Briviact (brivaracetam) is a prescription drug used to treat partial-onset seizures. Briviact comes as an oral tablet, an oral liquid solution, and as an injection given by a healthcare professional. It’s usually taken twice daily.

Briviact is used in adults and certain children to treat partial onset seizures (also called focal onset seizures).

The active ingredient in Briviact is brivaracetam. (An active ingredient is what makes a drug work.) Briviact belongs to a group of drugs called anticonvulsants.

This article describes the dosages of Briviact, as well as its strengths and how to take it. To learn more about Briviact, see this in-depth article.

This section describes the usual dosages of Briviact. Keep reading to learn more.

What are Briviact’s forms?

Briviact comes in three forms:

What strengths does Briviact come in?

Briviact comes in several strengths:

  • oral tablets:
    • 10 milligrams (mg)
    • 25 mg
    • 50 mg
    • 75 mg
    • 100 mg
  • oral liquid solution: 10 mg of drug per 1 milliliter (mL) of liquid in 300 mL bottles
  • liquid solution for injection: 50 mg of drug per 5 mL of liquid

What are the usual dosages of Briviact?

The dosage of Briviact you’re prescribed depends on your age, body weight, and other factors. Your doctor will likely start you on a recommended dosage. Then they’ll adjust it based on how well you tolerate the drug and how effectively it’s treating your condition.

The information below describes dosages that are commonly used or recommended. But be sure to take the dosage your doctor prescribes. They’ll determine the best dosage to fit your needs.

Dosage for seizure

The typical starting dosage of Briviact oral tablets or oral solution for adults with partial onset seizures is 50 mg twice per day. Based on how well you tolerate the dose, your doctor may increase or decrease it. The usual maintenance dosage range is 25–100 mg twice per day. The maximum dosage is 200 mg per day total.

Briviact injection is only used for a short time if you’re unable to take oral forms of the drug. A doctor or another health professional will give you doses as an IV infusion. You’ll receive these infusions in a hospital or clinic until you can start taking an oral form of the drug. Briviact infusions are given twice daily, and the dosage is the same as the oral forms of the drug.

If you have questions about your dosage, talk with your doctor or pharmacist.

What’s the dosage of Briviact for children?

Briviact is used to help treat partial onset seizures in children ages 1 month and older. The dosage used in children is based on their body weight for ages 1 month to less than 16 years. The dosage for children ages 16 years and older is the same as for adults.

For more information about Briviact’s dosage for children, talk with your child’s doctor or a pharmacist.

Is Briviact used long term?

Yes, Briviact is usually a long-term treatment. If you and your doctor determine that it’s safe and effective, you’ll likely take it long term.

Dosage adjustments

You may need dosage adjustments for Briviact in certain cases.

If you’re taking the medication rifampin while being treated with Briviact, your doctor will likely need to increase your normal dose of Briviact. This is because rifampin interacts with Briviact and can lower the drug’s effectiveness in your body.

If you have liver problems, your doctor may prescribe a lower dosage of Briviact for you. This drug is removed from your body through your liver. If you have liver problems, the drug could build up in your system, which could cause an increase in side effects.

Talk with your doctor if you have questions about dosage adjustments for Briviact.

The dosage of Briviact you’re prescribed may depend on several factors. These include:

  • the severity of your partial onset seizures
  • your age and body weight (for children)
  • other medications you take
  • other conditions you may have (see the “Dosage adjustments” section above)

Briviact is available as an oral tablet and oral liquid solution. You can take these forms with or without food. Do not crush, split, or chew Briviact tablets. If you have trouble swallowing tablets, see this article for tips on how to take this form of medication. You can also ask your doctor about the liquid oral solution if you have trouble swallowing pills.

You’ll take Briviact tablets with water twice per day around the same time every day as directed by your doctor.

If you or your child is prescribed Briviact liquid solution, use a measuring device to give the exact prescribed dose. Throw away any unused liquid solution after 5 months from the date the bottle was opened.

Briviact is also available as a liquid solution for IV infusion. You’ll receive these infusions from a healthcare professional at a hospital or clinic. You’ll only receive Briviact infusions for a short time until you can take an oral form of the drug.

For information on the expiration, storage, and disposal of Briviact, talk with your doctor or pharmacist.

