

Remember, you shouldn’t change your dosage of Humira unless your doctor recommends it. Only use Humira exactly as prescribed. Talk with your doctor if you have questions or concerns about your current dosage.

Here are some examples of questions you may want to ask your doctor:

  • Should my dosage change if Humira isn’t working well enough for me?
  • Does my dosage of Humira need to change if I’m taking other drugs along with it?
  • Will I be able to give myself injections of Humira at home?

You can subscribe to the Healthline newsletters for plaque psoriasis or rheumatoid arthritis if you use Humira for either of these conditions.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.