Cyltezo is a biosimilar prescription drug used to treat certain inflammatory conditions. Cyltezo’s cost may depend on factors such as your dosage, whether you have health insurance, and the pharmacy you use.

The price you pay for Cyltezo can vary. It may depend on your treatment plan and your insurance coverage.

To find out how much you’ll pay for Cyltezo, talk with your doctor, pharmacist, or insurance provider.

Below are answers to some frequently asked questions about Cyltezo and cost.

How does the cost of Cyltezo (Humira) compare with that similar drugs such as Hyrimoz, Hadlima, and Amjevita?

Like Cyltezo (adalimumab-adbm), the drugs Hyrimoz (adalimumab-adaz), Hadlima (adalimumab-bwwd), and Amjevita (adalimumab-atto) contain the active ingredient adalimumab. All four drugs are biosimilars of the brand-name drug Humira and are used to treat various inflammatory autoimmune conditions. These include rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.

The cost of Humira compared with the cost of these other drugs can depend on several factors. For example, different versions of this medication come in different forms of single-dose injection devices. These include single-dose prefilled glass syringes, single-dose prefilled pens, single-dose prefilled auto-injectors, and single-dose glass vials (for institutional use only). The devices each drug comes in may affect its cost.

Other factors that may affect how much you pay include:

  • whether there are any savings programs available for the drug you’re prescribed
  • whether you have insurance or are paying out of pocket
  • how long your treatment lasts

If you have questions about the cost of Cyltezo compared with the cost of similar medications, talk with your doctor, pharmacist, or insurance provider. They can share more details on treatment costs based on your specific situation.

Does Medicare cover Cyltezo?

It’s possible. To find out whether your Medicare plan covers the cost of Cyltezo, call your plan provider. There are many types of Medicare plans, and your cost and coverage depend on your particular plan’s benefits.

Keep in mind that your plan may have prior authorization requirements before it will cover Cyltezo. (See the “Prior authorization” section for more information.)

You can also ask your doctor about the cost of Cyltezo if you have Medicare.

Cyltezo is a biologic drug, which means it’s made from parts of living organisms. It’s a biosimilar version of the brand-name biologic drug Humira (adalimumab). Biosimilars are like generic drugs. But unlike generics, which are made for nonbiologic drugs, biosimilars are made for biologics.

If you’ve been prescribed Cyltezo and you’re interested in trying Humira instead, talk with your doctor. They may recommend that you try one version instead of the other. You’ll also need to check with your insurance provider, as it may only cover one drug or the other.

Why is there such a cost difference between biologic drugs and biosimilar drugs?

Biologic drugs can be expensive because of the research and testing needed to ensure their safety and effectiveness. The manufacturer of a biologic drug can sell it exclusively for up to 12 years. When the biologic drug’s patent expires, other drugmakers can create biosimilar versions. This competition in the market may lead to lower costs for biosimilars. And because biosimilars are very similar to biologic drugs, they don’t need to be studied again. This can also lead to lower costs for biosimilars.

If you receive Cyltezo long term, you may be able to lower your costs in the following ways:

Look into getting a 90-day supply of your medication: You may be able to get a 90-day supply of Cyltezo if approved by your insurance company. This could reduce your number of trips to the pharmacy and help lower the cost of Cyltezo. If you’re interested in a 90-day supply of this drug, talk with your doctor, pharmacist, or insurance provider.

Use a mail-order pharmacy to get your medication: Using a mail-order pharmacy might help lower your cost for Cyltezo. Plus, you could get your medication without leaving home. Some Medicare plans may help cover the cost of mail-order drugs. You may also be able to get a 90-day supply of the drug through mail order. If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need help covering the cost of Cyltezo or understanding your insurance, check out these resources:

On these sites, you can find insurance information, details on drug assistance programs, and links to savings cards and other services.

If you have questions about how to pay for your prescription, talk with your doctor or pharmacist.

If you have insurance, you may need to get prior authorization before your insurance provider will cover Cyltezo. This means your insurer and your doctor will discuss Cyltezo in regard to your treatment. Then, the insurance company will determine whether the drug is covered. If Cyltezo requires prior authorization and you don’t receive it before you start treatment, you could pay the full cost of the drug.

Be sure to ask your insurance company whether Cyltezo requires prior authorization.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.