Airsupra (albuterol/budesonide) is a prescription inhaler that’s used for asthma in adults. It also lowers the risk of an asthma attack. This brand-name drug isn’t available as a generic.

Airsupra basics

Airsupra contains the active ingredients albuterol and budesonide. (An active ingredient is what makes a drug work.)

Albuterol belongs to a group of drugs called short-acting beta-2 agonists. Budesonide belongs to a group of drugs called inhaled corticosteroids.

Airsupra is a brand-name medication that’s not available as a generic drug.

Note: Airsupra has been approved by the Food and Drug Administration (FDA), but it’s not available yet. The drug is expected to be available in 2024. For more information, talk with your doctor or pharmacist.

Like most drugs, Airsupra may cause mild or serious side effects. The lists below describe some of the more common side effects that Airsupra may cause. These lists don’t include all possible side effects.

Keep in mind that side effects of a drug can depend on:

  • your age
  • other health conditions you have
  • other medications you take

Your doctor or pharmacist can tell you more about the potential side effects of Airsupra. They can also suggest ways to help reduce side effects.

Mild side effects

Here’s a list of some of the mild side effects that Airsupra can cause. To learn about other mild side effects, talk with your doctor or pharmacist, or read Airsupra’s prescribing information.

Mild side effects of Airsupra that have been reported include:

Mild side effects of many drugs may go away within a few days to a couple of weeks. But if they become bothersome, talk with your doctor or pharmacist.

* To learn more about this side effect, see the “Allergic reaction” section below.

Serious side effects

Serious side effects from Airsupra can occur, but they aren’t common. If you have serious side effects from Airsupra, call your doctor right away. But if you think you’re having a medical emergency, you should call 911 or your local emergency number.

Serious side effects of Airsupra that have been reported include:

* To learn more about this side effect, see the “Allergic reaction” section below.

Allergic reaction

Some people may have an allergic reaction to Airsupra. While allergic reaction wasn’t reported in studies of Airsupra, it has been reported since the drug was approved for use.

Symptoms of a mild allergic reaction can include:

A more severe allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include swelling under your skin, usually in your eyelids, lips, hands, or feet. They can also include swelling of your tongue, mouth, or throat, which can cause trouble breathing.

Call your doctor right away if you have an allergic reaction to Airsupra. But if you think you’re having a medical emergency, call 911 or your local emergency number.

Your doctor will recommend the dosage of Airsupra that’s right for you. Below are commonly used dosages, but always take the dosage your doctor prescribes.

Form and strength

Airsupra comes as a metered-dose inhaler in one strength: 90 micrograms (mcg) albuterol/80 mcg budesonide per inhalation.

Recommended dosage

For the short-term treatment or prevention of asthma symptoms, you’ll take two inhalations (puffs) of Airsupra as needed.

You should not use more than 12 puffs (six doses) of Airsupra during a 24-hour period. If you feel the need to use Airsupra this frequently, talk with your doctor. Your asthma symptoms may require a different treatment.

How to use

Your doctor will explain how to use Airsupra. They’ll also explain how much to take and how often. Be sure to follow your doctor’s instructions.

Airsupra comes as a metered-dose inhaler. To use it, you’ll press down on the canister at the same time that you breathe in through the mouthpiece. You can view step-by-step instructions in Airsupra’s prescribing information. Your doctor or pharmacist will also show you how to use Airsupra when you’re first prescribed the drug.

Questions about using Airsupra

Below are some common questions about using Airsupra.

  • Should I take Airsupra with food? Food doesn’t affect how Airsupra works. You can use a dose of Airsupra regardless of when you last ate. But you should not use the drug when you have food or liquid in your mouth.
  • Will I need to use Airsupra long term? Yes, you’ll likely use Airsupra long term if you and your doctor agree the drug is working well for you.


Do not take more Airsupra than your doctor prescribes. Using more than this can lead to negative effects.

Symptoms of overdose

Symptoms caused by an overdose can include:

What to do in case you take too much Airsupra

Call your doctor if you think you’ve taken too much Airsupra. You can also call 800-222-1222 to reach America’s Poison Centers or use its online resource. But if you have severe symptoms, immediately call 911 or your local emergency number. Or go to the nearest emergency room.

Whether you have health insurance or not, cost may be a factor when you’re considering Airsupra. What you’ll pay for Airsupra may depend on several things, including your treatment plan.

You can check out this article to learn more about saving money on prescriptions.

