If you have eczema, your doctor might suggest Eucrisa as a treatment option for you. It’s a prescription medication used to treat mild to moderate eczema in adults and in some children.

Eucrisa is an ointment that works above and below your skin’s surface to reduce inflammation.

The active ingredient in Eucrisa is crisaborole, which belongs to a group of drugs called phosphodiesterase 4 (PDE4) inhibitors.

This article describes Eucrisa’s dosage, form, strength, and how to use it. To learn more about Eucrisa, see this in-depth article.

Note: This article covers Eucrisa’s typical dosages, which are provided by the drug’s manufacturer. But when using Eucrisa, always use the dosage your doctor prescribes.

Eucrisa is a topical prescription medication. (Topical means it’s applied to the skin.) Eucrisa’s recommended dosage instructions are described below.

What is Eucrisa’s form?

Eucrisa comes as an ointment in a tube. It’s not available in cream form.

What strength does Eucrisa come in?

Eucrisa only comes in 2% strength. This means there are 20 milligrams (mg) of the active ingredient crisaborole per gram (g) of ointment.

What is the typical dosage of Eucrisa?

The information below describes dosages that are commonly used or recommended. But be sure to use the dosage your doctor prescribes for you. They’ll determine the best dosage to fit your needs.

Apply a thin layer of Eucrisa ointment to the affected area of skin two times per day.

Eucrisa should only be applied externally to the skin. It should not be used in the:

  • eyes
  • mouth
  • vagina

What’s the dosage of Eucrisa for children?

The dosage of Eucrisa for children ages 3 months or older is the same as for adults.

Apply a thin layer of Eucrisa ointment to the affected area of skin twice daily.

Is Eucrisa used long term?

If you have constant eczema symptoms and respond well to Eucrisa, it may be used as a long-term treatment.

Some people have periods of remission in which eczema symptoms go away. But then flare-ups may occur in which symptoms return or get worse. Your doctor may advise you to stop using Eucrisa during a period of remission and start using it again during a flare-up.

Depending on your doctor’s instructions, you may use Eucrisa long term or only during flare-ups.

Eucrisa ointment is thinly applied twice per day on areas of the skin where there is eczema irritation.

Wash your hands after applying Eucrisa, unless your hands are being treated. If someone else applies Eucrisa for you, ask them to wash their hands after doing this.

For information on Eucrisa expiration, storage, and disposal, see this article.

Eucrisa is usually applied in the morning and again before bedtime. If you miss a dose, apply Eucrisa as soon as you remember. If it’s close to the time of your next dose, skip the one you missed. You’ll then apply the next dose at the regular time.

If you need help remembering when to apply your dose of Eucrisa, try using a medication reminder. This can include setting an alarm or downloading a reminder app on your phone.

Do not use more Eucrisa than your doctor prescribes. Using more than this can lead to side effects.

What to do in case you use too much Eucrisa

Call your doctor right away if you think you’ve used too much Eucrisa. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

The sections above describe the typical dosage provided by the drug’s manufacturer. If your doctor recommends Eucrisa for you, they’ll prescribe the dosage that’s right for you.

Remember, you shouldn’t change your dosage of Eucrisa without your doctor’s recommendation. Only use Eucrisa exactly as prescribed. Talk with your doctor if you have questions or concerns about your current dosage.

Here are some examples of questions you may want to ask your doctor:

  • Does the dosage of Eucrisa change with the severity of eczema?
  • Does a person’s age affect how they respond to Eucrisa?
  • Should my dosage change with an eczema flare-up?


How do I know I’m getting the right dose when I can’t exactly measure “a thin layer”?



You should apply just as much ointment as needed to cover your treatment areas. This will provide a thin layer over the places where you need medication on your skin.

Talk with your doctor if you have questions or need help identifying the areas you should be treating.

Dena Westphalen, PharmDAnswers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.
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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.