Accessible drug containers and labels

Some pharmacies provide medication labels that:

  • have large print
  • use braille
  • feature a code you can scan with a smartphone to change the text to audio

Your doctor or pharmacist may be able to recommend pharmacies that offer these accessibility features if your current pharmacy doesn’t.

Let your pharmacist know if you have trouble opening medication bottles. They may have tips to help, or they may be able to supply Briviact in an easy-open container.

If you miss a dose of Briviact, take it as soon as you remember. But if it’s almost time for your next dose, skip the missed dose and take your next dose at its usual time. Do not take two doses of Briviact to make up for a missed dose. If you’re not sure whether you should take a missed dose, talk with your doctor or pharmacist.

If you need help remembering to take your dose of Briviact on time, try using a medication reminder. This can include setting an alarm or downloading a reminder app on your phone.

Briviact is a schedule V controlled substance that’s regulated by the United States federal government. It has a low risk of misuse, but misuse is possible. Misuse refers to taking a drug in a way other than how or why a doctor prescribes it. Examples of misuse include taking the drug more often or at higher doses than prescribed.

You should take Briviact only as your doctor has prescribed. Do not share your medication with anyone. Misuse increases the risk of overdose.

Do not take more Briviact than your doctor prescribes, as this can lead to harmful effects.

Symptoms of overdose

Symptoms caused by an overdose can include:

What to do in case you take too much Briviact

Call your doctor right away if you think you’ve taken too much Briviact. You can also call 800-222-1222 to reach America’s Poison Centers or use its online resource. But if you have severe symptoms, immediately call 911 (or your local emergency number) or go to the nearest emergency room.

Based on studies of the drug, there’s no evidence that taking Briviact can lead to physical dependence or withdrawal symptoms. (Dependence occurs when your body relies on a drug to function as usual. Withdrawal symptoms are side effects caused by suddenly stopping a drug.)

However, you should not suddenly stop taking Briviact, as this may increase your risk of seizure. If you need to stop Briviact treatment, your doctor will gradually lower your dosage over time, which can help reduce this risk.

Below are answers to some commonly asked questions about Briviact’s dosage.

Is Briviact’s dosage similar to that of levetiracetam?

No, the dosages for these drugs differ. Both Briviact and Keppra (levetiracetam) are approved to treat partial onset seizures. But levetiracetam is also approved to treat other types of seizure.

Levetiracetam comes as an oral tablet, extended-release* (ER) oral tablet, oral solution, and liquid solution for IV infusion by a healthcare professional.

The dose in milligrams for each drug differs. Levetiracetam may be taken once or twice per day depending on the form that’s prescribed. Briviact is taken twice per day.

Your doctor will prescribe the drug and the dosage that’s right for you. Talk with them to learn more about how these drugs compare.

* Extended-release dosage forms slowly release their contents into the body over time.

Does Briviact have a recommended loading dose?

No. Briviact does not have a recommended loading dose. (A loading dose is a higher dose of a drug that’s given when you start treatment. This can help certain medications start to work faster.)

Your doctor will start you on a dosage in Briviact’s recommended range. (For children, this is based on age and body weight). Your doctor will then adjust your dosage based on how you respond to the drug.

If you have other questions about a loading dose for Briviact, talk with your doctor or pharmacist.

Can I take 400 mg of Briviact per day?

No, there is no 400-mg per day dosage of Briviact. The recommended maximum dosage for people ages 16 years and older is 200 mg per day. The dosage of Briviact in children 1 month to less than 16 years is based on their body weight and is lower than the dosage in adults.

Your doctor will start you on the recommended dosage of Briviact and adjust it over time if needed. Always take the exact dosage they prescribe. Taking more than this can increase your risk of serious side effects from Briviact.

The sections above describe the usual dosages provided by Briviact’s manufacturer. If your doctor recommends this drug, they’ll prescribe the dosage that’s right for you.

Remember, you should not change your dosage of Briviact without your doctor’s recommendation. Only take this medication exactly as prescribed. Talk with your doctor if you have questions or concerns about your current dosage. Examples of questions you may want to ask include:

  • Can my dosage of Briviact be lowered if I experience side effects from my current dosage?
  • How does the dosage of Briviact compare with that of lamotrigine?
  • Will I need a Briviact dosage adjustment if I take other medications for partial onset seizure?

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.