Airsupra is used to treat and help prevent bronchospasm (tightening of the muscles that line your airways) and other symptoms in people with asthma. It’s also used to lower the risk of an asthma attack.

Asthma is a condition caused by inflammation that affects the lining of the airways. Inflammation causes swelling and bronchospasms. It also increases the amount of mucus in the airways. This makes it hard to breathe and causes other asthma symptoms such as wheezing and coughing.

Airsupra works to treat asthma by reducing inflammation in the airways and relaxing the muscles lining them.

Below is important information you should consider before using Airsupra.


Taking a drug with certain medications, vaccines, foods, and other things can affect how the drug works. These effects are called interactions.

Airsupra can interact with several other medications. It can also interact with certain supplements as well as certain foods.

Before taking Airsupra, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

Drug interactions

Below is a list of medications that can interact with Airsupra. This list does not contain all drugs that may interact with Airsupra. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Drug group or drug nameDrug examples
certain antibiotics• clarithromycin
• ciprofloxacin (Cipro)
certain antifungalsketoconazole
• itraconazole (Sporanox, Tolsura)
certain antiretrovirals• ritonavir (Norvir)
• nelfinavir (Viracept)
cyclosporine (Neoral, Sandimmune, Gengraf)
certain drugs for heart conditions• diltiazem (Cardizem CD, others)
verapamil (Verelan, others)
beta-blockers• atenolol (Tenormin)
• propranolol (Inderal LA and Inderal XL)
diuretics (water pills)• furosemide (Lasix)
• bumetanide (Bumex)
digoxin (Lanoxin)
monoamine oxidase inhibitors• phenelzine (Nardil)
• isocarboxazid (Marplan)

Airsupra and alcohol

Alcohol is not known to interact with Airsupra. It’s likely safe to consume alcohol during your Airsupra treatment.

Pregnancy and breastfeeding

It’s not known whether it’s safe to use Airsupra during pregnancy or while breastfeeding. If you’re pregnant or breastfeeding, or planning to become pregnant or to breastfeed, talk with your doctor before starting Airsupra treatment.

If you and your doctor decide you’ll use Airsupra while pregnant, consider joining the pregnancy registry for asthma drugs. Pregnancy registries help doctors and patients make safe treatment decisions during pregnancy. You can learn more or join the registry online or by calling 1-877-311-8972.


Airsupra can sometimes cause harmful effects in people who have certain conditions. This is known as a drug-condition interaction. Other factors may also affect whether Airsupra is a good treatment option for you.

Talk with your doctor about your health history before you take Airsupra. Be sure to tell them if any of the following factors apply to you:

Find answers to some commonly asked questions about Airsupra.

Does Airsupra cause long-term side effects?

It’s possible. Examples of long-term side effects reported in Airsupra’s studies include:

Talk with your doctor to learn more about possible side effects of Airsupra and how long they may last.

Will Airsupra cure my asthma?

No, Airsupra does not cure asthma. There’s currently no cure for this condition. However, Airsupra works to manage the symptoms of asthma. It can also help prevent an asthma attack.

If you have other questions about what to expect from your Airsupra treatment, talk with your doctor.

Is Airsupra used for cough?

Airsupra is not approved to treat cough. But your doctor may prescribe it off-label for this use. (With off-label use, doctors prescribe a drug for a purpose other than what it’s approved for.)

Airsupra is approved to treat symptoms of asthma, which sometimes includes cough. But it’s not approved for use to treat cough that isn’t related to asthma.

To learn more about treatment options for cough, including Airsupra, talk with your doctor.

Other drugs are available that can treat your condition. If you’d like to explore an alternative to Airsupra, talk with your doctor. They can tell you about other medications that might work well for you.

The following drugs are similar to Airsupra:

  • other short-acting beta-2 agonists, such as:
    • albuterol
  • inhaled corticosteroids, such as:
    • beclomethasone (Qvar RediHaler)
  • combination inhalers, such as:
    • fluticasone propionate/salmeterol (Advair)
    • mometasone/formoterol (Dulera)

If you have questions about taking Airsupra, talk with your doctor or pharmacist. Questions you may want to ask include:

  • Will I take Airsupra alone or with other medications to treat my asthma?
  • How does Airsupra fit into my asthma action plan?
  • If I can’t afford Airsupra, what other treatment options are available?
  • Can you recommend ways to lower my risk of infection while I’m taking Airsupra?
  • Should I take a calcium and vitamin D supplement to help prevent weak bones while I’m taking Airsupra?

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.