Ajovy (fremanezumab-vfrm) is a prescription drug used to help prevent migraine episodes in adults. It isn’t known to interact with alcohol, other drugs, or supplements. But if you have certain health factors, Ajovy may not be safe for you.

Ajovy comes as a liquid solution inside single-dose prefilled syringes and auto-injectors. You’ll inject Ajovy under your skin.

An interaction can occur because one substance causes another substance to have a different effect than expected. Interactions can also occur if you have certain health conditions.

Keep reading to learn about Ajovy’s possible interactions. And for more information about Ajovy, including details about its uses, see this article.

There are currently no reports of Ajovy interacting with other drugs. But this doesn’t mean that interactions with other drugs won’t be recognized in the future. For example, other drugs may be approved that could interact with Ajovy.

For this reason, it’s still important to talk with your doctor or pharmacist before taking any other drugs during Ajovy treatment.

Before you start Ajovy, tell your doctor and pharmacist about any prescription, over-the-counter, or other drugs you take. Sharing this information with them may help prevent possible interactions. (To learn whether Ajovy interacts with supplements, herbs, and vitamins, see the “Are there other interactions with Ajovy?” section below.)

If you have questions about drug interactions that may affect you, talk with your doctor or pharmacist.

Certain health conditions or other factors could raise your risk of harm if you inject Ajovy. In such cases, your doctor may not prescribe Ajovy for you. These are known as contraindications. Ajovy has one contraindication, which is described below.

Allergic reaction. If you’ve had an allergic reaction to Ajovy or any of its ingredients, your doctor likely won’t prescribe Ajovy. This is because injecting the drug could cause another allergic reaction. You can ask your doctor about other treatments that may be better options for you.

Ajovy is not known to interact with alcohol. But drinking alcohol can trigger migraine episodes in some people. And Ajovy is prescribed to help prevent migraine episodes.

During treatment with Ajovy, it’s important to avoid or limit factors that can trigger a migraine episode. So if you know that alcohol is a trigger for you, it may be best to avoid drinking it.

If you have questions about consuming alcohol during Ajovy treatment, talk with your doctor or pharmacist.

Ajovy may have other interactions. They could occur with supplements, foods, vaccines, or even lab tests. See below for details. Note that the information below does not include all other possible interactions with Ajovy.

Does Ajovy interact with supplements?

Before you start Ajovy, talk with your doctor and pharmacist about any supplements, herbs, and vitamins you take. Sharing this information with them may help you avoid possible interactions.

If you have questions about interactions that may affect you, talk with your doctor or pharmacist.

Ajovy and herbs

There are currently no reports of Ajovy interacting with herbs. But this doesn’t mean that interactions with herbs won’t be recognized in the future.

For this reason, it’s still important to check with your doctor or pharmacist before taking any of these products during treatment with Ajovy.

Ajovy and vitamins

There are currently no reports of Ajovy interacting with vitamins. But this doesn’t mean that vitamin interactions won’t be recognized in the future.

For this reason, it’s still important to check with your doctor or pharmacist before taking any of these products during treatment with Ajovy.

Does Ajovy interact with food?

There are currently no reports of Ajovy interacting with food. If you have questions about eating certain foods during your treatment with Ajovy, talk with your doctor.

Does Ajovy interact with vaccines or lab tests?

There are currently no reports of Ajovy interacting with vaccines or lab tests. But this doesn’t mean that such interactions won’t be recognized in the future.

For this reason, it’s still important to check with your doctor or pharmacist before receiving any vaccines or having lab tests done during Ajovy treatment.

Does Ajovy interact with cannabis or CBD?

There are currently no reports of Ajovy interacting with cannabis (commonly called marijuana) or cannabis products such as cannabidiol (CBD). But as with any drug or supplement, talk with your doctor before using cannabis with Ajovy.

Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.

Certain medical conditions or other health factors may raise the risk of interactions with Ajovy. Before starting Ajovy, talk with your doctor about your health history. They’ll determine whether Ajovy is right for you.

Health conditions or other factors that might interact with Ajovy include:

Pregnancy. It’s not known whether Ajovy is safe to inject during pregnancy. If you’re pregnant or planning a pregnancy, talk with your doctor before injecting Ajovy.

If you do inject Ajovy while pregnant, consider enrolling in the drug’s pregnancy registry. This registry collects details about pregnancy issues reported with Ajovy. To learn more, call 833-927-2605 or talk with your doctor.

Breastfeeding. It’s not known whether it’s safe to inject Ajovy while breastfeeding. If you’re breastfeeding or planning to do so, talk with your doctor about your options.

Allergic reaction. If you’ve had an allergic reaction to Ajovy or any of its ingredients, your doctor will likely not prescribe Ajovy. This is because injecting the drug could cause another allergic reaction. You can ask your doctor about other treatments that may be better choices for you.

Taking certain steps can help you avoid interactions with Ajovy. Before starting treatment, talk with your doctor and pharmacist. Things to discuss with them include:

  • Whether you drink alcohol or use cannabis.
  • Other medications you take, as well as any vitamins, supplements, and herbs. Your doctor or pharmacist can help you fill out a medication list.
  • What to do if you start taking a new drug during your Ajovy treatment.

It’s also important to understand Ajovy’s label and other paperwork that may come with the drug. Colored stickers that describe interactions may be on the label. And the paperwork (sometimes called the patient package insert or medication guide) may have other details about interactions. (If you did not get paperwork with Ajovy, ask your pharmacist to print a copy for you.) If you have difficulty reading or understanding this information, your doctor or pharmacist can help.

Injecting Ajovy exactly as prescribed can also help prevent interactions.

If you still have questions about Ajovy and its possible interactions, talk with your doctor.

Questions you may want to ask your doctor include:

  • Can I take other drugs to treat a migraine episode during Ajovy treatment?
  • Can I take other drugs to help prevent migraine episodes during Ajovy treatment?
  • What should I do if I become pregnant during Ajovy treatment?

To learn more about Ajovy, see these articles:

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.