Evenity (romosozumab-aqqg) is a prescription drug used to treat osteoporosis. The drug comes as a liquid solution inside prefilled syringes for injection under the skin. It’s usually given once per month.
Evenity is used to treat postmenopausal osteoporosis in adult females.* Doctors prescribe it for people who have a high risk of bone fractures or when other medications can’t be used or haven’t worked well.
Evenity’s active ingredient is romosozumab-aqqg.† It’s a
This article describes the dosage of Evenity, as well as its strength and how it’s given. To learn more about Evenity, including its side effects, see this in-depth article.
* We use the term “female” in this article to refer to someone’s sex assigned at birth. For information about the difference between sex and gender, see this article.
† An active ingredient is what makes a drug work. The reason “-aqqg” appears at the end of its name is to show that the drug is distinct from similar medications that may be created in the future.
This section describes the usual dosages of Evenity. Keep reading to learn more.
What is Evenity’s form?
Evenity comes as a liquid solution inside prefilled syringes for injection under the skin.
What strength does Evenity come in?
Each syringe contains 105 milligrams (mg) per 1.17 milliliters (mL) of solution.
What’s the usual dosing schedule for Evenity?
The information below describes dosages that are commonly used or recommended. But your doctor will determine the best dosage to fit your needs.
Dosage for postmenopausal osteoporosis
The dosage of Evenity for postmenopausal osteoporosis is 210 mg once per month.
Each syringe contains 105 mg. A complete dose is two injections, one given after the other. These injections are given by your doctor or another healthcare professional in the clinic.
You’ll receive Evenity once per month for 12 months.
Your doctor will recommend that you also take calcium and vitamin D supplements while you’re receiving Evenity injections.
Is Evenity used long term?
Evenity is used for 12 months. You’ll receive your dose once per month for a total of 12 months.
Below are answers to some commonly asked questions about Evenity’s dosage.
How does the dosage of Evenity compare with the dosage of Prolia?
Both Evenity and Prolia (denosumab) are used to treat postmenopausal osteoporosis. But Prolia also has other approved uses, including treatment of osteoporosis in males.*
Evenity and Prolia are both injections given under the skin. Evenity is given as two injections once per month. Prolia is given as a single injection once every 6 months.
Evenity is prescribed for 12 months. Prolia may be given long term.
To learn more about how Evenity and Prolia compare, see this article.
* We use the term “male” in this article to refer to someone’s sex assigned at birth. For information about the difference between sex and gender, see this article.
Is there a situation where I can receive more than 12 doses of Evenity?
No, it’s unlikely that you would receive Evenity for more than 12 doses.
Evenity works mainly by increasing the growth of new bone. But this effect diminishes after 12 monthly doses.
If you and your doctor decide that you still need treatment for osteoporosis after you’ve completed treatment with Evenity, your doctor will suggest a different osteoporosis treatment. For example, they may suggest that you transition to treatment with either Prolia (denosumab) injections or Fosamax (alendronate) oral tablets.
Your doctor can provide more information about your treatment plan should you need continued treatment after 12 doses of Evenity.
Each month you’ll receive two injections given by your doctor or other healthcare professional. The injections are given under the skin of your thigh, abdomen, or upper arm.
If you miss your scheduled appointment, call your doctor’s office as soon as you remember to reschedule.
The sections above describe the usual dosage provided by the drug’s manufacturer. If your doctor recommends Evenity for you, they’ll prescribe the dosage that’s right for you.
Talk with your doctor if you have questions or concerns about your current dosage.
Here are some examples of questions you may want to ask your doctor:
- Do I need a dosage adjustment for Evenity if I have kidney problems?
- What happens if I miss a month or two of injections?
- Can I give myself Evenity injections at home?
- Can my dose of Evenity be put in a single syringe so I only receive one injection instead of two?
To learn more about Evenity, see these articles:
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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.