Breztri Aerosphere (budesonide/glycopyrrolate/formoterol fumarate) is a prescription drug that’s used to manage COPD in adults. Breztri Aerosphere’s cost may depend on factors such as whether you have health insurance and the pharmacy you use.

Breztri retail price
Save up to $60 per fill off of the retail price
The retail price of Breztri is $645. Save up to $60 per fill off of the retail price.

The price you pay for Breztri Aerosphere can vary. Your cost may depend on your treatment plan, your insurance coverage (if you have it), and the pharmacy you use.

To find out how much you’ll pay for Breztri Aerosphere, talk with your doctor, pharmacist, or insurance provider. Or look below in the next section to learn how much you can save by using an Optum Perks coupon.

Note: If you have insurance, you may need to get prior authorization before your insurance provider will cover Breztri Aerosphere. This means your insurer and your doctor will discuss Breztri Aerosphere in regard to your treatment. Then your insurer will determine whether the drug is covered. If Breztri Aerosphere requires prior authorization and you don’t receive it before you start treatment, you could pay the full cost of the drug.

Be sure to ask your insurance company whether Breztri Aerosphere requires prior authorization.

To save money on your Breztri Aerosphere prescription, explore these Optum Perks coupons. (Note: Optum Perks coupons cannot be used with any insurance copays or benefits.)

Save on your Breztri Aerosphere prescription

Save on Breztri without insurance.

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10.7gm breztri (1 Inhaler)

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Simply show the Optum Perks coupon at your preferred pharmacy or order online and instantly save up to 80% without using insurance. The coupon doesn't expire, so be sure to save it for refills.

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Retail price refers to the manufacturer’s published list price and is up to date as of 3/2023. Retail and discounted prices are U.S.-only and can vary based on region and pharmacy. We cannot guarantee that the discounted price listed here will exactly match the price at your pharmacy. Please contact your pharmacy for the exact price.

Optum Perks and Healthline are subsidiaries of RVO Health.



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Below are answers to some frequently asked questions about Breztri Aerosphere and cost.

How much does Breztri Aerosphere cost with insurance and without insurance?

Your cost for Breztri Aerosphere may depend on several factors, including whether or not you are paying for Breztri Aerosphere with insurance. In general, you may pay more if you don’t have insurance.

If you have a private insurance plan with prescription drug coverage, your cost will depend on your specific plan’s benefits. Some plans have set costs for drugs, while others may require you to pay a percentage of Breztri Aerosphere’s cost. Keep in mind that some insurance plans may not cover Breztri Aerosphere.

To find out what Breztri Aerosphere may cost you, visit the Breztri Aerosphere savings and support site here. For additional savings options, see “Can I get help paying for Breztri Aerosphere?” below.

Whether you have insurance or not, you can visit Optum Perks* to get price estimates for Breztri Aerosphere when you use coupons from the site. It’s important to note that Optum Perks coupons cannot be used with any insurance copays or benefits.

If you have more questions about how much you’ll pay for Breztri Aerosphere, talk with your doctor or pharmacist.

Is the cost of Breztri Aerosphere covered by Medicare?

It’s possible. If you have Medicare, the amount you’ll pay for Breztri Aerosphere will depend on your specific Medicare plan. For example, Medicare Advantage plans and Medicare Part D plans have different copay options for the cost of brand-name drugs such as Breztri Aerosphere.

If you have questions about what you’ll pay for Breztri Aerosphere with Medicare, talk with your doctor, pharmacist, or Medicare plan provider.

How does the cost of Breztri Aerosphere compare with that of Trelegy Ellipta?

Both Breztri Aerosphere and Trelegy Ellipta are inhalation therapies used to treat chronic obstructive pulmonary disease (COPD). Both offer savings programs. You can learn more about the Breztri Zero Pay savings program here and Trelegy savings options here.

These drugs will likely cost about the same, and neither of them currently has a generic version available. Talk with your doctor, pharmacist, or insurance provider to find out what your COPD medication may cost you.

Breztri Aerosphere only comes as a brand-name drug. It’s not currently available in a generic version. A generic drug is an exact copy of the active drug in a brand-name medication. Generics tend to cost less than brand-name drugs.

Why is there such a cost difference between brand-name drugs and generics?

Years of research and testing are needed to ensure that brand-name drugs are safe and effective. This testing can make the drugs expensive. The manufacturer of a brand-name drug can sell the drug for up to 20 years. After that, other drugmakers can create generic versions. This competition in the market can lead to lower costs for generics. And because generics have the same active ingredients as brand-name drugs, they don’t need to be studied again. This can also lead to lower generic costs.

If you take Breztri Aerosphere long term, you may be able to lower your costs in the following ways:

  • Look into getting a 90-day supply of your medication: You may be able to get a 90-day supply of Breztri Aerosphere if approved by your insurance company. This could reduce your number of trips to the pharmacy and help lower the cost of Breztri Aerosphere. If you’re interested in getting a 90-day supply of this drug, talk with your doctor, pharmacist, or insurance provider.
  • Use a mail-order pharmacy to get your medication: Using a mail-order pharmacy might help lower your cost for Breztri Aerosphere. Plus, you could get your medication without leaving home. Some Medicare plans may help cover the cost of mail-order drugs. You may also be able to get a 90-day supply of the drug through mail order. If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need help covering the cost of Breztri Aerosphere or understanding your insurance, check out these resources:

On these sites, you can find insurance information, details on drug assistance programs, and links to savings cards and other services.

If you have questions about how to pay for your prescription, talk with your doctor or pharmacist.

If you still have questions about the cost of Breztri Aerosphere, talk with your doctor or pharmacist. They may be able to give you a better idea of what you’ll pay for this drug. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you’d pay for Breztri Aerosphere.

Examples of questions you may want to ask your doctor or insurance provider include:

  • Will my dosage of Breztri Aerosphere affect the cost?
  • Are there other lower-cost drugs that could treat my condition?
  • What are my options if I can’t afford my medication?

To learn more about Breztri Aerosphere, see these articles:

To get information on different conditions and tips for improving your health, subscribe to any of Healthline’s newsletters. You may also want to check out the online communities at Bezzy. It’s a place where people with certain conditions can find support and connect with others.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.