Beovu (brolucizumab-dbll) is prescribed to treat certain types of eye problems. The drug comes as a liquid solution for injection. After your starting doses, your eye specialist usually injects a dose every 8–12 weeks.
Beovu is used in adults to treat:
The active ingredient in Beovu is brolucizumab-dbll. (An active ingredient is what makes a drug work.) Beovu belongs to a group of drugs called vascular endothelial growth factor (VEGF) inhibitor.
This article describes the dosages of Beovu, as well as its strength and how it’s given. To learn more about Beovu, see this in-depth article.
This section describes the usual dosages of Beovu. Keep reading to learn more.
What is Beovu’s form?
Beovu is available as a liquid solution for injection. An eye specialist gives you the injections.
What strength does Beovu come in?
Beovu comes in one strength of 6 milligrams (mg) per 0.05 milliliters (mL).
What are the usual dosages of Beovu?
The starting dosage of Beovu depends on the condition it’s treating.
The information below describes dosages that are commonly used or recommended. Your eye specialist will determine the best dosage to fit your needs.
Dosage for wet AMD
You’ll begin Beovu treatment for wet AMD using a starting dosage. The typical starting dosage for adults is 6 mg every 25–31 days (about every 4 weeks) for the first three doses. After that, the ongoing (maintenance) dosage is 6 mg every 8–12 weeks.
If you have questions about your dosage of Beovu, talk with your eye specialist to learn more.
Dosage for diabetic macular edema
You’ll begin Beovu treatment for diabetic macular edema using a starting dosage. The typical starting dosage for adults is 6 mg every 39–45 days (about every 6 weeks) for the first five doses. Then the maintenance dosage for the rest of your treatment is 6 mg every 8–12 weeks.
If you have questions about your dosage of Beovu, talk with your eye specialist to learn more.
Is Beovu used long term?
Yes, this is likely. Your eye specialist will examine your eyes regularly to monitor how Beovu is working for your condition. Both of you can discuss whether Beovu is safe and effective for you. If you agree that it is, you’ll likely receive it long term.
The dosage of Beovu your eye specialist prescribes may depend on several factors. These include:
- the condition the drug is treating
- other medications you may be taking
Your eye specialist will give Beovu injections into your eye. You’ll receive them at your eye specialist’s office according to the dosing schedule for your condition. Your first several doses will be given about 4 or 6 weeks apart. Then your ongoing (maintenance) dosage will be 8–12 weeks apart.
It’s likely that you’ll have blurry vision temporarily after receiving an injection of Beovu. So you’ll need to arrange for someone to drive you home after your appointment.
Your eye specialist will examine your eyes regularly to monitor whether Beovu is working to treat your eye condition.
If you experience eye or vision problems during Beovu treatment, especially in the days following each dose, call your eye specialist right away. Symptoms to watch for include:
- eye pain
- eyeball redness
- sensitivity to light
- changes in vision
To learn more about possible side effects of Beovu, see this article.
If you miss an appointment to receive a dose of Beovu, call your eye specialist’s office as soon as possible to reschedule. They’ll schedule a time for you to receive the missed dose of Beovu. And if needed, they’ll adjust your dosing schedule accordingly.
If you need help remembering your appointments, try setting an alarm or downloading a reminder app on your phone.
Below are answers to some commonly asked questions about Beovu’s dosage.
Is Beovu’s dosage similar to the dosages of Eylea or Lucentis?
The forms and how often you receive each drug are similar, but there are some differences.
Beovu (brolucizumab-dbll), Eylea (aflibercept), and Lucentis (ranibizumab) all are biologic drugs (made from living cells). They belong to a group of medications called vascular endothelial growth factor (VEGF) inhibitors.
All three medications treat similar types of eye conditions, including wet AMD and diabetic macular edema. Eylea and Lucentis also are used to treat some other eye conditions. All three medications are eye injections given by an eye specialist.
The dose in milligrams and how often you receive each drug differ. Your eye specialist will prescribe the drug and the dosage that’s right for you.
To learn more about how these drugs compare, talk with your eye specialist.
How long does it take for Beovu to start working?
Beovu starts to work after your first dose. But the severity of your eye condition and your response to Beovu also affect how soon it starts working for you.
Your eye specialist will examine your eyes regularly to monitor how Beovu is working to treat your condition.
If you have other questions about what to expect from your Beovu treatment, talk with your eye specialist.
The sections above describe the usual dosages provided by Beovu’s drugmaker. If your eye specialist recommends this drug, they’ll prescribe the dosage that’s right for you.
Talk with your eye specialist if you have questions or concerns about your current dosage.
Here are some examples of questions you may want to ask your eye specialist:
- How does the dosage of Beovu compare with bevacizumab (Avastin)?
- If I have serious side effects when I begin treatment with Beovu, will you lower my dosage?
- Can I receive a higher dosage of Beovu if my condition isn’t improving?
To learn more about Beovu, see this “Beovu (brolucizumab)” article.
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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.